Secondary metabolites with antitumor activity: a review
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/26786 |
Resumo: | Cancer is a disease that presents as its main characteristic the uncontrolled growth of cells, which is currently numerous people annually. The available treatments such as chemotherapy cause many adverse effects in cancer patients because it also reaches the viable cells of the body. Plants have a wide variety of pharmacologically active compounds and are major sources for the development of new drugs with oncological potential. Biodiversity has been prospected in recent decades to discover and develop new drugs that are safer and more effective in the battle against cancer, acting more selectively with fewer toxic effects. Some drugs currently used in cancer treatment are derived from plants. Therefore, the present review aimed to address the general aspects of cancer and the pharmacological potential of secondary metabolites in cancer treatment. Through the bibliographic survey, it is concluded that there is much to be explored and plants present numerous therapeutic possibilities. |
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Secondary metabolites with antitumor activity: a reviewMetabolitos secundarios con actividad antitumoral: una reseñaMetabólitos secundários com atividade antitumoral: uma revisãoBiodiversidadCáncerCompuestos activosPlantas medicinalesVariedad estructural. BiodiversidadeCâncerCompostos ativosPlantas medicinaisVariedade estrutural. BiodiversityCancerActive compoundsMedicinal plantsStructural variety. Cancer is a disease that presents as its main characteristic the uncontrolled growth of cells, which is currently numerous people annually. The available treatments such as chemotherapy cause many adverse effects in cancer patients because it also reaches the viable cells of the body. Plants have a wide variety of pharmacologically active compounds and are major sources for the development of new drugs with oncological potential. Biodiversity has been prospected in recent decades to discover and develop new drugs that are safer and more effective in the battle against cancer, acting more selectively with fewer toxic effects. Some drugs currently used in cancer treatment are derived from plants. Therefore, the present review aimed to address the general aspects of cancer and the pharmacological potential of secondary metabolites in cancer treatment. Through the bibliographic survey, it is concluded that there is much to be explored and plants present numerous therapeutic possibilities.Cáncer, una enfermedad que presenta como principal característica el crecimiento descontrolado de células, que actualmente es de numerosas personas anualmente. Los tratamientos disponibles como la quimioterapia causan muchos efectos adversos en pacientes con cáncer, debido al hecho de que también llega a las células viables del cuerpo. Las plantas tienen una amplia variedad de compuestos farmacológicamente activos y son fuentes importantes para el desarrollo de nuevos fármacos con potencial oncológico. La biodiversidad ha sido bioprospeccionada en las últimas décadas con el fin de descubrir y desarrollar nuevos fármacos que sean más seguros y eficaces en la lucha contra el cáncer, actuando de forma más selectiva con menos efectos tóxicos. Algunos medicamentos que se usan actualmente en el tratamiento del cáncer se derivan de las plantas. Por lo tanto, la presente revisión tuvo como objetivo abordar los aspectos generales del cáncer y el potencial farmacológico de los metabolitos secundarios en el tratamiento del cáncer. A través de la encuesta bibliográfica, se concluye que hay mucho por explorar y las plantas presentan numerosas posibilidades terapéuticas.O câncer, uma doença que apresenta como principal característica o crescimento descontrolado das células, essa acomete inúmeras pessoas anualmente. Os tratamentos disponíveis como a quimioterapia causam muitos efeitos adversos em pacientes oncológicos, devido ao fato de atingir também as células viáveis do organismo. As plantas dispõem de uma grande variedade de compostos ativos farmacologicamente e são grandes fontes para o desenvolvimento de novos fármacos com potencial oncológico. A biodiversidade vem sendo bioprospectada nas últimas décadas com a finalidade de descobrir e desenvolver novos fármacos mais seguros e efetivos na batalha contra o câncer, atuando de maneira mais seletiva com menos efeitos tóxicos. Alguns fármacos utilizados atualmente no tratamento do câncer são derivados de plantas. Portanto, a presente revisão objetivou abordar os aspectos gerais do câncer e o potencial farmacológico dos metabólitos secundários no tratamento oncológico. Através do levantamento bibliográfico, conclui-se que há muito que ser explorado e as plantas apresentam inúmeras possibilidades terapêuticas.Research, Society and Development2022-03-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2678610.33448/rsd-v11i3.26786Research, Society