HIV elite controller: case report
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/33057 |
Resumo: | The objective of the study is to report the case of a female patient with double sorological confirmation in rapid tests for anti-HIV antibodies for more 10 years, being follow up by the Service Specialized Attendance/Testing and Counseling Center, who never showed signs of clinical disease progression and maintain an undetectable viral load even in the absence of any antirretroviral therapy. A case of great relevance for the scientific community, given the rarity of the clinical evolution presented and the morbidity and mortality of this type of infection in Brazil, since according to data from the Ministry of Health the number of infected is close to 1 million. The possibility of natural control of human immunodediciency virus (HIV) infection without antiretroviral therapy, such as the one reported in the case, opens perspectives for understanding the specific immunological and biomolecular mechanisms involved in protection and for the possibility of a spontaneous functional cure of the infection. |
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HIV elite controller: case reportControlador de elite del VIH: informe de un caso HIV controlador de elite: relato de casoHIVAnticorpos anti-HIVPortador sadioSíndrome de imunodeficiência adquiridaRelatos de casos.VIHAnticuerpos anti-VIHPortador sanoSíndrome de inmunodeficiencia adquiridaReporte del caso.HIVHIV antibodiesCarrier stateAcquired immunodeficiency syndromeCase reports.The objective of the study is to report the case of a female patient with double sorological confirmation in rapid tests for anti-HIV antibodies for more 10 years, being follow up by the Service Specialized Attendance/Testing and Counseling Center, who never showed signs of clinical disease progression and maintain an undetectable viral load even in the absence of any antirretroviral therapy. A case of great relevance for the scientific community, given the rarity of the clinical evolution presented and the morbidity and mortality of this type of infection in Brazil, since according to data from the Ministry of Health the number of infected is close to 1 million. The possibility of natural control of human immunodediciency virus (HIV) infection without antiretroviral therapy, such as the one reported in the case, opens perspectives for understanding the specific immunological and biomolecular mechanisms involved in protection and for the possibility of a spontaneous functional cure of the infection.El objetivo del estudio es reporte del caso de un paciente femenino, con doble confirmación serológica en pruebas rápidas para detección de anticuerpos anti-VIH desde hace más de 10 años, siendo seguida por el Servicio de Atención Especializada/Centro de Pruebas y Consejería, que nunca mostró signos de progresión clínica de la enfermedad y mantiene una carga viral indetectable incluso ausencia de cualquier terapia antiretroviral. Un caso de gran relevancia para la comunidad científica, dada la rareza de la evolución clínica presentada y la morbilidad y mortalidad de este tipo de infección en Brasil, ya que según datos del Ministerio de Salud el número de infectados se acerca al millón. La posibilidad de control natural de la infección por el virus de la immunodeficiencia humana (VIH) sin el uso de terapia antiretroviral, como la reportada en el caso, abre perspectivas para la comprensión de mecanismos inmunológicos y biomoleculares específicos involucrados en la protección y para la posibilidad de una respuesta espontánea o cura funcional dirigida de la infección.O objetivo do estudo é relatar o caso de um paciente do sexo feminino, com dupla confirmação sorológica em testes rápidos para detecção de anticorpos anti-HIV há mais de 10 anos, em acompanhamento pelo Serviço de Atendimento Especializado/Centro de Testagem e Aconselhamento, que nunca apresentou sinais de progressão clínica da doença e mantém carga viral indetectável mesmo na ausência de qualquer terapia antirretroviral. Caso de grande relevância para a comunidade científica tendo em vista a raridade da evolução clínica apresentada e a morbimortalidade desse tipo de infecção no Brasil, já que segundo dados do Ministério da Saúde o número de infectados aproxima-se de 1 milhão. A possibilidade de controle natural da infecção pelo vírus da imunodeficiência humana (HIV) sem uso de terapia antirretroviral, como a relatada no caso, abre perspectivas para o entendimento de mecanismos imunológicos