Changes in enamel surface after use of nanoencapsulated fluoride for dental caries remineralization: an in vitro study

Detalhes bibliográficos
Autor(a) principal: Cunha, Juliellen Luiz da
Data de Publicação: 2022
Outros Autores: Sousa, Elizabeth Barreto Galvão de, Fernandes, Nayanna Lana Soares, Meira, Ingrid Andrade, Lavôr, Juliane Rolim de, Vieira, Thiago Isidro, Pereira, Ana Maria Barros Chaves, Sampaio, Fabio Correia, Oliveira, Andressa Feitosa Bezerra de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/26176
Resumo: Aim: To evaluate through an in vitro study surface changes on decayed enamel after the use of fluoridated dentifrices involving nanoencapsulated technology (NanoF). Methods: Forty blocks of human enamel were distributed among four groups (n = 10): 50% NanoF + 50% NaF (50% nF), 100% NanoF (100% nF), 100% NaF as the positive control (PC) and without fluoride as the negative control (NC). The specimens were subjected to a pH cycling model for 7 days. Surface microhardness (SMH), linear surface roughness (Ra) and area surface roughness (Sa) were measured before and after the carious lesion formation and at the end of the treatment. Percentages of surface microhardness recovery (%SMHR), altered Ra (%RaC) and altered Sa (%SaC) were calculated. The data were analyzed using the ANOVA test, repeated-measures ANOVA and Pearson's correlation test (p<0.05). Results: No significant differences among groups were found for Ra, Sa, %RaC or %SaC (p>0.05). Ra and Sa increased after treatment. A significant correlation was found between Ra and Sa. The PC dentifrice had the highest %SMHR, followed by 100% nF (p<0.05). In contrast, no surface remineralization was found in the 50% nF and NC groups. Conclusion: Enamel surface changes were found after the remineralizing treatment with 100% nF group. The majority of dentifrices with fluoride provided an increase in the roughness and surface microhardness. Nanotechnology is an innovative, promising method for the controlled release of fluoride and the remineralization of teeth with dental caries.
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spelling Changes in enamel surface after use of nanoencapsulated fluoride for dental caries remineralization: an in vitro study Cambios en la superficie del esmalte después del uso de flúor nanoencapsulado para la remineralización de caries dental: un estudio in vitroAlterações na superfície do esmalte após uso de flúor nanoencapsulado para remineralização da cárie dentária: um estudo in vitroCremes dentaisRemineralização dentáriaCárie dentáriaFlúorNanotecnologia.Dental cariesToothpastesTooth remineralizationFluorideNanotechnology.Remineralización dentalCaries dentalPasta de dientesFlúorNanotecnología.Aim: To evaluate through an in vitro study surface changes on decayed enamel after the use of fluoridated dentifrices involving nanoencapsulated technology (NanoF). Methods: Forty blocks of human enamel were distributed among four groups (n = 10): 50% NanoF + 50% NaF (50% nF), 100% NanoF (100% nF), 100% NaF as the positive control (PC) and without fluoride as the negative control (NC). The specimens were subjected to a pH cycling model for 7 days. Surface microhardness (SMH), linear surface roughness (Ra) and area surface roughness (Sa) were measured before and after the carious lesion formation and at the end of the treatment. Percentages of surface microhardness recovery (%SMHR), altered Ra (%RaC) and altered Sa (%SaC) were calculated. The data were analyzed using the ANOVA test, repeated-measures ANOVA and Pearson's correlation test (p<0.05). Results: No significant differences among groups were found for Ra, Sa, %RaC or %SaC (p>0.05). Ra and Sa increased after treatment. A significant correlation was found between Ra and Sa. The PC dentifrice had the highest %SMHR, followed by 100% nF (p<0.05). In contrast, no surface remineralization was found in the 50% nF and NC groups. Conclusion: Enamel surface changes were found after the remineralizing treatment with 100% nF group. The majority of dentifrices with fluoride provided an increase in the roughness and surface microhardness. Nanotechnology is an innovative, promising method for the controlled release of fluoride and the remineralization of teeth with dental caries.Objetivo: Evaluar por medio de un estudio in vitro los cambios en la superficie del esmalte cariado tras el uso de dentífricos fluorados con tecnología nanoencapsulada (NanoF). Métodos: Se distribuyeron 40 bloques de esmalte humano en cuatro grupos (n = 10): 50% NanoF + 50% NaF (50% nF), 100% NanoF (100% nF), 100% NaF como control positivo (CP) y sin flúor como control negativo (CN). Las muestras se sometieron a un modelo de