HIV elite controller: case report

Detalhes bibliográficos
Autor(a) principal: Pinheiro, Iury Venâncio
Data de Publicação: 2022
Outros Autores: Poliseli, Heitor Contato, Costa, Gustavo Marques, Carneiro, Rosana Alves Vieira, Kassuya, Cândida Aparecida Leite
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/33057
Resumo: The objective of the study is to report the case of a female patient with double sorological confirmation in rapid tests for anti-HIV antibodies for more 10 years, being follow up by the Service Specialized Attendance/Testing and Counseling Center, who never showed signs of clinical disease progression and maintain an undetectable viral load even in the absence of any antirretroviral therapy. A case of great relevance for the scientific community, given the rarity of the clinical evolution presented and the morbidity and mortality of this type of infection in Brazil, since according to data from the Ministry of Health the number of infected is close to 1 million. The possibility of natural control of human immunodediciency virus (HIV) infection without antiretroviral therapy, such as the one reported in the case, opens perspectives for understanding the specific immunological and biomolecular mechanisms involved in protection and for the possibility of a spontaneous functional cure of the infection.
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spelling HIV elite controller: case reportControlador de elite del VIH: informe de un caso HIV controlador de elite: relato de casoHIVAnticorpos anti-HIVPortador sadioSíndrome de imunodeficiência adquiridaRelatos de casos.VIHAnticuerpos anti-VIHPortador sanoSíndrome de inmunodeficiencia adquiridaReporte del caso.HIVHIV antibodiesCarrier stateAcquired immunodeficiency syndromeCase reports.The objective of the study is to report the case of a female patient with double sorological confirmation in rapid tests for anti-HIV antibodies for more 10 years, being follow up by the Service Specialized Attendance/Testing and Counseling Center, who never showed signs of clinical disease progression and maintain an undetectable viral load even in the absence of any antirretroviral therapy. A case of great relevance for the scientific community, given the rarity of the clinical evolution presented and the morbidity and mortality of this type of infection in Brazil, since according to data from the Ministry of Health the number of infected is close to 1 million. The possibility of natural control of human immunodediciency virus (HIV) infection without antiretroviral therapy, such as the one reported in the case, opens perspectives for understanding the specific immunological and biomolecular mechanisms involved in protection and for the possibility of a spontaneous functional cure of the infection.El objetivo del estudio es reporte del caso de un paciente femenino, con doble confirmación serológica en pruebas rápidas para detección de anticuerpos anti-VIH desde hace más de 10 años, siendo seguida por el Servicio de Atención Especializada/Centro de Pruebas y Consejería, que nunca mostró signos de progresión clínica de la enfermedad y mantiene una carga viral indetectable incluso ausencia de cualquier terapia antiretroviral. Un caso de gran relevancia para la comunidad científica, dada la rareza de la evolución clínica presentada y la morbilidad y mortalidad de este tipo de infección en Brasil, ya que según datos del Ministerio de Salud el número de infectados se acerca al millón. La posibilidad de control natural de la infección por el virus de la immunodeficiencia humana (VIH) sin el uso de terapia antiretroviral, como la reportada en el caso, abre perspectivas para la comprensión de mecanismos inmunológicos y biomoleculares específicos involucrados en la protección y para la posibilidad de una respuesta espontánea o cura funcional dirigida de la infección.O objetivo do estudo é relatar o caso de um paciente do sexo feminino, com dupla confirmação sorológica em testes rápidos para detecção de anticorpos anti-HIV há mais de 10 anos, em acompanhamento pelo Serviço de Atendimento Especializado/Centro de Testagem e Aconselhamento, que nunca apresentou sinais de progressão clínica da doença e mantém carga viral indetectável mesmo na ausência de qualquer terapia antirretroviral. Caso de grande relevância para a comunidade científica tendo em vista a raridade da evolução clínica apresentada e a morbimortalidade desse tipo de infecção no Brasil, já que segundo dados do Ministério da Saúde o número de infectados aproxima-se de 1 milhão. A possibilidade de controle natural da infecção pelo vírus da imunodeficiência humana (HIV) sem uso de terapia antirretroviral, como a relatada no caso, abre perspectivas para o entendimento de mecanismos imunológicos e biomoleculares específicos envolvidos na proteção e para a possibilidade de uma cura funcional espontânea ou direcionada à infecção.Research, Society and Development2022-08-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3305710.33448/rsd-v11i10.33057Research, Society and Development; Vol. 11 No. 10; e547111033057Research, Society and Development; Vol. 11 Núm. 10; e547111033057Research, Society and Development; v. 11 n. 10; e5471110330572525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/33057/28064Copyright (c) 2022 Iury Venâncio Pinheiro; Heitor Contato Poliseli; Gustavo Marques Costa; Rosana Alves Vieira Carneiro; Cândida Aparecida Leite Kassuyahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPinheiro, Iury VenâncioPoliseli, Heitor Contato Costa, Gustavo Marques Carneiro, Rosana Alves VieiraKassuya, Cândida Aparecida Leite 2022-08-12T22:23:03Zoai:ojs.pkp.sfu.ca:article/33057Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:48:49.970331Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv HIV elite controller: case report
Controlador de elite del VIH: informe de un caso
HIV controlador de elite: relato de caso
title HIV elite controller: case report
spellingShingle HIV elite controller: case report
Pinheiro, Iury Venâncio
HIV
Anticorpos anti-HIV
Portador sadio
Síndrome de imunodeficiência adquirida
Relatos de casos.
