Osteosarcoma of jaw: Diagnosis and treatment challengers
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista da Faculdade de Odontologia de Lins (Online) |
Texto Completo: | https://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/view/4544 |
Resumo: | Introducion: Osteosarcoma is a primary malignant bone tumor most commonly found in long bones. However, in the oral cavity it mainly affects the ramus and angle of the mandible. Objetive: To present a case of osteolytic osteosarcoma of the mandible and discuss the difficulties of diagnosis and treatment. Case Report: A 22-year-old white female patient, non-smoker and non-drinker attended the stomatology service with complaints of increased volume on the right side of the mandible, exhibiting premolar and molar mobility in that area.Periapical and occlusal radiographs were performed and showed presence of radiolucent area and floating teeth, confirmed by a panoramic radiography showing involvement of the mandibular ramus. Two biopsies were performed in the region with inconclusive results for malignancy. The diagnostic hypothesis was osteosarcoma. A CT scan showed bone loss, floating teeth and involvement of areas adjacent to the tumor lesion and lymph nodes. The patient was referred to the oncology hospital and a frozen section biopsy was conclusive for osteosarcoma, with removal of the base and most of the right and left mandible ramus, followed by reconstruction with titanium plate. The tumor recurred and a new surgery, radiotherapy and chemotherapy were performed in an attempt to improve the clinical condition, with failure and death after four years of initial diagnosis and tumor mutation for rhabdomyosarcoma. Conclusion: Imaging and even histopathological outpatient exams were not able to promote the final diagnosis of osteosarcoma, impairing treatment and favoring recurrence and patient death. Key words: Osteosarcoma. Bone tumor. Diagnostic imaging. |
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Osteosarcoma of jaw: Diagnosis and treatment challengersSaúde- Odontologia- Estomatologia- PatologiaOsteosarcoma. Bone tumor. Diagnostic imaging.Introducion: Osteosarcoma is a primary malignant bone tumor most commonly found in long bones. However, in the oral cavity it mainly affects the ramus and angle of the mandible. Objetive: To present a case of osteolytic osteosarcoma of the mandible and discuss the difficulties of diagnosis and treatment. Case Report: A 22-year-old white female patient, non-smoker and non-drinker attended the stomatology service with complaints of increased volume on the right side of the mandible, exhibiting premolar and molar mobility in that area.Periapical and occlusal radiographs were performed and showed presence of radiolucent area and floating teeth, confirmed by a panoramic radiography showing involvement of the mandibular ramus. Two biopsies were performed in the region with inconclusive results for malignancy. The diagnostic hypothesis was osteosarcoma. A CT scan showed bone loss, floating teeth and involvement of areas adjacent to the tumor lesion and lymph nodes. The patient was referred to the oncology hospital and a frozen section biopsy was conclusive for osteosarcoma, with removal of the base and most of the right and left mandible ramus, followed by reconstruction with titanium plate. The tumor recurred and a new surgery, radiotherapy and chemotherapy were performed in an attempt to improve the clinical condition, with failure and death after four years of initial diagnosis and tumor mutation for rhabdomyosarcoma. Conclusion: Imaging and even histopathological outpatient exams were not able to promote the final diagnosis of osteosarcoma, impairing treatment and favoring recurrence and patient death. Key words: Osteosarcoma. Bone tumor. Diagnostic imaging.Universidade Metodista de PiracicabaSem financiamentoAlmeida, Gustavo RodriguesRocha, Bruna Danielli CostaNunes, Nancy Alfieri2020-12-28info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado por paresapplication/pdfhttps://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/view/454410.15600/2238-1236/fol.v30n1p123-132Revista da Faculdade de Odontologia de Lins; v. 30, n. 1-2 (2020): Revista da Faculdade de Odontologia de Lins - Journal of The Lins Dentistry School; 123-1322238-123601047582reponame:Revista da Faculdade de Odontologia de Lins (Online)instname:Universidade Metodista de Piracicaba (UNIMEP)instacron:UNIMEPporhttps://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/view/4544/2514https://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/downloadSuppFile/4544/1484https://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/downloadSuppFile/4544/1485https://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/downloadSuppFile/4544/1486Direitos autorais 2020 Revista da Faculdade de Odontologia de Linsinfo:eu-repo/semantics/openAccess2021-05-20T18:25:18Zoai:ojs-unimep.metodista.br:article/4544Revistahttps://www.metodista.br/revistas/revistas-unimep/index.php/Folhttps://www.metodista.br/revistas/revistas-unimep/index.php/Fol/oai||revistafol@unimep.br|| nalfieri@unimep.br2238-12360104-7582opendoar:2021-05-20T18:25:18Revista da Faculdade de Odontologia de Lins (Online) - Universidade Metodista de Piracicaba (UNIMEP)false |