and Development; Vol. 11 No. 3; e49511326786Research, Society and Development; Vol. 11 Núm. 3; e49511326786Research, Society and Development; v. 11 n. 3; e495113267862525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/26786/23473Copyright (c) 2022 Ana Carolina Sebastião Serra ; Nicole dos Santos Vilela de Souza ; Gabrielly da Silva Paes; Ludovico Migliolo; Lilliam May Grespan Estodutto da Silvahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSerra , Ana Carolina Sebastião Souza , Nicole dos Santos Vilela de Paes, Gabrielly da Silva Migliolo, LudovicoSilva, Lilliam May Grespan Estodutto da 2022-03-09T13:44:38Zoai:ojs.pkp.sfu.ca:article/26786Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:44.483511Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Secondary metabolites with antitumor activity: a review Metabolitos secundarios con actividad antitumoral: una reseña Metabólitos secundários com atividade antitumoral: uma revisão |
| title |
Secondary metabolites with antitumor activity: a review |
| spellingShingle |
Secondary metabolites with antitumor activity: a review Serra , Ana Carolina Sebastião Biodiversidad Cáncer Compuestos activos Plantas medicinales Variedad estructural. Biodiversidade Câncer Compostos ativos Plantas medicinais Variedade estrutural. Biodiversity Cancer Active compounds Medicinal plants Structural variety. |
| title_short |
Secondary metabolites with antitumor activity: a review |
| title_full |
Secondary metabolites with antitumor activity: a review |
| title_fullStr |
Secondary metabolites with antitumor activity: a review |
| title_full_unstemmed |
Secondary metabolites with antitumor activity: a review |
| title_sort |
Secondary metabolites with antitumor activity: a review |
| author |
Serra , Ana Carolina Sebastião |
| author_facet |
Serra , Ana Carolina Sebastião Souza , Nicole dos Santos Vilela de Paes, Gabrielly da Silva Migliolo, Ludovico Silva, Lilliam May Grespan Estodutto da |
| author_role |
author |
| author2 |
Souza , Nicole dos Santos Vilela de Paes, Gabrielly da Silva Migliolo, Ludovico Silva, Lilliam May Grespan Estodutto da |
| author2_role |
author author author author |
| dc.contributor.author.fl_str_mv |
Serra , Ana Carolina Sebastião Souza , Nicole dos Santos Vilela de Paes, Gabrielly da Silva Migliolo, Ludovico Silva, Lilliam May Grespan Estodutto da |
| dc.subject.por.fl_str_mv |
Biodiversidad Cáncer Compuestos activos Plantas medicinales Variedad estructural. Biodiversidade Câncer Compostos ativos Plantas medicinais Variedade estrutural. Biodiversity Cancer Active compounds Medicinal plants Structural variety. |
| topic |
Biodiversidad Cáncer Compuestos activos Plantas medicinales Variedad estructural. Biodiversidade Câncer Compostos ativos Plantas medicinais Variedade estrutural. Biodiversity Cancer Active compounds Medicinal plants Structural variety. |
| description |
Cancer is a disease that presents as its main characteristic the uncontrolled growth of cells, which is currently numerous people annually. The available treatments such as chemotherapy cause many adverse effects in cancer patients because it also reaches the viable cells of the body. Plants have a wide variety of pharmacologically active compounds and are major sources for the development of new drugs with oncological potential. Biodiversity has been prospected in recent decades to discover and develop new drugs that are safer and more effective in the battle against cancer, acting more selectively with fewer toxic effects. Some drugs currently used in cancer treatment are derived from plants. Therefore, the present review aimed to address the general aspects of cancer and the pharmacological potential of secondary metabolites in cancer treatment. Through the bibliographic survey, it is concluded that there is much to be explored and plants present numerous therapeutic possibilities. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-03-04 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/26786 10.33448/rsd-v11i3.26786 |
| url |
https://rsdjournal.org/index.php/rsd/article/view/26786 |
| identifier_str_mv |
10.33448/rsd-v11i3.26786 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/26786/23473 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Research, Society and Development |
| publisher.none.fl_str_mv |
Research, Society and Development |
| dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 3; e49511326786 Research, Society and Development; Vol. 11 Núm. 3; e49511326786 Research, Society and Development; v. 11 n. 3; e49511326786 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
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UNIFEI |
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UNIFEI |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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rsd.articles@gmail.com |
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1797052826535329792 |