Seroprevalence of the Human T Lymphotropic Virus (HTLV 1 and HTLV 2) in Blood Donor Candidates in the State of Pará, Northern Brazil

Detalhes bibliográficos
Autor(a) principal: Maneschy, Carolina de Alcântara
Data de Publicação: 2022
Outros Autores: Barile, Katarine Antonia do Santos, Castro, Jairo Augusto Américo de, Palmeira, Maurício Koury, Castro, Renata Bezerra Hermes de, Amaral, Carlos Eduardo de Melo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/27082
Resumo: The present study describes HTLV seroprevalence in potential blood donors from the Brazilian state of Pará, and the sociodemographic characteristics of the infection in this state. This descriptive, retrospective, and cross-sectional study is based on secondary serological and sociodemographic data on potential blood donors who were rejected for presenting reactive results in the serological HTLV screening between January 2010 and December 2020. The mean HTLV seroprevalence was 0.2%. The highest frequency of reactivity was recorded in first-time donors, women, individuals over 30 years old that were single and had a relatively low level of  education. There have been many advances since the discovery of HTLV, although it is still considered to be a neglected etiological agent in Brazil. Further research on data from hematological services will be necessary to refine regional infection profiles, which will be fundamental for the development of adequate prophylactic practises to control and prevent infection, as well the dissemination of information on the dangers of HTLV to the general population.
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spelling Seroprevalence of the Human T Lymphotropic Virus (HTLV 1 and HTLV 2) in Blood Donor Candidates in the State of Pará, Northern Brazil Seroprevalencia del Virus Linfotrópico T Humano (HTLV 1 y HTLV 2) en Candidatos a Donación en el Estado de Pará, Norte de BrasilSoroprevalência do Vírus Linfotrópico T Humano (HTLV 1 e HTLV 2) em Candidatos a Doação no Estado do Pará, Norte do BrasilHTLV infectionBlood donorsSoroprevalência.Infecciones por DeltaretrovirusDonantes de SangreEstudios Seroepidemiológicos.Infecções por HTLVDoadores de sangueSeroprevalence.The present study describes HTLV seroprevalence in potential blood donors from the Brazilian state of Pará, and the sociodemographic characteristics of the infection in this state. This descriptive, retrospective, and cross-sectional study is based on secondary serological and sociodemographic data on potential blood donors who were rejected for presenting reactive results in the serological HTLV screening between January 2010 and December 2020. The mean HTLV seroprevalence was 0.2%. The highest frequency of reactivity was recorded in first-time donors, women, individuals over 30 years old that were single and had a relatively low level of  education. There have been many advances since the discovery of HTLV, although it is still considered to be a neglected etiological agent in Brazil. Further research on data from hematological services will be necessary to refine regional infection profiles, which will be fundamental for the development of adequate prophylactic practises to control and prevent infection, as well the dissemination of information on the dangers of HTLV to the general population.Considerando la significativa seroprevalencia media de infección en donantes de sangre y la transmisión eficiente de HTLV por transfusiones de sangre, los estudios de seroprevalencia de HTLV entre donantes de sangre son de fundamental importancia para revelar la situación específica de la región en relación a este virus, considerando que las regiones brasileñas tienen diferentes condiciones socioeconómicas, demográficas y culturales. Por lo tanto, el objetivo del estudio fue determinar la seroprevalencia de HTLV en donantes de sangre en el Estado de Pará y describir las características epidemiológicas de esta infección. Es un estudio descriptivo, retrospectivo y transversal, basado en datos serológicos y epidemiológicos secundarios de donantes no aptos para la donación de sangre por presentar resultados reactivos en la prueba serológica para HTLV, de enero de 2010 a diciembre de 2020. La seroprevalencia fue de 0,2%. HTLV. La mayor frecuencia de reactividad se encontró entre mujeres, mayores de 30 años, solteras, con menor nivel educativo y donantes primerizas. Es fundamental más investigación en el área de los servicios regionales de hemoterapia y hematología, para contribuir a la definición de perfiles regionales de infección, fundamentales para el desarrollo de prácticas profilácticas en la prevención de la infección, y la difusión del conocimiento sobre los peligros del HTLV en la comunidad.Considerando a significativa soroprevalência média da infecção em doadores de sangue e a eficiente transmissão de HTLV por hemotransfusões, estudos de soroprevalência de HTLV entre doadores de sangue é de fundamental importância para revelar a situação específica da região em relação a este vírus, considerando que as regiões brasileiras apresentam distintas condições socioeconômicas, demográficas e culturais. Portanto o objetivo do estudo foi determinar a soroprevalência do HTLV em doadores de sangue do Estado do Pará, e descrever as características epidemiológicas desta infecção. É um estudo descritivo, retrospectivo e transversal, realizado a partir de dados secundários sorológicos e epidemiológicos de doadores inaptos para a doação de sangue por apresentarem resultados reativos no teste sorológico para HTLV, de janeiro de 2010 a dezembro de 2020. A soroprevalência foi de 0,2% de HTLV. A maior frequência de reatividade foi encontrada entre mulheres, idade superior a 30 anos, solteiros, com menor