Teratogenic agents and fetal development: A narrative review
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/14555 |
Resumo: | Worldwide, according to the Global Report on Congenital Defects, about 7.9 million babies - 6% of all births - have at birth some congenital malformation of genetic or partially genetic origin, while hundreds more are born with developed congenital malformations, preventable causes. The estimated value of the causes of non-genetic malformations is estimated at around 5 to 10%, mainly associated with maternal exposure to teratogenic agents, such as medication, alcohol, tobacco, illicit drugs, microorganisms, radiation, environmental pollution, among others. Thus, this study aimed to identify the influence of some of the main chemical and biological teratogenic agents on congenital malformations, through a narrative literature review. |
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Teratogenic agents and fetal development: A narrative reviewAgentes teratogénicos y desarrollo fetal: Una revisión narrativeAgentes teratogênicos e desenvolvimento fetal: Uma revisão narrativaFetal developmentMaternal and child healthTeratology.Desarrollo fetalSalud maternal e infantilTeratología.Desenvolvimento fetalSaúde materno-infantilTeratologia.Worldwide, according to the Global Report on Congenital Defects, about 7.9 million babies - 6% of all births - have at birth some congenital malformation of genetic or partially genetic origin, while hundreds more are born with developed congenital malformations, preventable causes. The estimated value of the causes of non-genetic malformations is estimated at around 5 to 10%, mainly associated with maternal exposure to teratogenic agents, such as medication, alcohol, tobacco, illicit drugs, microorganisms, radiation, environmental pollution, among others. Thus, this study aimed to identify the influence of some of the main chemical and biological teratogenic agents on congenital malformations, through a narrative literature review.En todo el mundo, según el Informe mundial sobre defectos de nacimiento, alrededor de 7,9 millones de bebés (el 6% de todos los nacimientos) tienen al nacer alguna malformación congénita de origen genético o parcialmente genético, mientras que cientos de miles más nacen con defectos de nacimiento desarrollados, debido a causas prevenibles. El valor estimado de las causas de malformaciones no genéticas se estima en alrededor del 5 al 10%, principalmente asociadas a la exposición materna a agentes teratogénicos, como medicamentos, alcohol, tabaco, drogas ilícitas, microorganismos, radiaciones, contaminación ambiental, entre otros. Así, este estudio tuvo como objetivo identificar la influencia de algunos de los principales agentes teratogénicos químicos y biológicos sobre las malformaciones congénitas, a través de una revisión narrativa de la literatura.Mundialmente, segundo o Global Report on Birth Defects, cerca de 7,9 milhões de bebês – 6% do total de nascimentos – possuem ao nascimento alguma malformação congênita de origem genética ou parcialmente genética, enquanto outras centenas de milhares nascem com malformações congênitas desenvolvidas por causas evitáveis. A prevalência das causas de malformações não-genéticas é estipulada em torno de 5 a 10%, principalmente, associadas à exposição materna a agentes teratogênicos, como medicamentos, álcool, tabaco, drogas ilícitas, micro-organismos, radiação, poluição ambiental, entre outros. Desta forma objetivou-se nesse estudo identificar a influência de alguns dos principais agentes teratogênicos químicos e biológicos nas malformações congênitas, através de uma revisão narrativa de literatura.Research, Society and Development2021-04-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1455510.33448/rsd-v10i5.14555Research, Society and Development; Vol. 10 No. 5; e0210514555Research, Society and Development; Vol. 10 Núm. 5; e0210514555Research, Society and Development; v. 10 n. 5; e02105145552525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/14555/13055Copyright (c) 2021 Maria Eduarda da Silva; Wellington Manoel da Silva; Jardeson Joaquim Bezerra; Joyce Neire Vidal Alexandre Souza; Robert Galvão de Souza; Jéssica dos Santos Costa; Débora Joyce do Nascimento Camilo; Rosivan Sebastião da Silva; Nathália Monteiro da Silva; Núbya Annyédja Marcelino da Silva; Bruno Santos Souza; Barbara Bispo de Santana; Sdnei Gomes dos Santos; Rodrigo Andrade Leal ; Tarcísio Gonçalves de Souza Santos; Maria Hozana Santos Silva ; Lisandra Santana Oliveira Reis; Aranin Queiroz de Sousa Santos ; Marks Passos Santos https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Maria Eduarda daSilva, Wellington Manoel daBezerra, Jardeson Joaquim Souza, Joyce Neire Vidal Alexandre Souza, Robert Galvão de Costa, Jéssica dos Santos Camilo, Débora Joyce do Nascimento Silva, Rosivan Sebastião da Silva, Nathália Monteiro da Silva, Núbya Annyédja Marcelino da Souza, Bruno Santos Santana, Barbara Bispo de Santos, Sdnei Gomes dos Leal , Rodrigo Andrade Santos, Tarcísio Gonçalves de Souza Silva , Maria Hozana Santos Reis, Lisandra Santana Oliveira Santos , Aranin Queiroz de Sousa Santos , Marks Passos2021-05-17T18:20:49Zoai:ojs.pkp.sfu.ca:article/14555Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:35:38.404715Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Teratogenic agents and fetal development: A narrative review Agentes teratogénicos y desarrollo fetal: Una revisión narrative Agentes teratogênicos e desenvolvimento fetal: Uma revisão narrativa |
