The use of Cannabis sativa for the treatment of depression

Detalhes bibliográficos
Autor(a) principal: Silva, Rogeria Rodrigues da
Data de Publicação: 2022
Outros Autores: Almeida, Denner Gomes de, Santos , Jânio Sousa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/35786
Resumo: The objective of the present study was to evidence the use of Cannabis Sativa-based drugs, which aims at its benefits and therapeutic action and to report its mechanism of action in the treatment of Depression. The study was developed from an integrative literature review in which books, dissertations, articles and theses that were published between 2005 and 2021 were searched. Documents published in Portuguese and English that were available in the databases were selected. Scielo, CAPES, PUBMED and LILACS journals. In addition to the databases, official documents from PAHO (Pan American Health Organization) and Ministry of Health were used in the construction of this review. Depression is a disabling disease that affects around 350 million people worldwide. Considering that currently available antidepressants take 2 to 4 weeks to take effect, being ineffective in about 40% of cases, new drugs with rapid antidepressant action, such as that observed by CBD, are of great clinical relevance. It was evidenced about the efficiency of medicines based on Cannabis sativa, which is a medicinal plant with pharmacological properties that present effects as close or similar to neuroleptic medicines, whose active principle used for the manufacture of psychoactive medicines is Cannabidiol (CBD) that helps the central nervous system and the body by reducing and alleviating the effects of depression.
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spelling The use of Cannabis sativa for the treatment of depression El uso de Cannabis sativa para el tratamiento de la depresión A utilização da Cannabis sativa para o tratamento da depressão Maconha medicinalCannabisPrincípio ativoFitoterápicos.Medical marijuanaCannabisActive principleHerbal medicines.Marihuana medicinalCanabisPrincipio activoHierbas medicinales.The objective of the present study was to evidence the use of Cannabis Sativa-based drugs, which aims at its benefits and therapeutic action and to report its mechanism of action in the treatment of Depression. The study was developed from an integrative literature review in which books, dissertations, articles and theses that were published between 2005 and 2021 were searched. Documents published in Portuguese and English that were available in the databases were selected. Scielo, CAPES, PUBMED and LILACS journals. In addition to the databases, official documents from PAHO (Pan American Health Organization) and Ministry of Health were used in the construction of this review. Depression is a disabling disease that affects around 350 million people worldwide. Considering that currently available antidepressants take 2 to 4 weeks to take effect, being ineffective in about 40% of cases, new drugs with rapid antidepressant action, such as that observed by CBD, are of great clinical relevance. It was evidenced about the efficiency of medicines based on Cannabis sativa, which is a medicinal plant with pharmacological properties that present effects as close or similar to neuroleptic medicines, whose active principle used for the manufacture of psychoactive medicines is Cannabidiol (CBD) that helps the central nervous system and the body by reducing and alleviating the effects of depression.El objetivo del presente estudio fue evidenciar el uso de fármacos a base de Cannabis Sativa, buscando sus beneficios y acción terapéutica y relatar su mecanismo de acción en el tratamiento de la Depresión. El estudio se desarrolló a partir de una revisión integrativa de la literatura en la que se buscaron libros, disertaciones, artículos y tesis que hayan sido publicados entre 2005 y 2021. Se seleccionaron documentos publicados en portugués e inglés que estaban disponibles en las bases de datos. Revistas Scielo, CAPES, PUBMED y LILACS. Además de las bases de datos, en la construcción de esta revisión se utilizaron documentos oficiales de la OPS (Organización Panamericana de la Salud) y del Ministerio de Salud. La depresión es una enfermedad incapacitante que afecta a alrededor de 350 millones de personas en todo el mundo. Teniendo en cuenta que los antidepresivos actualmente disponibles tardan de 2 a 4 semanas en hacer efecto, siendo ineficaces en alrededor del 40% de los casos, los nuevos fármacos con acción antidepresiva rápida, como la observada por el CBD, tienen una gran relevancia clínica. Se evidenció sobre la eficacia de medicamentos a base de Cannabis sativa, que es una planta medicinal con propiedades farmacológicas que presenta efectos similares o similares a los medicamentos neurolépticos, cuyo principio activo utilizado para la fabricación de medicamentos psicoactivos es el Cannabidiol (CBD) que ayuda a la sistema nervioso central y el cuerpo al reducir y aliviar los efectos de la depresión.O objetivo do presente estudo foi evidenciar a utilização de medicamentos à base de Cannabis Sativa, que visa seus benefícios e ação terapêutica e relatar o seu mecanismo de ação no tratamento da Depressão. O estudo foi desenvolvido a partir de uma revisão integrativa da literatura na qual foi foram pesquisados livros, dissertações, artigos e teses que foram publicados entre os anos 2005 e 2021. Foram selecionados documentos publicados na língua portuguesa e inglesa que estavam disponíveis nos bancos de dados Scielo, periódicos CAPES, PUBMED e LILACS. Além