Chemical characterization of a glycosylated cyanidin obtained from Kalanchoe laetivirens extracts and evaluation of its antimicrobial potential

Detalhes bibliográficos
Autor(a) principal: Ferreira, Deuzilene da Silva
Data de Publicação: 2021
Outros Autores: Santiago, Paulo Alexandre Lima, Ribeiro de Lima, Bruna, Soares, Elzalina Ribeiro, Almeida, Richardson Alves de, Christine Ohse, Ketlen, Cruz, Alessandra de Oliveira, Santiago, Sarah Raquel Silveira da Silva
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/21483
Resumo: The species Kalanchoe laetivirens is a succulent from tropical areas such as Africa and Asia. Due to the favorable climate, this plant was introduced in Brazil where it is used as a medicinal alternative for the treatment of diseases such as infections, inflammations, diarrhea and wound healing. The compounds present in this organism belong, for the most part, to the class of flavonoids with antioxidant, gastroprotective, antiulcer, kidney stones, bacterial and viral infections. Thus, the objective of this work was to investigate the chemical compounds present in crude extracts and their fractions, as well as to verify their antimicrobial potential. For this, the plant sample was subjected to extraction with 70% ethanol and then fractionated with hexane, chloroform and ethyl acetate. Such extracts were analyzed in high performance liquid chromatography coupled to a mass spectrometer to verify the ions present in the samples. 3,7-di-O-rhamnosyl-cyanidin was found to be a glycosylated cyanidin. Its antimicrobial activity was determined to be negative against the tested pathogens.
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spelling Chemical characterization of a glycosylated cyanidin obtained from Kalanchoe laetivirens extracts and evaluation of its antimicrobial potentialCaracterización química de una cianidina glicosilada obtenida de extractos de Kalanchoe laetivirens y evaluación de su potencial antimicrobianoCaracterização química de uma cianidina glicosilada obtida a partir dos extratos de Kalanchoe laetivirens e avaliação do seu potencial antimicrobiano Plantas medicinalesCianidinaAntimicrobiano.Plantas medicinaisCianidinAntimicrobiano.Medicinal plantsCyanidinAntimicrobial.The species Kalanchoe laetivirens is a succulent from tropical areas such as Africa and Asia. Due to the favorable climate, this plant was introduced in Brazil where it is used as a medicinal alternative for the treatment of diseases such as infections, inflammations, diarrhea and wound healing. The compounds present in this organism belong, for the most part, to the class of flavonoids with antioxidant, gastroprotective, antiulcer, kidney stones, bacterial and viral infections. Thus, the objective of this work was to investigate the chemical compounds present in crude extracts and their fractions, as well as to verify their antimicrobial potential. For this, the plant sample was subjected to extraction with 70% ethanol and then fractionated with hexane, chloroform and ethyl acetate. Such extracts were analyzed in high performance liquid chromatography coupled to a mass spectrometer to verify the ions present in the samples. 3,7-di-O-rhamnosyl-cyanidin was found to be a glycosylated cyanidin. Its antimicrobial activity was determined to be negative against the tested pathogens.La especie Kalanchoe laetivirens es una suculenta de áreas tropicales como África y Asia. Debido al clima favorable, esta planta fue introducida en Brasil donde se utiliza como alternativa medicinal para el tratamiento de enfermedades como infecciones, inflamaciones, diarreas y cicatrización de heridas. Los compuestos presentes en este organismo pertenecen, en su mayor parte, a la clase de flavonoides con antioxidantes, gastroprotectores, antiulcerosos, cálculos renales, infecciones bacterianas y virales. Así, el objetivo de este trabajo fue investigar los compuestos químicos presentes en los extractos crudos y sus fracciones, así como verificar su potencial antimicrobiano. Para ello, la muestra de la planta se sometió a extracción con etanol al 70% y luego se fraccionó con hexano, cloroformo y acetato de etilo. Dichos extractos se analizaron en cromatografía líquida de alta resolución acoplada a un espectrómetro de masas para verificar los iones presentes en las muestras. Se encontró que la 3,7-di-O-ramnosil-cianidina era una cianidina glicosilada. Se determinó que su actividad antimicrobiana era negativa frente a los patógenos probados.A espécie Kalanchoe laetivirens é uma suculenta proveniente de áreas tropicais como a África e Ásia. Devido ao clima favorável, esta planta foi introduzida no Brazil onde é utilizada como alternativa medicinal para o tratamento de doenças como infecções, inflamações, diarréia e cicatrização de ferimentos. Os compostos presentes neste organismo pertencem, em sua grande maioria, a classe dos flavonoides com atividades antioxidante, gastroprotetora, antiúlcera, cálculos renais, infecções bacterianas e virais. Sendo assim, o objetivo deste trabalho foi investigar os compostos químicos presentes nos extratos brutos e das suas frações bem como verificar seu potencial antimicrobiano. Para isso, a amostra vegetal foi submetida à extração com etanol 70% sendo fracionada em seguida com hexano, clorofórmio e acetato de etila. Tais extratos foram analisados em cromatografia líquida de alta eficiência acoplada ao espectrômetro de massas para verificar os íons presentes nas amostras. Foi encontrado composto 3,7-di-O-ramnosil-cianidina, a uma cianidina glicosilada. Sua atividade antimicrobiana foi determinada como sendo