Aspecos clínico-laboratoriais e epidemiológicos da sífilis congênita em um estado fronteiriço brasileiro e em sua cidade gêmea com maior número de casos

• Autor(a) principal: Kirienco, Mirian Simionato
• Data de Publicação: 2023
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações do UNIOESTE
• Texto Completo: https://tede.unioeste.br/handle/tede/6677
• topic: Sífilis congênita; Áreas de fronteira; Cuidado pré-natal; Saúde pública; Congenital syphilis; Border areas; Prenatal care; Public health; Sífilis congénita; Áreas de frontera; Cuidado prenatal; Salud pública; CIENCIAS DA SAUDE::SAUDE COLETIVA

Congenital syphilis (CS) is an infectious disease, transmitted vertically from untreated infected pregnant women via placenta, resulting from inadequate prenatal care. In this sense, border regions are important sites for investigation of the infection due to the existence of a floating population, which contributes to the increased demand on the Brazilian health service. Objective: To verify the number of cases of CS diagnosed in children up to one year of age in the state of Paraná and its twin cities, focusing on the twin city with the highest number of reported cases in the period from 2011 to 2020, and to investigate the sociodemographic and clinical aspects. Methodology: A descriptive, retrospective-retrospective study with a quantitative approach, developed from secondary data obtained through the Notifiable Diseases Information System. The CS incidence rates were calculated by the constant 1,000. The CS incidence rates of the time series were analyzed with the chi-square trend test. The association between the number of reported CS cases and the investigated variables was analyzed with the χ2 test and the G-test. A p value ≤0.05 was considered and Minitab 18 software was used. Results: 6,088 cases of CS were reported in Paraná, with 338 cases occurring in its twin cities. Foz do Iguaçu was the twin city that presented the highest number of cases (n= 320). The mean annual incidence rate was 3.9 and 7.3 cases/1,000 live births (p<0.05). There was a predominance of pregnant women aged 20 to 29 years 55.6% (p<0.05), low school level 18.4%, skin color, white 73.4%, performed prenatal care 86.3% (p>0.05), diagnosed with syphilis during prenatal care 65.9%, with inadequate treatment 41.3% and no treatment 36.3% (p<0.05). The age range of children with CS was under seven days of life 96.3% (p>0.05). Conclusion: The high incidence of CS in the studied period points to challenges in prenatal care and feasibility of cross-border public policies directed to the reduction and/or eradication of the disease.