Evaluation of the sensitivity profile of Escherichia coli isolated from urinary tract infection to antimicrobials

Detalhes bibliográficos
Autor(a) principal: Cruz, Luisa Ferreira da
Data de Publicação: 2021
Outros Autores: Souza, Israel Lucas Antunes, Souza, Larissa Dias de, Cardoso, Nubia da Silva, Resende, Carlos Ananias Aparecido, Coelho, Gustavo Nogueira, Araújo, Marcelo Gonzaga de Freitas
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/18742
Resumo: The most commonly isolated etiologic agent of urinary tract infections (UTIs) is the bacterium Escherichia coli (E. coli), which accounts for about 40% of cases. As Gram-negative microorganisms, E. coli have a complex cell wall, which is why some antibiotics are less effective when compared to their action against Gram-positive bacteria. Therefore, the objective of this work is to evaluate the sensitivity profile of clinical samples of E. coli bacteria to antimicrobials used in the treatment of UTI through the agar diffusion test. After data collection and analysis, it was possible to observe that most clinical isolates were resistant to amoxicillin and were more sensitive to nitrofurantoin and chloramphenicol. From the information obtained after analyzing the data, it was possible to observe that despite the strict control of the administration of antimicrobial drugs, the incidence of resistant bacteria to such drugs is alarming.
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spelling Evaluation of the sensitivity profile of Escherichia coli isolated from urinary tract infection to antimicrobialsEvaluación del perfil de sensibilidad de Escherichia coli aislada de infección del tracto urinario a los antimicrobianosAvaliação do perfil de sensibilidade de Escherichia coli isoladas de infecção do trato urinário aos antimicrobianosAntimicrobianosEscherichia coliInfección del tracto urinárioPrueba de sensibilidadeResistencia.AntimicrobialsEscherichia coliResistanceSensibility testUrinary Tract infection.AntimicrobianosEscherichia coliInfecção do trato urinárioResistênciaTeste de sensibilidade.The most commonly isolated etiologic agent of urinary tract infections (UTIs) is the bacterium Escherichia coli (E. coli), which accounts for about 40% of cases. As Gram-negative microorganisms, E. coli have a complex cell wall, which is why some antibiotics are less effective when compared to their action against Gram-positive bacteria. Therefore, the objective of this work is to evaluate the sensitivity profile of clinical samples of E. coli bacteria to antimicrobials used in the treatment of UTI through the agar diffusion test. After data collection and analysis, it was possible to observe that most clinical isolates were resistant to amoxicillin and were more sensitive to nitrofurantoin and chloramphenicol. From the information obtained after analyzing the data, it was possible to observe that despite the strict control of the administration of antimicrobial drugs, the incidence of resistant bacteria to such drugs is alarming.El agente etiológico más comúnmente aislado de las infecciones del tracto urinario (ITU) es la bacteria Escherichia coli (E. coli), que representa alrededor del 40% de los casos. Como microorganismos Gram-negativos, E. coli tiene una pared celular compleja, razón por la cual algunos antibióticos son menos efectivos en comparación con su acción contra las bacterias Gram-positivas. Por tanto, el objetivo de este trabajo es evaluar el perfil de sensibilidad de muestras clínicas de la bacteria E. coli a los antimicrobianos utilizados en el tratamiento de las ITU a través de la prueba de difusión en agar. Después de la recopilación y el análisis de los datos, fue posible observar que la mayoría de los aislados clínicos eran resistentes a la amoxicilina y más sensibles a la nitrofurantoína y al cloranfenicol. De la información obtenida luego del análisis de los datos se pudo observar que a pesar del estricto control de la administración de antimicrobianos, la incidencia de bacterias resistentes a dichos fármacos es alarmante.O agente etiológico mais comumente isolado das infecções do trato urinário (ITUs) é a bactéria Escherichia coli (E. coli), a qual é responsável por cerca de 40% dos casos. Sendo microrganismos Gram-negativos, as E. coli possuem uma parede celular complexa, motivo pelo qual alguns antibióticos são menos eficazes quando comparados com sua com sua ação contra bactérias Gram-positivas. Diante disso, o objetivo deste trabalho é avaliar o perfil de sensibilidade de amostras clínicas de bactérias E. coli aos antimicrobianos usados no tratamento da ITU através do teste de difusão em ágar. Após a coleta e análise dos dados foi possível observar que a maioria dos isolados clínicos apresentou resistência a amoxicilina e foram mais sensíveis a nitrofurantoína e a cloranfenicol. A partir das informações obtidas após a análise dos dados foi possível observar que apesar do rígido controle da administração de medicamentos antimicrobianos, a incidência de bactérias resistentes a tais medicamentos é alarmante.Research, Society and Development2021-08-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1874210.33448/rsd-v10i10.18742Research, Society and Development; Vol. 10 No. 10; e184101018742Research, Society and Development; Vol. 10 Núm. 10; e184101018742Research, Society and Development; v. 10 n. 10; e1841010187422525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/18742/16722Copyright (c) 2021 Luisa Ferreira da Cruz; Israel Lucas Antunes Souza; Larissa Dias de Souza; Nubia da Silva Cardoso; Carlos Ananias Aparecido Resende; Gustavo Nogueira Coelho; Marcelo Gonzaga de Freitas Araújohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCruz, Luisa Ferreira da Souza, Israel Lucas Antunes Souza, Larissa Dias deCardoso, Nubia da SilvaResende, Carlos Ananias AparecidoCoelho, Gustavo NogueiraAraújo, Marcelo Gonzaga de Freitas2021-10-02T21:49:16Zoai:ojs.pkp.sfu.ca:article/18742Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:38:48.296295Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Evaluation of the sensitivity profile of Escherichia coli isolated from urinary tract infection to antimicrobials
Evaluación del perfil de sensibilidad de Escherichia coli aislada de infección del tracto urinario a los antimicrobianos
Avaliação do perfil de sensibilidade de Escherichia coli isoladas de infecção do trato urinário aos antimicrobianos
title Evaluation of the sensitivity profile of Escherichia coli isolated from urinary tract infection to antimicrobials
spellingShingle Evaluation of the sensitivity profile of Escherichia coli isolated from urinary tract infection to antimicrobials
Cruz, Luisa Ferreira da
Antimicrobianos
Escherichia coli
Infección del tracto urinário
Prueba de sensibilidade
Resistencia.
