Evaluation of vitamin D use in patients with asthma: an integrative review

Detalhes bibliográficos
Autor(a) principal: Pinto, Andressa Raiany Henrique
Data de Publicação: 2022
Outros Autores: Santos, Gustavo Pinto dos, Costa, Saulo Prado da, Santos, Pedro Henrique Fernandes Pólvora, Lacerda, Georthon Pereira, Almeida, Natália Caroline Coelho dos Santos, Arruda, Michel Patrik de Sousa, Paz, Beatriz Rodrigues, Oliveira, Mariana de Jesus, Zanoni, Rodrigo Daniel
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/39045
Resumo: Background: Asthma is a chronic inflammatory disease of the airways in which the inflammatory process culminates in recurrent episodes of wheezing, dyspnea, chest tightness and coughing. Recent studies have linked low serum levels of 25-hydroxyvitamin D (vitamin D) to severe asthma exacerbations, decreased lung function, and reduced response to corticosteroids. Objectives: To analyze the effects of the use of vitamin D in patients with asthma, with or without defect in this vitamin. Methods: This is an integrative review, which used PUBMED, SciELO and LILACS databases. Inclusion criteria were: answering the guiding question, being available in Portuguese, English or Spanish, articles published in the last 5 years, of the clinical trial type, reports and case series, cohort studies and cross-sectional studies. After screening, 13 articles were selected. Results and discussion: The results were quite divergent regarding the effectiveness of vitamin D supplementation in asthmatic patients with or without its deficiency, although the majority indicated a strong correlation between vitamin D deficiency and the exacerbation of asthma attacks. Still, factors such as sample type and size and follow-up time can influence the results, showing that there is a more positive correlation in children than in adults. Conclusion: The divergent results in the available literature require that more primary studies be carried out, with a larger and more homogeneous sample, in order to reach more reliable results, which, in fact, support the effectiveness of vitamin D supplementation in these patients.
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spelling Evaluation of vitamin D use in patients with asthma: an integrative reviewEvaluación del uso de vitamina D en pacientes con asma: una revisión integradoraAvaliação do uso de vitamina D em pacientes com asma: uma revisão integrativaAsthmaVitamin DPneumology.AsmaVitamina DNeumología.AsmaVitamina DPneumologia.Background: Asthma is a chronic inflammatory disease of the airways in which the inflammatory process culminates in recurrent episodes of wheezing, dyspnea, chest tightness and coughing. Recent studies have linked low serum levels of 25-hydroxyvitamin D (vitamin D) to severe asthma exacerbations, decreased lung function, and reduced response to corticosteroids. Objectives: To analyze the effects of the use of vitamin D in patients with asthma, with or without defect in this vitamin. Methods: This is an integrative review, which used PUBMED, SciELO and LILACS databases. Inclusion criteria were: answering the guiding question, being available in Portuguese, English or Spanish, articles published in the last 5 years, of the clinical trial type, reports and case series, cohort studies and cross-sectional studies. After screening, 13 articles were selected. Results and discussion: The results were quite divergent regarding the effectiveness of vitamin D supplementation in asthmatic patients with or without its deficiency, although the majority indicated a strong correlation between vitamin D deficiency and the exacerbation of asthma attacks. Still, factors such as sample type and size and follow-up time can influence the results, showing that there is a more positive correlation in children than in adults. Conclusion: The divergent results in the available literature require that more primary studies be carried out, with a larger and more homogeneous sample, in order to reach more reliable results, which, in fact, support the effectiveness of vitamin D supplementation in these patients.Introducción: El asma es una enfermedad inflamatoria crónica de las vías respiratorias en la que el proceso inflamatorio culmina en episodios recurrentes de sibilancias, disnea, opresión torácica y tos. Estudios recientes han relacionado los niveles séricos bajos de 25-hidroxivitamina D (vitamina D) con exacerbaciones graves de asma, función pulmonar disminuida y respuesta reducida a los corticosteroides. Objetivos: Analizar los efectos del uso de vitamina