grau de escolaridade e doadores de primeira. É essencial mais pesquisas na área dos serviços regionais de hemoderapia e hematologia, para contribuir com a definição dos perfis regionais de infecção, fundamentais para o desenvolvimento de práticas profiláticas na prevenção da infecção, e a disseminação do conhecimento sobre os perigos do HTLV na comunidade.Research, Society and Development2022-03-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2708210.33448/rsd-v11i4.27082Research, Society and Development; Vol. 11 No. 4; e1111427082Research, Society and Development; Vol. 11 Núm. 4; e1111427082Research, Society and Development; v. 11 n. 4; e11114270822525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/27082/23615Copyright (c) 2022 Carolina de Alcântara Maneschy; Katarine Antonia do Santos Barile; Jairo Augusto Américo de Castro; Maurício Koury Palmeira; Renata Bezerra Hermes de Castro; Carlos Eduardo de Melo Amaralhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessManeschy, Carolina de AlcântaraBarile, Katarine Antonia do SantosCastro, Jairo Augusto Américo dePalmeira, Maurício KouryCastro, Renata Bezerra Hermes deAmaral, Carlos Eduardo de Melo2022-03-27T17:17:09Zoai:ojs.pkp.sfu.ca:article/27082Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:55.318827Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Seroprevalence of the Human T Lymphotropic Virus (HTLV 1 and HTLV 2) in Blood Donor Candidates in the State of Pará, Northern Brazil
Seroprevalencia del Virus Linfotrópico T Humano (HTLV 1 y HTLV 2) en Candidatos a Donación en el Estado de Pará, Norte de Brasil
Soroprevalência do Vírus Linfotrópico T Humano (HTLV 1 e HTLV 2) em Candidatos a Doação no Estado do Pará, Norte do Brasil
title Seroprevalence of the Human T Lymphotropic Virus (HTLV 1 and HTLV 2) in Blood Donor Candidates in the State of Pará, Northern Brazil
spellingShingle Seroprevalence of the Human T Lymphotropic Virus (HTLV 1 and HTLV 2) in Blood Donor Candidates in the State of Pará, Northern Brazil
Maneschy, Carolina de Alcântara
HTLV infection
Blood donors
Soroprevalência.
Infecciones por Deltaretrovirus
Donantes de Sangre
Estudios Seroepidemiológicos.
Infecções por HTLV
Doadores de sangue
Seroprevalence.
title_short Seroprevalence of the Human T Lymphotropic Virus (HTLV 1 and HTLV 2) in Blood Donor Candidates in the State of Pará, Northern Brazil
title_full Seroprevalence of the Human T Lymphotropic Virus (HTLV 1 and HTLV 2) in Blood Donor Candidates in the State of Pará, Northern Brazil
title_fullStr Seroprevalence of the Human T Lymphotropic Virus (HTLV 1 and HTLV 2) in Blood Donor Candidates in the State of Pará, Northern Brazil
title_full_unstemmed Seroprevalence of the Human T Lymphotropic Virus (HTLV 1 and HTLV 2) in Blood Donor Candidates in the State of Pará, Northern Brazil
title_sort Seroprevalence of the Human T Lymphotropic Virus (HTLV 1 and HTLV 2) in Blood Donor Candidates in the State of Pará, Northern Brazil
author Maneschy, Carolina de Alcântara
author_facet Maneschy, Carolina de Alcântara
Barile, Katarine Antonia do Santos
Castro, Jairo Augusto Américo de
Palmeira, Maurício Koury
Castro, Renata Bezerra Hermes de
Amaral, Carlos Eduardo de Melo
author_role author
author2 Barile, Katarine Antonia do Santos
Castro, Jairo Augusto Américo de
Palmeira, Maurício Koury
Castro, Renata Bezerra Hermes de
Amaral, Carlos Eduardo de Melo
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Maneschy, Carolina de Alcântara
Barile, Katarine Antonia do Santos
Castro, Jairo Augusto Américo de
Palmeira, Maurício Koury
Castro, Renata Bezerra Hermes de
Amaral, Carlos Eduardo de Melo
dc.subject.por.fl_str_mv HTLV infection
Blood donors
Soroprevalência.
Infecciones por Deltaretrovirus
Donantes de Sangre
Estudios Seroepidemiológicos.
Infecções por HTLV
Doadores de sangue
Seroprevalence.
topic HTLV infection
Blood donors
Soroprevalência.
Infecciones por Deltaretrovirus
Donantes de Sangre
Estudios Seroepidemiológicos.
Infecções por HTLV
Doadores de sangue
Seroprevalence.
description The present study describes HTLV seroprevalence in potential blood donors from the Brazilian state of Pará, and the sociodemographic characteristics of the infection in this state. This descriptive, retrospective, and cross-sectional study is based on secondary serological and sociodemographic data on potential blood donors who were rejected for presenting reactive results in the serological HTLV screening between January 2010 and December 2020. The mean HTLV seroprevalence was 0.2%. The highest frequency of reactivity was recorded in first-time donors, women, individuals over 30 years old that were single and had a relatively low level of  education. There have been many advances since the discovery of HTLV, although it is still considered to be a neglected etiological agent in Brazil. Further research on data from hematological services will be necessary to refine regional infection profiles, which will be fundamental for the development of adequate prophylactic practises to control and prevent infection, as well the dissemination of information on the dangers of HTLV to the general population.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-09
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/27082
10.33448/rsd-v11i4.27082
url https://rsdjournal.org/index.php/rsd/article/view/27082
identifier_str_mv 10.33448/rsd-v11i4.27082
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/27082/23615
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 4; e1111427082
Research, Society and Development; Vol. 11 Núm. 4; e1111427082
Research, Society and Development; v. 11 n. 4; e1111427082
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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