| title |
Teratogenic agents and fetal development: A narrative review |
| spellingShingle |
Teratogenic agents and fetal development: A narrative review Silva, Maria Eduarda da Fetal development Maternal and child health Teratology. Desarrollo fetal Salud maternal e infantil Teratología. Desenvolvimento fetal Saúde materno-infantil Teratologia. |
| title_short |
Teratogenic agents and fetal development: A narrative review |
| title_full |
Teratogenic agents and fetal development: A narrative review |
| title_fullStr |
Teratogenic agents and fetal development: A narrative review |
| title_full_unstemmed |
Teratogenic agents and fetal development: A narrative review |
| title_sort |
Teratogenic agents and fetal development: A narrative review |
| author |
Silva, Maria Eduarda da |
| author_facet |
Silva, Maria Eduarda da Silva, Wellington Manoel da Bezerra, Jardeson Joaquim Souza, Joyce Neire Vidal Alexandre Souza, Robert Galvão de Costa, Jéssica dos Santos Camilo, Débora Joyce do Nascimento Silva, Rosivan Sebastião da Silva, Nathália Monteiro da Silva, Núbya Annyédja Marcelino da Souza, Bruno Santos Santana, Barbara Bispo de Santos, Sdnei Gomes dos Leal , Rodrigo Andrade Santos, Tarcísio Gonçalves de Souza Silva , Maria Hozana Santos Reis, Lisandra Santana Oliveira Santos , Aranin Queiroz de Sousa Santos , Marks Passos |
| author_role |
author |
| author2 |
Silva, Wellington Manoel da Bezerra, Jardeson Joaquim Souza, Joyce Neire Vidal Alexandre Souza, Robert Galvão de Costa, Jéssica dos Santos Camilo, Débora Joyce do Nascimento Silva, Rosivan Sebastião da Silva, Nathália Monteiro da Silva, Núbya Annyédja Marcelino da Souza, Bruno Santos Santana, Barbara Bispo de Santos, Sdnei Gomes dos Leal , Rodrigo Andrade Santos, Tarcísio Gonçalves de Souza Silva , Maria Hozana Santos Reis, Lisandra Santana Oliveira Santos , Aranin Queiroz de Sousa Santos , Marks Passos |
| author2_role |
author author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Silva, Maria Eduarda da Silva, Wellington Manoel da Bezerra, Jardeson Joaquim Souza, Joyce Neire Vidal Alexandre Souza, Robert Galvão de Costa, Jéssica dos Santos Camilo, Débora Joyce do Nascimento Silva, Rosivan Sebastião da Silva, Nathália Monteiro da Silva, Núbya Annyédja Marcelino da Souza, Bruno Santos Santana, Barbara Bispo de Santos, Sdnei Gomes dos Leal , Rodrigo Andrade Santos, Tarcísio Gonçalves de Souza Silva , Maria Hozana Santos Reis, Lisandra Santana Oliveira Santos , Aranin Queiroz de Sousa Santos , Marks Passos |
| dc.subject.por.fl_str_mv |
Fetal development Maternal and child health Teratology. Desarrollo fetal Salud maternal e infantil Teratología. Desenvolvimento fetal Saúde materno-infantil Teratologia. |
| topic |
Fetal development Maternal and child health Teratology. Desarrollo fetal Salud maternal e infantil Teratología. Desenvolvimento fetal Saúde materno-infantil Teratologia. |
| description |
Worldwide, according to the Global Report on Congenital Defects, about 7.9 million babies - 6% of all births - have at birth some congenital malformation of genetic or partially genetic origin, while hundreds more are born with developed congenital malformations, preventable causes. The estimated value of the causes of non-genetic malformations is estimated at around 5 to 10%, mainly associated with maternal exposure to teratogenic agents, such as medication, alcohol, tobacco, illicit drugs, microorganisms, radiation, environmental pollution, among others. Thus, this study aimed to identify the influence of some of the main chemical and biological teratogenic agents on congenital malformations, through a narrative literature review. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-04-25 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://rsdjournal.org/index.php/rsd/article/view/14555 10.33448/rsd-v10i5.14555 |
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https://rsdjournal.org/index.php/rsd/article/view/14555 |
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10.33448/rsd-v10i5.14555 |
| dc.language.iso.fl_str_mv |
por |
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por |
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https://rsdjournal.org/index.php/rsd/article/view/14555/13055 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development; Vol. 10 No. 5; e0210514555 Research, Society and Development; Vol. 10 Núm. 5; e0210514555 Research, Society and Development; v. 10 n. 5; e0210514555 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
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UNIFEI |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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rsd.articles@gmail.com |
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