Ketogenic diet and cancer treatment
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/31806 |
Resumo: | Faced with an expressive increase in the last decades in the case of cancer in the world population, the need for a dietary strategy supporting conventional treatment for patients diagnosed with cancer has become evident, with the aim of obtaining positive results in the fight against the disease. This literature review study aimed to present the ketogenic diet (KD) as a nutritional intervention and its proposed mechanisms against cancer cells, as well as to characterize limitations in the literature currently available. The studies were selected from the BIREME, PUBMED, ScienceDirect databases, as well as books, institutional and government websites; using descriptors such as: ketogenic diet; chronic diseases; cancer; cancer treatment and oxidative stress; they were used in the English language. It has been proposed that, in the absence of blood glucose, cancer cells decrease their proliferation and enter a state of oxidative stress, as a consequence of a high-fat, carbohydrate-deficient diet, thus making them more sensitive to standardized treatments. such as radiation and chemotherapy. However, there is a need for further studies in humans in order to obtain better results and conclusions regarding this nutritional intervention. |
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Ketogenic diet and cancer treatmentDieta cetogénica y tratamiento del câncerDieta cetogênica e o tratamento do câncerDietaDieta cetogênicaCâncerDoenças crônicas. DietaDieta cetogénicaCáncerEnfermedades crónicas.DietKetogenic dietCancerChronic diseases.Faced with an expressive increase in the last decades in the case of cancer in the world population, the need for a dietary strategy supporting conventional treatment for patients diagnosed with cancer has become evident, with the aim of obtaining positive results in the fight against the disease. This literature review study aimed to present the ketogenic diet (KD) as a nutritional intervention and its proposed mechanisms against cancer cells, as well as to characterize limitations in the literature currently available. The studies were selected from the BIREME, PUBMED, ScienceDirect databases, as well as books, institutional and government websites; using descriptors such as: ketogenic diet; chronic diseases; cancer; cancer treatment and oxidative stress; they were used in the English language. It has been proposed that, in the absence of blood glucose, cancer cells decrease their proliferation and enter a state of oxidative stress, as a consequence of a high-fat, carbohydrate-deficient diet, thus making them more sensitive to standardized treatments. such as radiation and chemotherapy. However, there is a need for further studies in humans in order to obtain better results and conclusions regarding this nutritional intervention.Ante un aumento expresivo en las últimas décadas de casos de cáncer en la población mundial, se ha hecho evidente la necesidad de una estrategia dietética que apoye el tratamiento convencional de los pacientes diagnosticados de cáncer, con el objetivo de obtener resultados positivos en la lucha contra la enfermedad. Este estudio de revisión de la literatura tuvo como objetivo presentar la dieta cetogénica (DC) como una intervención nutricional y sus mecanismos propuestos contra las células cancerosas, así como caracterizar las limitaciones en la literatura actualmente disponible. Los estudios fueron seleccionados de las bases de datos BIREME, PUBMED, ScienceDirect, así como de libros, sitios web institucionales y gubernamentales; utilizando descriptores como: dieta cetogénica; Enfermedades crónicas; cáncer; tratamiento del cáncer y estrés oxidativo; se usaron en el idioma inglés. Se ha propuesto que, en ausencia de glucosa en sangre, las células cancerosas disminuyen su proliferación y entran en un estado de estrés oxidativo, como consecuencia de una dieta rica en grasas y deficiente en hidratos de carbono, haciéndolas así más sensibles a los tratamientos estandarizados. como la radiación y la quimioterapia. Sin embargo, es necesario realizar más estudios en humanos para obtener mejores resultados y conclusiones con respecto a esta intervención nutricional.Diante de um aumento expressivo nas últimas décadas no caso de câncer na população mundial, evidenciou-se a necessidade de uma estratégia dietética coadjuvante ao tratamento convencional para pacientes diagnosticados com câncer, tendo como intuito obter resultados positivos na luta contra a doença. Este estudo de revisão literária teve como objetivo apresentar a dieta cetogênica (KD) como intervenção nutricional e seus mecanismos propostos contra as células oncológicas, como também caracterizar delimitações na literatura