e biomoleculares específicos envolvidos na proteção e para a possibilidade de uma cura funcional espontânea ou direcionada à infecção.Research, Society and Development2022-08-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3305710.33448/rsd-v11i10.33057Research, Society and Development; Vol. 11 No. 10; e547111033057Research, Society and Development; Vol. 11 Núm. 10; e547111033057Research, Society and Development; v. 11 n. 10; e5471110330572525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/33057/28064Copyright (c) 2022 Iury Venâncio Pinheiro; Heitor Contato Poliseli; Gustavo Marques Costa; Rosana Alves Vieira Carneiro; Cândida Aparecida Leite Kassuyahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPinheiro, Iury VenâncioPoliseli, Heitor Contato Costa, Gustavo Marques Carneiro, Rosana Alves VieiraKassuya, Cândida Aparecida Leite 2022-08-12T22:23:03Zoai:ojs.pkp.sfu.ca:article/33057Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:48:49.970331Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
HIV elite controller: case report Controlador de elite del VIH: informe de un caso HIV controlador de elite: relato de caso |
title |
HIV elite controller: case report |
spellingShingle |
HIV elite controller: case report Pinheiro, Iury Venâncio HIV Anticorpos anti-HIV Portador sadio Síndrome de imunodeficiência adquirida Relatos de casos. VIH Anticuerpos anti-VIH Portador sano Síndrome de inmunodeficiencia adquirida Reporte del caso. HIV HIV antibodies Carrier state Acquired immunodeficiency syndrome Case reports. |
title_short |
HIV elite controller: case report |
title_full |
HIV elite controller: case report |
title_fullStr |
HIV elite controller: case report |
title_full_unstemmed |
HIV elite controller: case report |
title_sort |
HIV elite controller: case report |
author |
Pinheiro, Iury Venâncio |
author_facet |
Pinheiro, Iury Venâncio Poliseli, Heitor Contato Costa, Gustavo Marques Carneiro, Rosana Alves Vieira Kassuya, Cândida Aparecida Leite |
author_role |
author |
author2 |
Poliseli, Heitor Contato Costa, Gustavo Marques Carneiro, Rosana Alves Vieira Kassuya, Cândida Aparecida Leite |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Pinheiro, Iury Venâncio Poliseli, Heitor Contato Costa, Gustavo Marques Carneiro, Rosana Alves Vieira Kassuya, Cândida Aparecida Leite |
dc.subject.por.fl_str_mv |
HIV Anticorpos anti-HIV Portador sadio Síndrome de imunodeficiência adquirida Relatos de casos. VIH Anticuerpos anti-VIH Portador sano Síndrome de inmunodeficiencia adquirida Reporte del caso. HIV HIV antibodies Carrier state Acquired immunodeficiency syndrome Case reports. |
topic |
HIV Anticorpos anti-HIV Portador sadio Síndrome de imunodeficiência adquirida Relatos de casos. VIH Anticuerpos anti-VIH Portador sano Síndrome de inmunodeficiencia adquirida Reporte del caso. HIV HIV antibodies Carrier state Acquired immunodeficiency syndrome Case reports. |
description |
The objective of the study is to report the case of a female patient with double sorological confirmation in rapid tests for anti-HIV antibodies for more 10 years, being follow up by the Service Specialized Attendance/Testing and Counseling Center, who never showed signs of clinical disease progression and maintain an undetectable viral load even in the absence of any antirretroviral therapy. A case of great relevance for the scientific community, given the rarity of the clinical evolution presented and the morbidity and mortality of this type of infection in Brazil, since according to data from the Ministry of Health the number of infected is close to 1 million. The possibility of natural control of human immunodediciency virus (HIV) infection without antiretroviral therapy, such as the one reported in the case, opens perspectives for understanding the specific immunological and biomolecular mechanisms involved in protection and for the possibility of a spontaneous functional cure of the infection. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-08-10 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/33057 10.33448/rsd-v11i10.33057 |
url |
https://rsdjournal.org/index.php/rsd/article/view/33057 |
identifier_str_mv |
10.33448/rsd-v11i10.33057 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/33057/28064 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 10; e547111033057 Research, Society and Development; Vol. 11 Núm. 10; e547111033057 Research, Society and Development; v. 11 n. 10; e547111033057 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052769969897472 |