Antimicrobials
Escherichia coli
Resistance
Sensibility test
Urinary Tract infection.
Antimicrobianos
Escherichia coli
Infecção do trato urinário
Resistência
Teste de sensibilidade.
title_short Evaluation of the sensitivity profile of Escherichia coli isolated from urinary tract infection to antimicrobials
title_full Evaluation of the sensitivity profile of Escherichia coli isolated from urinary tract infection to antimicrobials
title_fullStr Evaluation of the sensitivity profile of Escherichia coli isolated from urinary tract infection to antimicrobials
title_full_unstemmed Evaluation of the sensitivity profile of Escherichia coli isolated from urinary tract infection to antimicrobials
title_sort Evaluation of the sensitivity profile of Escherichia coli isolated from urinary tract infection to antimicrobials
author Cruz, Luisa Ferreira da
author_facet Cruz, Luisa Ferreira da
Souza, Israel Lucas Antunes
Souza, Larissa Dias de
Cardoso, Nubia da Silva
Resende, Carlos Ananias Aparecido
Coelho, Gustavo Nogueira
Araújo, Marcelo Gonzaga de Freitas
author_role author
author2 Souza, Israel Lucas Antunes
Souza, Larissa Dias de
Cardoso, Nubia da Silva
Resende, Carlos Ananias Aparecido
Coelho, Gustavo Nogueira
Araújo, Marcelo Gonzaga de Freitas
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cruz, Luisa Ferreira da
Souza, Israel Lucas Antunes
Souza, Larissa Dias de
Cardoso, Nubia da Silva
Resende, Carlos Ananias Aparecido
Coelho, Gustavo Nogueira
Araújo, Marcelo Gonzaga de Freitas
dc.subject.por.fl_str_mv Antimicrobianos
Escherichia coli
Infección del tracto urinário
Prueba de sensibilidade
Resistencia.
Antimicrobials
Escherichia coli
Resistance
Sensibility test
Urinary Tract infection.
Antimicrobianos
Escherichia coli
Infecção do trato urinário
Resistência
Teste de sensibilidade.
topic Antimicrobianos
Escherichia coli
Infección del tracto urinário
Prueba de sensibilidade
Resistencia.
Antimicrobials
Escherichia coli
Resistance
Sensibility test
Urinary Tract infection.
Antimicrobianos
Escherichia coli
Infecção do trato urinário
Resistência
Teste de sensibilidade.
description The most commonly isolated etiologic agent of urinary tract infections (UTIs) is the bacterium Escherichia coli (E. coli), which accounts for about 40% of cases. As Gram-negative microorganisms, E. coli have a complex cell wall, which is why some antibiotics are less effective when compared to their action against Gram-positive bacteria. Therefore, the objective of this work is to evaluate the sensitivity profile of clinical samples of E. coli bacteria to antimicrobials used in the treatment of UTI through the agar diffusion test. After data collection and analysis, it was possible to observe that most clinical isolates were resistant to amoxicillin and were more sensitive to nitrofurantoin and chloramphenicol. From the information obtained after analyzing the data, it was possible to observe that despite the strict control of the administration of antimicrobial drugs, the incidence of resistant bacteria to such drugs is alarming.
publishDate 2021
dc.date.none.fl_str_mv 2021-08-08
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/18742
10.33448/rsd-v10i10.18742
url https://rsdjournal.org/index.php/rsd/article/view/18742
identifier_str_mv 10.33448/rsd-v10i10.18742
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/18742/16722
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 10; e184101018742
Research, Society and Development; Vol. 10 Núm. 10; e184101018742
Research, Society and Development; v. 10 n. 10; e184101018742
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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