Use of curcumin in the treatment of Ulcerative Colitis

• Autor(a) principal: Marques Santos, Carlos Henrique
• Data de Publicação: 2022
• Outros Autores: Marques Torresilha, Ana Luísa, Momm, Gabriela Cruz, Yamaki, Giovanna Larsen, Souza, Matheus Santana de, Castilho, Newton Signorini, Teles Vieira, Stéfany
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/28480
• topic: Colite Ulcerativa; Curcumina; Cúrcuma; Ensino de saúde.; Colitis Ulcerosa; Curcumina; Curcuma; Educacion en la salud.; Colitis Ulcerative; Curcumin; Curcuma; Health teaching.

The present study is a literary review on the use of curcumin in the treatment of ulcerative colitis (UC), a chronic inflammatory bowel disease (IBD), which has as clinical manifestations diarrhea and hematochezia. We sought to gather data from clinical trials, experimental studies and literary reviews, on turmeric therapy in the treatment of UC compared to conventional treatment have seen the increased incidence of IBD and its high drug cost. Curcumin, one of the active ingredients of this herbal medicine, has an anti-inflammatory effect previously observed in other conditions, and demonstrated efficacy in clinical remission of UC in animal models and as adjunct therapy to standard treatment in humans, reducing its chances of recurrence and the risk of developing dysplasia and neoplasms, as well as endoscopic improvement and intestinal motility, which added to the absence of important adverse effects is unique for improving the quality of life of patients with UC who make their use. Thus, it is important to recognize turmeric as an alternative therapy and encourage further studies addressing its use in the treatment of UC, since it is a widely available herbal medicine in our environment and has great medicinal potential.