Impact of combining acerola by-product with a probiotic strain on a gut microbiome model

• Autor(a) principal: Bianchi, Fernanda [UNESP]
• Data de Publicação: 2018
• Outros Autores: Lopes, Natalia Pontin [UNESP], Adorno, Maria Angela Tallarico, Sakamoto, Isabel Kimiko, Genovese, Maria Inés, Saad, Susana Marta Isay, Sivieri, Katia [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1080/09637486.2018.1498065; http://hdl.handle.net/11449/176822
• topic: acerola by-product; human gut microbiota; phenolic compounds; Probiotic; SHIME®

In this study, we first investigated the survival of three probiotic strains, individually and combined with acerola by-product during simulated gastrointestinal conditions. Next, we investigated the effects of acerola by-product combined with Bifidobacterium longum BB-46 on a gut microbiota model (SHIME®). Chemical composition, total phenolic compounds, antioxidant activity of the acerola by-product and microbial counts, denaturing gradient gel electrophoresis (DGGE), ammonium ions (NH+ 4) and short-chain fatty acids (SCFAs) analysis of the SHIME® samples were performed. Acerola by-product revealed high protein and fibre, reduced lipid contents, and showed to be an excellent source of total phenolic compounds with high in vitro antioxidant activity. A decreased amount of NH+ 4 in the ascending colon and an increase (p <.05) in SCFAs were observed in the three regions of colon during treatment with BB-46 and acerola by-product. BB-46 combined with acerola by-product showed positive effects on the gut microbiota metabolism in SHIME® model.