Influence of antiretroviral therapy in oral manifestations of patients HIV+/AIDS

• Autor(a) principal: Kreuger, Maria Regina Orofino
• Data de Publicação: 2012
• Outros Autores: Diegoli, Nivaldo Murilo, Pedrini, Rômulo D’Avila, Chaves, Bárbara, Forlin, Daniela de Castro
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista da Faculdade de Odontologia de Lins (Online)
• Texto Completo: https://www.metodista.br/revistas/revistas-unimep/index.php/Fol/article/view/380
• topic: HIV+/AIDS; therapy; complications; oral manifestations.; HIV+/AIDS, terapia; complicações; manifestações bucais.

Human immune deficiency virus (HIV) infection is a pandemic (disease) characterized by severe changes of the imunne system that facilitated the appearance of opportunistic infections and neoplasias,   could leading the patients to the development of the (when patients has developed full blown)  Adquired Immune Deficiency Syndrome (AIDS). Oral manifestations of HIV (HIV+/AIDS) infection are one important factor that indicate the progress of the disease and occur in approximately 80% of infected patients. The aim of this work was to evaluate the influence of antiretroviral therapy in oral manifestations of patients HIV+/AIDS attended at the Hospital Dia - Itajaí (SC). Over one year period, 100 diagnosed HIV/AIDS patients that agreed to participate in this study were examined in a dentistry clinic and interviewed by trained and calibrated examiners, using a structured questionnaire. Clinical history was retrieved from patient's medical records. Results showed that 12 patients were in irregular treatment with anti-retroviral therapy (HAART), 63 in regular treatment and 25 were not receiving HAART. In all the three groups were found oral manifestations, and patients in regular treatment showed lesser cases. Oral candidiasis was the most common oral manifestation and was found in all the three groups. Patients in regular treatment showed CD4 count over than 200 cells/mm, and less viral load.