presentemente disponível. Os estudos foram selecionados pelas bases de dados BIREME, PUBMED, ScienceDirect e além de livros, sites institucionais e governamentais; utilizando-se descritores como: dieta cetogênica; doenças crônicas; câncer; tratamento do câncer e estresse oxidativo; os mesmos foram utilizados na língua inglesa. Foi proposto que, as células cancerígenas na ausência de glicose sanguínea diminuem sua proliferação e entram em um estado de estresse oxidativo, por consequência de uma dieta com alto teor em gordura e com déficit de carboidrato, assim deixando-as mais sensíveis aos tratamentos padronizados, como por exemplo, radiação e quimioterapia. Todavia, há a necessidade de maiores estudos em humanos para que se possa ter melhores resultados e conclusões a respeito dessa intervenção nutricional.Research, Society and Development2022-07-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3180610.33448/rsd-v11i9.31806Research, Society and Development; Vol. 11 No. 9; e28211931806Research, Society and Development; Vol. 11 Núm. 9; e28211931806Research, Society and Development; v. 11 n. 9; e282119318062525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/31806/27134Copyright (c) 2022 Daniel Donato de Sousa; João Gabriel Toledo Pacheco Silva; Dayanne da Costa Maynardhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSousa, Daniel Donato de Silva, João Gabriel Toledo Pacheco Maynard, Dayanne da Costa2022-07-21T12:36:16Zoai:ojs.pkp.sfu.ca:article/31806Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:48:01.504283Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Ketogenic diet and cancer treatment Dieta cetogénica y tratamiento del câncer Dieta cetogênica e o tratamento do câncer |
title |
Ketogenic diet and cancer treatment |
spellingShingle |
Ketogenic diet and cancer treatment Sousa, Daniel Donato de Dieta Dieta cetogênica Câncer Doenças crônicas. Dieta Dieta cetogénica Cáncer Enfermedades crónicas. Diet Ketogenic diet Cancer Chronic diseases. |
title_short |
Ketogenic diet and cancer treatment |
title_full |
Ketogenic diet and cancer treatment |
title_fullStr |
Ketogenic diet and cancer treatment |
title_full_unstemmed |
Ketogenic diet and cancer treatment |
title_sort |
Ketogenic diet and cancer treatment |
author |
Sousa, Daniel Donato de |
author_facet |
Sousa, Daniel Donato de Silva, João Gabriel Toledo Pacheco Maynard, Dayanne da Costa |
author_role |
author |
author2 |
Silva, João Gabriel Toledo Pacheco Maynard, Dayanne da Costa |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Sousa, Daniel Donato de Silva, João Gabriel Toledo Pacheco Maynard, Dayanne da Costa |
dc.subject.por.fl_str_mv |
Dieta Dieta cetogênica Câncer Doenças crônicas. Dieta Dieta cetogénica Cáncer Enfermedades crónicas. Diet Ketogenic diet Cancer Chronic diseases. |
topic |
Dieta Dieta cetogênica Câncer Doenças crônicas. Dieta Dieta cetogénica Cáncer Enfermedades crónicas. Diet Ketogenic diet Cancer Chronic diseases. |
description |
Faced with an expressive increase in the last decades in the case of cancer in the world population, the need for a dietary strategy supporting conventional treatment for patients diagnosed with cancer has become evident, with the aim of obtaining positive results in the fight against the disease. This literature review study aimed to present the ketogenic diet (KD) as a nutritional intervention and its proposed mechanisms against cancer cells, as well as to characterize limitations in the literature currently available. The studies were selected from the BIREME, PUBMED, ScienceDirect databases, as well as books, institutional and government websites; using descriptors such as: ketogenic diet; chronic diseases; cancer; cancer treatment and oxidative stress; they were used in the English language. It has been proposed that, in the absence of blood glucose, cancer cells decrease their proliferation and enter a state of oxidative stress, as a consequence of a high-fat, carbohydrate-deficient diet, thus making them more sensitive to standardized treatments. such as radiation and chemotherapy. However, there is a need for further studies in humans in order to obtain better results and conclusions regarding this nutritional intervention. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-07-10 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/31806 10.33448/rsd-v11i9.31806 |
url |
https://rsdjournal.org/index.php/rsd/article/view/31806 |
identifier_str_mv |
10.33448/rsd-v11i9.31806 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/31806/27134 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 9; e28211931806 Research, Society and Development; Vol. 11 Núm. 9; e28211931806 Research, Society and Development; v. 11 n. 9; e28211931806 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052717052461056 |