D en pacientes con asma, con o sin defecto de esta vitamina. Métodos: Esta es una revisión integradora, que utilizó las bases de datos PUBMED, SciELO y LILACS. Los criterios de inclusión fueron: responder a la pregunta orientadora, estar disponible en portugués, inglés o español, artículos publicados en los últimos 5 años, del tipo ensayo clínico, informes y series de casos, estudios de cohortes y estudios transversales. Después de la selección, se seleccionaron 13 artículos. Resultados y discusión: Los resultados fueron bastante divergentes con respecto a la efectividad de la suplementación con vitamina D en pacientes asmáticos con o sin su deficiencia, aunque la mayoría indicó una fuerte correlación entre la deficiencia de vitamina D y la exacerbación de los ataques de asma. Aún así, factores como el tipo y tamaño de la muestra y el tiempo de seguimiento pueden influir en los resultados, mostrando que existe una correlación más positiva en niños que en adultos. Conclusión: Los resultados divergentes en la literatura disponible obligan a realizar más estudios primarios, con una muestra mayor y más homogénea, para llegar a resultados más fiables, que, de hecho, avalen la eficacia de la suplementación con vitamina D en estos pacientes.Introdução: A asma é uma doença inflamatória crônica das vias aéreas na qual o processo inflamatório culmina em episódios recorrentes de sibilância, dispneia, aperto no peito e tosse. Estudos recentes tem relacionado os baixos níveis séricos de 25-hidroxivitamina D (vitamina D) a exacerbações graves de asma, diminuição da função pulmonar e resposta reduzida a corticosteroides. Objetivos: Analisar os efeitos do uso da vitamina D em pacientes com asma, com ou sem defeito desta vitamina. Métodos: Trata-se de uma revisão integrativa, que utilizou as bases de dados PUBMED, SciELO e LILACS. Os critérios de inclusão foram: responder à pergunta norteadora, estar disponível em português, inglês ou espanhol, artigos publicados nos últimos 5 anos, do tipo ensaio clínico, relato e séries de casos, estudos de coorte e estudos transversais. Após a triagem, foram selecionados 13 artigos. Resultados e discussão: Os resultados foram bastante divergentes quanto a eficácia da suplementação de vitamina D em pacientes asmáticos com ou sem deficiência desta, embora a maioria tenha indicado uma forte correlação entre a carência vitamínica e a exacerbação das crises de asma. Anda, fatores como o tipo e tamanho de amostra e tempo de seguimento podem influenciar nos resultados, sendo evidenciado que em crianças há uma correlação mais positiva do que em adultos. Conclusão: Os resultados divergentes na literatura disponível requerem que mais estudos primários sejam realizados, com uma amostra maior e mais homogênea, a fim de alcançar resultados mais fidedignos, que embasem, de fato, a eficácia na suplementação de vitamina D nestes pacientes.Research, Society and Development2022-12-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3904510.33448/rsd-v11i17.39045Research, Society and Development; Vol. 11 No. 17; e196111739045Research, Society and Development; Vol. 11 Núm. 17; e196111739045Research, Society and Development; v. 11 n. 17; e1961117390452525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/39045/32212Copyright (c) 2022 Andressa Raiany Henrique Pinto; Gustavo Pinto dos Santos; Saulo Prado da Costa; Pedro Henrique Fernandes Pólvora Santos; Georthon Pereira Lacerda; Natália Caroline Coelho dos Santos Almeida; Michel Patrik de Sousa Arruda; Beatriz Rodrigues Paz; Mariana de Jesus Oliveira; Rodrigo Daniel Zanonihttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPinto, Andressa Raiany Henrique Santos, Gustavo Pinto dos Costa, Saulo Prado da Santos, Pedro Henrique Fernandes Pólvora Lacerda, Georthon Pereira Almeida, Natália Caroline Coelho dos SantosArruda, Michel Patrik de SousaPaz, Beatriz RodriguesOliveira, Mariana de JesusZanoni, Rodrigo Daniel2022-12-28T13:53:48Zoai:ojs.pkp.sfu.ca:article/39045Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:52:28.499184Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Evaluation of vitamin D use in patients with asthma: an integrative review
Evaluación del uso de vitamina D en pacientes con asma: una revisión integradora
Avaliação do uso de vitamina D em pacientes com asma: uma revisão integrativa
title Evaluation of vitamin D use in patients with asthma: an integrative review
spellingShingle Evaluation of vitamin D use in patients with asthma: an integrative review
Pinto, Andressa Raiany Henrique
Asthma
Vitamin D
Pneumology.
