Bone-bioglass graft – An alternative to improve the osseointegration

Detalhes bibliográficos
Autor(a) principal: Lopes, Rauany Cristina
Data de Publicação: 2022
Outros Autores: Furlan, Roberto Gustavo, Correr, Wagner Raphael, Novo, Lísias Pereira, Montrezor, Luís Henrique, Pecoraro, Édison [UNESP], Trovatti, Eliane
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.2298/PAC2203230L
http://hdl.handle.net/11449/249335
Resumo: Homologues and xenogenous bones are currently the most used grafts in dentistry because of their performance. However, some inherent disadvantages of these materials have not yet been overcome, such as the lack of biological properties to improve the new bone formation in situ and the long remodeling time. The main aim of this work was to improve the performance of the commercial bone-based grafts and study its properties in vitro. For this purpose, rat bone was combined with bioglass, a synthetic biomaterial that displays high degradation kinetics and bioactivity properties, endowed with biological properties. The sol-gel method was used for 45S5 bioglass (45S5) synthesis, using TEOS and water soluble salts as starting materials. 45S5 was then associated with the rat bone, generating the new graft. FTIR results indicated the hydroxyapatite formation after the bioactivity tests. SEM and bioactivity results were used to assess the evolution of the graft. The bioactivity tests showed that after 30 days the mass gain of about 30 wt.% was due to the deposition of hydroxyapatite crystals at the surface of the grafts, suggesting the potential properties of this new graft for application in implantology.
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spelling Bone-bioglass graft – An alternative to improve the osseointegrationbioactivitybioglass 45S5bone graftdentistrystructureHomologues and xenogenous bones are currently the most used grafts in dentistry because of their performance. However, some inherent disadvantages of these materials have not yet been overcome, such as the lack of biological properties to improve the new bone formation in situ and the long remodeling time. The main aim of this work was to improve the performance of the commercial bone-based grafts and study its properties in vitro. For this purpose, rat bone was combined with bioglass, a synthetic biomaterial that displays high degradation kinetics and bioactivity properties, endowed with biological properties. The sol-gel method was used for 45S5 bioglass (45S5) synthesis, using TEOS and water soluble salts as starting materials. 45S5 was then associated with the rat bone, generating the new graft. FTIR results indicated the hydroxyapatite formation after the bioactivity tests. SEM and bioactivity results were used to assess the evolution of the graft. The bioactivity tests showed that after 30 days the mass gain of about 30 wt.% was due to the deposition of hydroxyapatite crystals at the surface of the grafts, suggesting the potential properties of this new graft for application in implantology.University of Araraquara - UNIARA, Rua Carlos Gomes, 1217, CEP, SPCentre d’Optique Photonique et Laser. Université Laval, 2375 rue de la TerrasseFederal University of the West of Bahia, R. Teixeira de Freitas, S/n - Assunção Barra - BASão Paulo State University - UNESP Institute of Chemistry, SPSão Paulo State University - UNESP Institute of Chemistry, SPUniversity of Araraquara - UNIARAPhotonique et Laser. Université LavalFederal University of the West of BahiaUniversidade Estadual Paulista (UNESP)Lopes, Rauany CristinaFurlan, Roberto GustavoCorrer, Wagner RaphaelNovo, Lísias PereiraMontrezor, Luís HenriquePecoraro, Édison [UNESP]Trovatti, Eliane2023-07-29T15:13:18Z2023-07-29T15:13:18Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article230-236http://dx.doi.org/10.2298/PAC2203230LProcessing and Application of Ceramics, v. 16, n. 3, p. 230-236, 2022.2406-10341820-6131http://hdl.handle.net/11449/24933510.2298/PAC2203230L2-s2.0-85141313233Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengProcessing and Application of Ceramicsinfo:eu-repo/semantics/openAccess2023-07-29T15:13:19Zoai:repositorio.unesp.br:11449/249335Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:08:27.613199Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Bone-bioglass graft – An alternative to improve the osseointegration
title Bone-bioglass graft – An alternative to improve the osseointegration
spellingShingle Bone-bioglass graft – An alternative to improve the osseointegration
Lopes, Rauany Cristina
bioactivity
bioglass 45S5
bone graft
dentistry
structure
title_short Bone-bioglass graft – An alternative to improve the osseointegration
title_full Bone-bioglass graft – An alternative to improve the osseointegration
title_fullStr Bone-bioglass graft – An alternative to improve the osseointegration
title_full_unstemmed Bone-bioglass graft – An alternative to improve the osseointegration
title_sort Bone-bioglass graft – An alternative to improve the osseointegration
author Lopes, Rauany Cristina
author_facet Lopes, Rauany Cristina
Furlan, Roberto Gustavo
Correr, Wagner Raphael
Novo, Lísias Pereira
Montrezor, Luís Henrique
Pecoraro, Édison [UNESP]
Trovatti, Eliane
author_role author
author2 Furlan, Roberto Gustavo
Correr, Wagner Raphael
Novo, Lísias Pereira
Montrezor, Luís Henrique
Pecoraro, Édison [UNESP]
Trovatti, Eliane
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv University of Araraquara - UNIARA
Photonique et Laser. Université Laval
Federal University of the West of Bahia
Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Lopes, Rauany Cristina
Furlan, Roberto Gustavo
Correr, Wagner Raphael
Novo, Lísias Pereira
Montrezor, Luís Henrique
Pecoraro, Édison [UNESP]
Trovatti, Eliane
dc.subject.por.fl_str_mv bioactivity
bioglass 45S5
bone graft
dentistry
structure
topic bioactivity
bioglass 45S5
bone graft
dentistry
structure
description Homologues and xenogenous bones are currently the most used grafts in dentistry because of their performance. However, some inherent disadvantages of these materials have not yet been overcome, such as the lack of biological properties to improve the new bone formation in situ and the long remodeling time. The main aim of this work was to improve the performance of the commercial bone-based grafts and study its properties in vitro. For this purpose, rat bone was combined with bioglass, a synthetic biomaterial that displays high degradation kinetics and bioactivity properties, endowed with biological properties. The sol-gel method was used for 45S5 bioglass (45S5) synthesis, using TEOS and water soluble salts as starting materials. 45S5 was then associated with the rat bone, generating the new graft. FTIR results indicated the hydroxyapatite formation after the bioactivity tests. SEM and bioactivity results were used to assess the evolution of the graft. The bioactivity tests showed that after 30 days the mass gain of about 30 wt.% was due to the deposition of hydroxyapatite crystals at the surface of the grafts, suggesting the potential properties of this new graft for application in implantology.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
2023-07-29T15:13:18Z
2023-07-29T15:13:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.2298/PAC2203230L
Processing and Application of Ceramics, v. 16, n. 3, p. 230-236, 2022.
2406-1034
1820-6131
http://hdl.handle.net/11449/249335
10.2298/PAC2203230L
2-s2.0-85141313233
url http://dx.doi.org/10.2298/PAC2203230L
http://hdl.handle.net/11449/249335
identifier_str_mv Processing and Application of Ceramics, v. 16, n. 3, p. 230-236, 2022.
2406-1034
1820-6131
10.2298/PAC2203230L
2-s2.0-85141313233
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Processing and Application of Ceramics
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 230-236
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128609889550336