das bases de dados documentos oficiais da OPAS (Organização Pan – Americana da Saúde) e Ministério da Saúde e foram utilizados na construção da presente revisão. A depressão é uma doença incapacitante que atinge por volta de 350 milhões de pessoas no mundo. Considerando que os antidepressivos disponíveis atualmente demoram de 2 a 4 semanas para produzir efeito, sendo ineficaz em cerca de 40% dos casos, novos medicamentos com ação antidepressiva rápida, como a observada pelo CBD, são de grande relevância clínica. Evidenciou-se sobre a eficiência de medicamentos à base de Cannabis sativa, que é uma planta medicinal de propriedades farmacológicas que apresentam efeitos tão próximos ou semelhantes aos medicamentos neurolépticos, cujo princípio ativo utilizado para a fabricação de medicamentos psicoativos é o Canabidiol (CBD) que ajuda o sistema nervoso central e o organismo reduzindo e amenizando os efeitos da depressão.Research, Society and Development2022-10-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3578610.33448/rsd-v11i14.35786Research, Society and Development; Vol. 11 No. 14; e58111435786Research, Society and Development; Vol. 11 Núm. 14; e58111435786Research, Society and Development; v. 11 n. 14; e581114357862525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/35786/30125Copyright (c) 2022 Rogeria Rodrigues da Silva; Denner Gomes de Almeida; Jânio Sousa Santos https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Rogeria Rodrigues da Almeida, Denner Gomes de Santos , Jânio Sousa 2022-11-08T13:36:27Zoai:ojs.pkp.sfu.ca:article/35786Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:50:34.343230Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv The use of Cannabis sativa for the treatment of depression
El uso de Cannabis sativa para el tratamiento de la depresión
A utilização da Cannabis sativa para o tratamento da depressão
title The use of Cannabis sativa for the treatment of depression
spellingShingle The use of Cannabis sativa for the treatment of depression
Silva, Rogeria Rodrigues da
Maconha medicinal
Cannabis
Princípio ativo
Fitoterápicos.
Medical marijuana
Cannabis
Active principle
Herbal medicines.
Marihuana medicinal
Canabis
Principio activo
Hierbas medicinales.
title_short The use of Cannabis sativa for the treatment of depression
title_full The use of Cannabis sativa for the treatment of depression
title_fullStr The use of Cannabis sativa for the treatment of depression
title_full_unstemmed The use of Cannabis sativa for the treatment of depression
title_sort The use of Cannabis sativa for the treatment of depression
author Silva, Rogeria Rodrigues da
author_facet Silva, Rogeria Rodrigues da
Almeida, Denner Gomes de
Santos , Jânio Sousa
author_role author
author2 Almeida, Denner Gomes de
Santos , Jânio Sousa
author2_role author
author
dc.contributor.author.fl_str_mv Silva, Rogeria Rodrigues da
Almeida, Denner Gomes de
Santos , Jânio Sousa
dc.subject.por.fl_str_mv Maconha medicinal
Cannabis
Princípio ativo
Fitoterápicos.
Medical marijuana
Cannabis
Active principle
Herbal medicines.
Marihuana medicinal
Canabis
Principio activo
Hierbas medicinales.
topic Maconha medicinal
Cannabis
Princípio ativo
Fitoterápicos.
Medical marijuana
Cannabis
Active principle
Herbal medicines.
Marihuana medicinal
Canabis
Principio activo
Hierbas medicinales.
description The objective of the present study was to evidence the use of Cannabis Sativa-based drugs, which aims at its benefits and therapeutic action and to report its mechanism of action in the treatment of Depression. The study was developed from an integrative literature review in which books, dissertations, articles and theses that were published between 2005 and 2021 were searched. Documents published in Portuguese and English that were available in the databases were selected. Scielo, CAPES, PUBMED and LILACS journals. In addition to the databases, official documents from PAHO (Pan American Health Organization) and Ministry of Health were used in the construction of this review. Depression is a disabling disease that affects around 350 million people worldwide. Considering that currently available antidepressants take 2 to 4 weeks to take effect, being ineffective in about 40% of cases, new drugs with rapid antidepressant action, such as that observed by CBD, are of great clinical relevance. It was evidenced about the efficiency of medicines based on Cannabis sativa, which is a medicinal plant with pharmacological properties that present effects as close or similar to neuroleptic medicines, whose active principle used for the manufacture of psychoactive medicines is Cannabidiol (CBD) that helps the central nervous system and the body by reducing and alleviating the effects of depression.
publishDate 2022
dc.date.none.fl_str_mv 2022-10-19
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/35786
10.33448/rsd-v11i14.35786
url https://rsdjournal.org/index.php/rsd/article/view/35786
identifier_str_mv 10.33448/rsd-v11i14.35786
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/35786/30125
dc.rights.driver.fl_str_mv Copyright (c) 2022 Rogeria Rodrigues da Silva; Denner Gomes de Almeida; Jânio Sousa Santos
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Rogeria Rodrigues da Silva; Denner Gomes de Almeida; Jânio Sousa Santos
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 14; e58111435786
Research, Society and Development; Vol. 11 Núm. 14; e58111435786
Research, Society and Development; v. 11 n. 14; e58111435786
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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