Asma
Vitamina D
Neumología.
Asma
Vitamina D
Pneumologia.
title_short Evaluation of vitamin D use in patients with asthma: an integrative review
title_full Evaluation of vitamin D use in patients with asthma: an integrative review
title_fullStr Evaluation of vitamin D use in patients with asthma: an integrative review
title_full_unstemmed Evaluation of vitamin D use in patients with asthma: an integrative review
title_sort Evaluation of vitamin D use in patients with asthma: an integrative review
author Pinto, Andressa Raiany Henrique
author_facet Pinto, Andressa Raiany Henrique
Santos, Gustavo Pinto dos
Costa, Saulo Prado da
Santos, Pedro Henrique Fernandes Pólvora
Lacerda, Georthon Pereira
Almeida, Natália Caroline Coelho dos Santos
Arruda, Michel Patrik de Sousa
Paz, Beatriz Rodrigues
Oliveira, Mariana de Jesus
Zanoni, Rodrigo Daniel
author_role author
author2 Santos, Gustavo Pinto dos
Costa, Saulo Prado da
Santos, Pedro Henrique Fernandes Pólvora
Lacerda, Georthon Pereira
Almeida, Natália Caroline Coelho dos Santos
Arruda, Michel Patrik de Sousa
Paz, Beatriz Rodrigues
Oliveira, Mariana de Jesus
Zanoni, Rodrigo Daniel
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pinto, Andressa Raiany Henrique
Santos, Gustavo Pinto dos
Costa, Saulo Prado da
Santos, Pedro Henrique Fernandes Pólvora
Lacerda, Georthon Pereira
Almeida, Natália Caroline Coelho dos Santos
Arruda, Michel Patrik de Sousa
Paz, Beatriz Rodrigues
Oliveira, Mariana de Jesus
Zanoni, Rodrigo Daniel
dc.subject.por.fl_str_mv Asthma
Vitamin D
Pneumology.
Asma
Vitamina D
Neumología.
Asma
Vitamina D
Pneumologia.
topic Asthma
Vitamin D
Pneumology.
Asma
Vitamina D
Neumología.
Asma
Vitamina D
Pneumologia.
description Background: Asthma is a chronic inflammatory disease of the airways in which the inflammatory process culminates in recurrent episodes of wheezing, dyspnea, chest tightness and coughing. Recent studies have linked low serum levels of 25-hydroxyvitamin D (vitamin D) to severe asthma exacerbations, decreased lung function, and reduced response to corticosteroids. Objectives: To analyze the effects of the use of vitamin D in patients with asthma, with or without defect in this vitamin. Methods: This is an integrative review, which used PUBMED, SciELO and LILACS databases. Inclusion criteria were: answering the guiding question, being available in Portuguese, English or Spanish, articles published in the last 5 years, of the clinical trial type, reports and case series, cohort studies and cross-sectional studies. After screening, 13 articles were selected. Results and discussion: The results were quite divergent regarding the effectiveness of vitamin D supplementation in asthmatic patients with or without its deficiency, although the majority indicated a strong correlation between vitamin D deficiency and the exacerbation of asthma attacks. Still, factors such as sample type and size and follow-up time can influence the results, showing that there is a more positive correlation in children than in adults. Conclusion: The divergent results in the available literature require that more primary studies be carried out, with a larger and more homogeneous sample, in order to reach more reliable results, which, in fact, support the effectiveness of vitamin D supplementation in these patients.
publishDate 2022
dc.date.none.fl_str_mv 2022-12-25
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/39045
10.33448/rsd-v11i17.39045
url https://rsdjournal.org/index.php/rsd/article/view/39045
identifier_str_mv 10.33448/rsd-v11i17.39045
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/39045/32212
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 17; e196111739045
Research, Society and Development; Vol. 11 Núm. 17; e196111739045
Research, Society and Development; v. 11 n. 17; e196111739045
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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