Effects of supplementation with polyphenol resveratrol in patients with diabetes mellitus type 2: a systematic review

• Autor(a) principal: Lima, Valéria Silva de
• Data de Publicação: 2020
• Outros Autores: Bezerra, Alane Nogueira, Albuquerque, Natasha Vasconcelos, Pereira , Camila Pinheiro, Alencar, Camila Moreira da Costa, Lima, Ana Thaís Alves, Ferreira, Kelly Christine de Assis
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/8659
• topic: Resveratrol; Diabetes mellitus; Glucose; Oxidative stress.; Resveratrol; Diabetes mellitus; Glucosa; Estrés oxidativo.; Resveratrol; Diabetes mellitus; Glicemia; Estresse oxidativo.

The present study aimed to review the effects of resveratrol supplementation in patients diagnosed with DM2. This is a systematic review, carried out using the electronic databases PubMed, Lilacs and Medline, published in English, from 2011 to 2019, with the descriptors "Resveratrol" and "Diabetes Mellitus". The inclusion criteria used were: randomized clinical trials conducted with individuals with type 2 DM. Studies with animals, pregnant women, lactating women, and individuals under the age of 18 years were excluded. It was observed that the effects of resveratrol supplementation more prevalent in these patients were related to improved insulin sensitivity, glycemic control and a possible reduction in oxidative stress. There are still controversies in the literature regarding its real effectiveness in diabetic patients. However, the use of resveratrol as an adjunct to hypoglycemic therapy is not ruled out.