VIH
Anticuerpos anti-VIH
Portador sano
Síndrome de inmunodeficiencia adquirida
Reporte del caso.
HIV
HIV antibodies
Carrier state
Acquired immunodeficiency syndrome
Case reports.
title_short HIV elite controller: case report
title_full HIV elite controller: case report
title_fullStr HIV elite controller: case report
title_full_unstemmed HIV elite controller: case report
title_sort HIV elite controller: case report
author Pinheiro, Iury Venâncio
author_facet Pinheiro, Iury Venâncio
Poliseli, Heitor Contato
Costa, Gustavo Marques
Carneiro, Rosana Alves Vieira
Kassuya, Cândida Aparecida Leite
author_role author
author2 Poliseli, Heitor Contato
Costa, Gustavo Marques
Carneiro, Rosana Alves Vieira
Kassuya, Cândida Aparecida Leite
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Pinheiro, Iury Venâncio
Poliseli, Heitor Contato
Costa, Gustavo Marques
Carneiro, Rosana Alves Vieira
Kassuya, Cândida Aparecida Leite
dc.subject.por.fl_str_mv HIV
Anticorpos anti-HIV
Portador sadio
Síndrome de imunodeficiência adquirida
Relatos de casos.
VIH
Anticuerpos anti-VIH
Portador sano
Síndrome de inmunodeficiencia adquirida
Reporte del caso.
HIV
HIV antibodies
Carrier state
Acquired immunodeficiency syndrome
Case reports.
topic HIV
Anticorpos anti-HIV
Portador sadio
Síndrome de imunodeficiência adquirida
Relatos de casos.
VIH
Anticuerpos anti-VIH
Portador sano
Síndrome de inmunodeficiencia adquirida
Reporte del caso.
HIV
HIV antibodies
Carrier state
Acquired immunodeficiency syndrome
Case reports.
description The objective of the study is to report the case of a female patient with double sorological confirmation in rapid tests for anti-HIV antibodies for more 10 years, being follow up by the Service Specialized Attendance/Testing and Counseling Center, who never showed signs of clinical disease progression and maintain an undetectable viral load even in the absence of any antirretroviral therapy. A case of great relevance for the scientific community, given the rarity of the clinical evolution presented and the morbidity and mortality of this type of infection in Brazil, since according to data from the Ministry of Health the number of infected is close to 1 million. The possibility of natural control of human immunodediciency virus (HIV) infection without antiretroviral therapy, such as the one reported in the case, opens perspectives for understanding the specific immunological and biomolecular mechanisms involved in protection and for the possibility of a spontaneous functional cure of the infection.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-10
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33057
10.33448/rsd-v11i10.33057
url https://rsdjournal.org/index.php/rsd/article/view/33057
identifier_str_mv 10.33448/rsd-v11i10.33057
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33057/28064
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 10; e547111033057
Research, Society and Development; Vol. 11 Núm. 10; e547111033057
Research, Society and Development; v. 11 n. 10; e547111033057
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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