A REVIEW ON THE USE OF REMDESIVIR IN THE CURRENT VIROSIS COVID-19.

Detalhes bibliográficos
Autor(a) principal: Andrade de Moura, Ana Maria Marinho
Data de Publicação: 2020
Outros Autores: Andrade de Moura, Anaís Concepción Marinho, kramer, DANY GERALDO
Tipo de documento: Artigo
Idioma: por
Título da fonte: Interfaces Científicas. Saúde e Ambiente (Online)
Texto Completo: https://periodicos.set.edu.br/saude/article/view/8774
Resumo: Remdesivir (GS-5734) is a drug designed for application in patients with Ebola, being used in patients in the coronavirus outbreak in the Middle East. After internalization of the drug, at the cellular level, it is converted into its active form GS-441524, and binds viral RNA polymerase (RdRp) blocking viral replication. Thus, the present study aimed to discuss the potential use of Remdesivir in coronovavirus infections. Some observed studies report promising results in the recovery of critically ill patients with COVID 19, however, there are reports of serious adverse reactions, which led to the discontinuation of therapy with this drug. Thus, measuring the efficacy and safety of Remdesivir in the treatment of COVID 19 will require broader randomized, controlled and double-blind clinical trials, so that the data and scientific information generated can guide treatment protocols for this drug.
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spelling A REVIEW ON THE USE OF REMDESIVIR IN THE CURRENT VIROSIS COVID-19.RemdesivirCoronavirusTherapy.Remdesivir (GS-5734) is a drug designed for application in patients with Ebola, being used in patients in the coronavirus outbreak in the Middle East. After internalization of the drug, at the cellular level, it is converted into its active form GS-441524, and binds viral RNA polymerase (RdRp) blocking viral replication. Thus, the present study aimed to discuss the potential use of Remdesivir in coronovavirus infections. Some observed studies report promising results in the recovery of critically ill patients with COVID 19, however, there are reports of serious adverse reactions, which led to the discontinuation of therapy with this drug. Thus, measuring the efficacy and safety of Remdesivir in the treatment of COVID 19 will require broader randomized, controlled and double-blind clinical trials, so that the data and scientific information generated can guide treatment protocols for this drug.Editora Universitária Tiradentes2020-11-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.set.edu.br/saude/article/view/877410.17564/2316-3798.2020v8n2p272-280Interfaces Científicas - Saúde e Ambiente; v. 8 n. 2 (2020); 272-2802316-37982316-331310.17564/2316-3798.2020v8n2reponame:Interfaces Científicas. Saúde e Ambiente (Online)instname:Universidade Tiradentes (UNIT)instacron:UNITporhttps://periodicos.set.edu.br/saude/article/view/8774/4306Copyright (c) 2020 Interfaces Científicas - Saúde e Ambienteinfo:eu-repo/semantics/openAccessAndrade de Moura, Ana Maria MarinhoAndrade de Moura, Anaís Concepción Marinhokramer, DANY GERALDO2020-11-17T18:17:38Zoai:ojs.emnuvens.com.br:article/8774Revistahttps://periodicos.set.edu.br/saudePRIhttps://periodicos.set.edu.br/index.php/saude/oai||crismporto@gmail.com||interfaces_saude_editor@yahoo.com.br2316-37982316-3313opendoar:2020-11-17T18:17:38Interfaces Científicas. Saúde e Ambiente (Online) - Universidade Tiradentes (UNIT)false
dc.title.none.fl_str_mv A REVIEW ON THE USE OF REMDESIVIR IN THE CURRENT VIROSIS COVID-19.
title A REVIEW ON THE USE OF REMDESIVIR IN THE CURRENT VIROSIS COVID-19.
spellingShingle A REVIEW ON THE USE OF REMDESIVIR IN THE CURRENT VIROSIS COVID-19.
Andrade de Moura, Ana Maria Marinho
Remdesivir
Coronavirus
Therapy.
title_short A REVIEW ON THE USE OF REMDESIVIR IN THE CURRENT VIROSIS COVID-19.
title_full A REVIEW ON THE USE OF REMDESIVIR IN THE CURRENT VIROSIS COVID-19.
title_fullStr A REVIEW ON THE USE OF REMDESIVIR IN THE CURRENT VIROSIS COVID-19.
title_full_unstemmed A REVIEW ON THE USE OF REMDESIVIR IN THE CURRENT VIROSIS COVID-19.
title_sort A REVIEW ON THE USE OF REMDESIVIR IN THE CURRENT VIROSIS COVID-19.
author Andrade de Moura, Ana Maria Marinho
author_facet Andrade de Moura, Ana Maria Marinho
Andrade de Moura, Anaís Concepción Marinho
kramer, DANY GERALDO
author_role author
author2 Andrade de Moura, Anaís Concepción Marinho
kramer, DANY GERALDO
author2_role author
author
dc.contributor.author.fl_str_mv Andrade de Moura, Ana Maria Marinho
Andrade de Moura, Anaís Concepción Marinho
kramer, DANY GERALDO
dc.subject.por.fl_str_mv Remdesivir
Coronavirus
Therapy.
topic Remdesivir
Coronavirus
Therapy.
description Remdesivir (GS-5734) is a drug designed for application in patients with Ebola, being used in patients in the coronavirus outbreak in the Middle East. After internalization of the drug, at the cellular level, it is converted into its active form GS-441524, and binds viral RNA polymerase (RdRp) blocking viral replication. Thus, the present study aimed to discuss the potential use of Remdesivir in coronovavirus infections. Some observed studies report promising results in the recovery of critically ill patients with COVID 19, however, there are reports of serious adverse reactions, which led to the discontinuation of therapy with this drug. Thus, measuring the efficacy and safety of Remdesivir in the treatment of COVID 19 will require broader randomized, controlled and double-blind clinical trials, so that the data and scientific information generated can guide treatment protocols for this drug.
publishDate 2020
dc.date.none.fl_str_mv 2020-11-12
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.set.edu.br/saude/article/view/8774
10.17564/2316-3798.2020v8n2p272-280
url https://periodicos.set.edu.br/saude/article/view/8774
identifier_str_mv 10.17564/2316-3798.2020v8n2p272-280
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.set.edu.br/saude/article/view/8774/4306
dc.rights.driver.fl_str_mv Copyright (c) 2020 Interfaces Científicas - Saúde e Ambiente
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 Interfaces Científicas - Saúde e Ambiente
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Editora Universitária Tiradentes
publisher.none.fl_str_mv Editora Universitária Tiradentes
dc.source.none.fl_str_mv Interfaces Científicas - Saúde e Ambiente; v. 8 n. 2 (2020); 272-280
2316-3798
2316-3313
10.17564/2316-3798.2020v8n2
reponame:Interfaces Científicas. Saúde e Ambiente (Online)
instname:Universidade Tiradentes (UNIT)
instacron:UNIT
instname_str Universidade Tiradentes (UNIT)
instacron_str UNIT
institution UNIT
reponame_str Interfaces Científicas. Saúde e Ambiente (Online)
collection Interfaces Científicas. Saúde e Ambiente (Online)
repository.name.fl_str_mv Interfaces Científicas. Saúde e Ambiente (Online) - Universidade Tiradentes (UNIT)
repository.mail.fl_str_mv ||crismporto@gmail.com||interfaces_saude_editor@yahoo.com.br
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