ciclos de pH durante 7 días. Se midieron la microdureza superficial (SMH), la rugosidad superficial lineal (Ra) y la rugosidad de área superficial (Sa) antes y después de la formación de la lesión cariada y al final del tratamiento. Se calcularon los porcentajes de recuperación de la microdureza superficial (%SMHR), Ra alterada (%RaC) y Sa alterada (%SaC). Los datos se analizaron mediante la prueba ANOVA, ANOVA de medidas repetidas y la prueba de correlación de Pearson (p<0,05). Resultados: No se encontraron diferencias significativas entre los grupos para Ra, Sa, %RaC o %SaC (p>0,05). Ra y Sa aumentaron después del tratamiento. Se encontró una correlación significativa entre Ra y Sa. El CP tuvo el mayor %SMHR, seguido del 100% nF (p<0,05). Por el contrario, no se encontró remineralización superficial en los grupos de 50% nF y CN. Conclusión: Se encontraron cambios en la superficie del esmalte tras el tratamiento remineralizador con el grupo de 100% nF. La mayoría de los dentífricos con flúor proporcionaron un aumento de la rugosidad y la microdureza superficial. La nanotecnología es un método innovador y prometedor para la liberación controlada de flúor y en la remineralización de dientes con caries dental.Objetivo: Avaliar por meio de um estudo in vitro as mudanças superficiais no esmalte cariado após o uso de dentifrícios fluoretados envolvendo tecnologia nanoencapsulada (NanoF). Métodos: Quarenta blocos de esmalte humano foram distribuídos em quatro grupos (n = 10): 50% NanoF + 50% NaF (50% nF), 100% NanoF (100% nF), 100% NaF como controle positivo (CP) e sem flúor como controle negativo (CN). As amostras foram submetidas a um modelo de ciclagem de pH durante 7 dias. A microdureza superficial (SMH), a rugosidade linear da superfície (Ra) e a rugosidade da área superficial (Sa) foram medidas antes e depois da formação da lesão cariosa e ao final do tratamento. Foram calculadas as porcentagens de recuperação da microdureza superficial (%SMHR), Ra (%RaC) alterada e Sa (%SaC) alterada. Os dados foram analisados utilizando o teste ANOVA, ANOVA de medidas repetidas e o teste de correlação de Pearson (p<0,05). Resultados: Não foram encontradas diferenças significativas entre os grupos para Ra, Sa, %RaC ou %SaC (p>0,05). Ra e Sa aumentaram após o tratamento. Foi encontrada uma correlação significativa entre Ra e Sa. O CP teve a maior %SMHR, seguido por 100% nF (p<0,05). Em contraste, não foi encontrada remineralização de superfície nos grupos 50% nF e CN. Conclusão: Foram encontradas alterações na superfície do esmalte após o tratamento remineralizante com o grupo 100% nF. A maioria dos dentifrícios com flúor proporcionou um aumento na rugosidade e microdureza superficial. A nanotecnologia é um método inovador e promissor para a liberação controlada do flúor e na remineralização dos dentes com cárie dentária.Research, Society and Development2022-03-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2617610.33448/rsd-v11i4.26176Research, Society and Development; Vol. 11 No. 4; e7611426176Research, Society and Development; Vol. 11 Núm. 4; e7611426176Research, Society and Development; v. 11 n. 4; e76114261762525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/26176/24215Copyright (c) 2022 Juliellen Luiz da Cunha; Elizabeth Barreto Galvão de Sousa; Nayanna Lana Soares Fernandes; Ingrid Andrade Meira; Juliane Rolim de Lavôr; Thiago Isidro Vieira; Ana Maria Barros Chaves Pereira; Fabio Correia Sampaio; Andressa Feitosa Bezerra de Oliveirahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCunha, Juliellen Luiz da Sousa, Elizabeth Barreto Galvão de Fernandes, Nayanna Lana SoaresMeira, Ingrid AndradeLavôr, Juliane Rolim deVieira, Thiago IsidroPereira, Ana Maria Barros ChavesSampaio, Fabio Correia Oliveira, Andressa Feitosa Bezerra de 2022-03-27T17:17:09Zoai:ojs.pkp.sfu.ca:article/26176Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:16.917757Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Changes in enamel surface after use of nanoencapsulated fluoride for dental caries remineralization: an in vitro study
Cambios en la superficie del esmalte después del uso de flúor nanoencapsulado para la remineralización de caries dental: un estudio in vitro
Alterações na superfície do esmalte após uso de flúor nanoencapsulado para remineralização da cárie dentária: um estudo in vitro
title Changes in enamel surface after use of nanoencapsulated fluoride for dental caries remineralization: an in vitro study
spellingShingle Changes in enamel surface after use of nanoencapsulated fluoride for dental caries remineralization: an in vitro study
Cunha, Juliellen Luiz da
Cremes dentais
Remineralização dentária
Cárie dentária
Flúor
Nanotecnologia.