negativa frente aos patógenos testados.Research, Society and Development2021-11-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2148310.33448/rsd-v10i14.21483Research, Society and Development; Vol. 10 No. 14; e345101421483Research, Society and Development; Vol. 10 Núm. 14; e345101421483Research, Society and Development; v. 10 n. 14; e3451014214832525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/21483/19948Copyright (c) 2021 Deuzilene da Silva Ferreira; Paulo Alexandre Lima Santiago; Bruna Ribeiro de Lima; Elzalina Ribeiro Soares; Richardson Alves de Almeida; Ketlen Christine Ohse; Alessandra de Oliveira Cruz; Sarah Raquel Silveira da Silva Santiagohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFerreira, Deuzilene da Silva Santiago, Paulo Alexandre Lima Ribeiro de Lima, Bruna Soares, Elzalina Ribeiro Almeida, Richardson Alves de Christine Ohse, Ketlen Cruz, Alessandra de Oliveira Santiago, Sarah Raquel Silveira da Silva 2021-12-04T11:48:39Zoai:ojs.pkp.sfu.ca:article/21483Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:40:53.181339Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Chemical characterization of a glycosylated cyanidin obtained from Kalanchoe laetivirens extracts and evaluation of its antimicrobial potential
Caracterización química de una cianidina glicosilada obtenida de extractos de Kalanchoe laetivirens y evaluación de su potencial antimicrobiano
Caracterização química de uma cianidina glicosilada obtida a partir dos extratos de Kalanchoe laetivirens e avaliação do seu potencial antimicrobiano
title Chemical characterization of a glycosylated cyanidin obtained from Kalanchoe laetivirens extracts and evaluation of its antimicrobial potential
spellingShingle Chemical characterization of a glycosylated cyanidin obtained from Kalanchoe laetivirens extracts and evaluation of its antimicrobial potential
Ferreira, Deuzilene da Silva
Plantas medicinales
Cianidina
Antimicrobiano.
Plantas medicinais
Cianidin
Antimicrobiano.
Medicinal plants
Cyanidin
Antimicrobial.
title_short Chemical characterization of a glycosylated cyanidin obtained from Kalanchoe laetivirens extracts and evaluation of its antimicrobial potential
title_full Chemical characterization of a glycosylated cyanidin obtained from Kalanchoe laetivirens extracts and evaluation of its antimicrobial potential
title_fullStr Chemical characterization of a glycosylated cyanidin obtained from Kalanchoe laetivirens extracts and evaluation of its antimicrobial potential
title_full_unstemmed Chemical characterization of a glycosylated cyanidin obtained from Kalanchoe laetivirens extracts and evaluation of its antimicrobial potential
title_sort Chemical characterization of a glycosylated cyanidin obtained from Kalanchoe laetivirens extracts and evaluation of its antimicrobial potential
author Ferreira, Deuzilene da Silva
author_facet Ferreira, Deuzilene da Silva
Santiago, Paulo Alexandre Lima
Ribeiro de Lima, Bruna
Soares, Elzalina Ribeiro
Almeida, Richardson Alves de
Christine Ohse, Ketlen
Cruz, Alessandra de Oliveira
Santiago, Sarah Raquel Silveira da Silva
author_role author
author2 Santiago, Paulo Alexandre Lima
Ribeiro de Lima, Bruna
Soares, Elzalina Ribeiro
Almeida, Richardson Alves de
Christine Ohse, Ketlen
Cruz, Alessandra de Oliveira
Santiago, Sarah Raquel Silveira da Silva
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Ferreira, Deuzilene da Silva
Santiago, Paulo Alexandre Lima
Ribeiro de Lima, Bruna
Soares, Elzalina Ribeiro
Almeida, Richardson Alves de
Christine Ohse, Ketlen
Cruz, Alessandra de Oliveira
Santiago, Sarah Raquel Silveira da Silva
dc.subject.por.fl_str_mv Plantas medicinales
Cianidina
Antimicrobiano.
Plantas medicinais
Cianidin
Antimicrobiano.
Medicinal plants
Cyanidin
Antimicrobial.
topic Plantas medicinales
Cianidina
Antimicrobiano.
Plantas medicinais
Cianidin
Antimicrobiano.
Medicinal plants
Cyanidin
Antimicrobial.
description The species Kalanchoe laetivirens is a succulent from tropical areas such as Africa and Asia. Due to the favorable climate, this plant was introduced in Brazil where it is used as a medicinal alternative for the treatment of diseases such as infections, inflammations, diarrhea and wound healing. The compounds present in this organism belong, for the most part, to the class of flavonoids with antioxidant, gastroprotective, antiulcer, kidney stones, bacterial and viral infections. Thus, the objective of this work was to investigate the chemical compounds present in crude extracts and their fractions, as well as to verify their antimicrobial potential. For this, the plant sample was subjected to extraction with 70% ethanol and then fractionated with hexane, chloroform and ethyl acetate. Such extracts were analyzed in high performance liquid chromatography coupled to a mass spectrometer to verify the ions present in the samples. 3,7-di-O-rhamnosyl-cyanidin was found to be a glycosylated cyanidin. Its antimicrobial activity was determined to be negative against the tested pathogens.
publishDate 2021
dc.date.none.fl_str_mv 2021-11-15
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/21483
10.33448/rsd-v10i14.21483
url https://rsdjournal.org/index.php/rsd/article/view/21483
identifier_str_mv 10.33448/rsd-v10i14.21483
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/21483/19948
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 14; e345101421483
Research, Society and Development; Vol. 10 Núm. 14; e345101421483
Research, Society and Development; v. 10 n. 14; e345101421483
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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