dc.title.none.fl_str_mv |
Osteosarcoma of jaw: Diagnosis and treatment challengers |
title |
Osteosarcoma of jaw: Diagnosis and treatment challengers |
spellingShingle |
Osteosarcoma of jaw: Diagnosis and treatment challengers Almeida, Gustavo Rodrigues Saúde- Odontologia- Estomatologia- Patologia Osteosarcoma. Bone tumor. Diagnostic imaging. |
title_short |
Osteosarcoma of jaw: Diagnosis and treatment challengers |
title_full |
Osteosarcoma of jaw: Diagnosis and treatment challengers |
title_fullStr |
Osteosarcoma of jaw: Diagnosis and treatment challengers |
title_full_unstemmed |
Osteosarcoma of jaw: Diagnosis and treatment challengers |
title_sort |
Osteosarcoma of jaw: Diagnosis and treatment challengers |
author |
Almeida, Gustavo Rodrigues |
author_facet |
Almeida, Gustavo Rodrigues Rocha, Bruna Danielli Costa Nunes, Nancy Alfieri |
author_role |
author |
author2 |
Rocha, Bruna Danielli Costa Nunes, Nancy Alfieri |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Sem financiamento |
dc.contributor.author.fl_str_mv |
Almeida, Gustavo Rodrigues Rocha, Bruna Danielli Costa Nunes, Nancy Alfieri |
dc.subject.por.fl_str_mv |
Saúde- Odontologia- Estomatologia- Patologia Osteosarcoma. Bone tumor. Diagnostic imaging. |
topic |
Saúde- Odontologia- Estomatologia- Patologia Osteosarcoma. Bone tumor. Diagnostic imaging. |
description |
Introducion: Osteosarcoma is a primary malignant bone tumor most commonly found in long bones. However, in the oral cavity it mainly affects the ramus and angle of the mandible. Objetive: To present a case of osteolytic osteosarcoma of the mandible and discuss the difficulties of diagnosis and treatment. Case Report: A 22-year-old white female patient, non-smoker and non-drinker attended the stomatology service with complaints of increased volume on the right side of the mandible, exhibiting premolar and molar mobility in that area.Periapical and occlusal radiographs were performed and showed presence of radiolucent area and floating teeth, confirmed by a panoramic radiography showing involvement of the mandibular ramus. Two biopsies were performed in the region with inconclusive results for malignancy. The diagnostic hypothesis was osteosarcoma. A CT scan showed bone loss, floating teeth and involvement of areas adjacent to the tumor lesion and lymph nodes. The patient was referred to the oncology hospital and a frozen section biopsy was conclusive for osteosarcoma, with removal of the base and most of the right and left mandible ramus, followed by reconstruction with titanium plate. The tumor recurred and a new surgery, radiotherapy and chemotherapy were performed in an attempt to improve the clinical condition, with failure and death after four years of initial diagnosis and tumor mutation for rhabdomyosarcoma. Conclusion: Imaging and even histopathological outpatient exams were not able to promote the final diagnosis of osteosarcoma, impairing treatment and favoring recurrence and patient death. Key words: Osteosarcoma. Bone tumor. Diagnostic imaging. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-28 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Avaliado por pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/view/4544 10.15600/2238-1236/fol.v30n1p123-132 |
url |
https://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/view/4544 |
identifier_str_mv |
10.15600/2238-1236/fol.v30n1p123-132 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/view/4544/2514 https://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/downloadSuppFile/4544/1484 https://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/downloadSuppFile/4544/1485 https://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/downloadSuppFile/4544/1486 |
dc.rights.driver.fl_str_mv |
Direitos autorais 2020 Revista da Faculdade de Odontologia de Lins info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos autorais 2020 Revista da Faculdade de Odontologia de Lins |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Metodista de Piracicaba |
publisher.none.fl_str_mv |
Universidade Metodista de Piracicaba |
dc.source.none.fl_str_mv |
Revista da Faculdade de Odontologia de Lins; v. 30, n. 1-2 (2020): Revista da Faculdade de Odontologia de Lins - Journal of The Lins Dentistry School; 123-132 2238-1236 01047582 reponame:Revista da Faculdade de Odontologia de Lins (Online) instname:Universidade Metodista de Piracicaba (UNIMEP) instacron:UNIMEP |
instname_str |
Universidade Metodista de Piracicaba (UNIMEP) |
instacron_str |
UNIMEP |
institution |
UNIMEP |
reponame_str |
Revista da Faculdade de Odontologia de Lins (Online) |
collection |
Revista da Faculdade de Odontologia de Lins (Online) |
repository.name.fl_str_mv |
Revista da Faculdade de Odontologia de Lins (Online) - Universidade Metodista de Piracicaba (UNIMEP) |
repository.mail.fl_str_mv |
||revistafol@unimep.br|| nalfieri@unimep.br |
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1754569015663001600 |