Dental caries
Toothpastes
Tooth remineralization
Fluoride
Nanotechnology.
Remineralización dental
Caries dental
Pasta de dientes
Flúor
Nanotecnología.
title_short Changes in enamel surface after use of nanoencapsulated fluoride for dental caries remineralization: an in vitro study
title_full Changes in enamel surface after use of nanoencapsulated fluoride for dental caries remineralization: an in vitro study
title_fullStr Changes in enamel surface after use of nanoencapsulated fluoride for dental caries remineralization: an in vitro study
title_full_unstemmed Changes in enamel surface after use of nanoencapsulated fluoride for dental caries remineralization: an in vitro study
title_sort Changes in enamel surface after use of nanoencapsulated fluoride for dental caries remineralization: an in vitro study
author Cunha, Juliellen Luiz da
author_facet Cunha, Juliellen Luiz da
Sousa, Elizabeth Barreto Galvão de
Fernandes, Nayanna Lana Soares
Meira, Ingrid Andrade
Lavôr, Juliane Rolim de
Vieira, Thiago Isidro
Pereira, Ana Maria Barros Chaves
Sampaio, Fabio Correia
Oliveira, Andressa Feitosa Bezerra de
author_role author
author2 Sousa, Elizabeth Barreto Galvão de
Fernandes, Nayanna Lana Soares
Meira, Ingrid Andrade
Lavôr, Juliane Rolim de
Vieira, Thiago Isidro
Pereira, Ana Maria Barros Chaves
Sampaio, Fabio Correia
Oliveira, Andressa Feitosa Bezerra de
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cunha, Juliellen Luiz da
Sousa, Elizabeth Barreto Galvão de
Fernandes, Nayanna Lana Soares
Meira, Ingrid Andrade
Lavôr, Juliane Rolim de
Vieira, Thiago Isidro
Pereira, Ana Maria Barros Chaves
Sampaio, Fabio Correia
Oliveira, Andressa Feitosa Bezerra de
dc.subject.por.fl_str_mv Cremes dentais
Remineralização dentária
Cárie dentária
Flúor
Nanotecnologia.
Dental caries
Toothpastes
Tooth remineralization
Fluoride
Nanotechnology.
Remineralización dental
Caries dental
Pasta de dientes
Flúor
Nanotecnología.
topic Cremes dentais
Remineralização dentária
Cárie dentária
Flúor
Nanotecnologia.
Dental caries
Toothpastes
Tooth remineralization
Fluoride
Nanotechnology.
Remineralización dental
Caries dental
Pasta de dientes
Flúor
Nanotecnología.
description Aim: To evaluate through an in vitro study surface changes on decayed enamel after the use of fluoridated dentifrices involving nanoencapsulated technology (NanoF). Methods: Forty blocks of human enamel were distributed among four groups (n = 10): 50% NanoF + 50% NaF (50% nF), 100% NanoF (100% nF), 100% NaF as the positive control (PC) and without fluoride as the negative control (NC). The specimens were subjected to a pH cycling model for 7 days. Surface microhardness (SMH), linear surface roughness (Ra) and area surface roughness (Sa) were measured before and after the carious lesion formation and at the end of the treatment. Percentages of surface microhardness recovery (%SMHR), altered Ra (%RaC) and altered Sa (%SaC) were calculated. The data were analyzed using the ANOVA test, repeated-measures ANOVA and Pearson's correlation test (p<0.05). Results: No significant differences among groups were found for Ra, Sa, %RaC or %SaC (p>0.05). Ra and Sa increased after treatment. A significant correlation was found between Ra and Sa. The PC dentifrice had the highest %SMHR, followed by 100% nF (p<0.05). In contrast, no surface remineralization was found in the 50% nF and NC groups. Conclusion: Enamel surface changes were found after the remineralizing treatment with 100% nF group. The majority of dentifrices with fluoride provided an increase in the roughness and surface microhardness. Nanotechnology is an innovative, promising method for the controlled release of fluoride and the remineralization of teeth with dental caries.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-27
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/26176
10.33448/rsd-v11i4.26176
url https://rsdjournal.org/index.php/rsd/article/view/26176
identifier_str_mv 10.33448/rsd-v11i4.26176
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/26176/24215
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 4; e7611426176
Research, Society and Development; Vol. 11 Núm. 4; e7611426176
Research, Society and Development; v. 11 n. 4; e7611426176
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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