Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios

Detalhes bibliográficos
Autor(a) principal: da Silva Souza, Lorena
Data de Publicação: 2021
Outros Autores: Bonnail, Estefanía, Maranho, Luciane Alves, Pusceddu, Fabio Hermes, Cortez, Fernando Sanzi, Cesar, Augusto, Ribeiro, Daniel Araki, Riba, Inmaculada, de Souza Abessa, Denis M. [UNESP], DelValls, Ángel, Pereira, Camilo Dias Seabra
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/j.marpolbul.2021.112735
http://hdl.handle.net/11449/231479
Resumo: The increasing CO2-concentrations in the atmosphere promote ocean acidification. Seawater chemistry changes interact with contaminants, such as illicit drugs in the coastal zones. This work evaluates impacts of pH decrease and crack-cocaine exposure on the commercial mussel Perna perna through biomarker responses (lysosomal membrane stability, lipid peroxidation, and DNA strand breaks). The organisms were exposed to different crack-cocaine concentrations (0.5, 5.0, and 50 μg L−1) combined with different pH values (8.3, 8.0, 7.5, 7.0, 6.5, and 6.0) for 96 h. Crack-cocaine in the different acidification scenarios triggered cyto-genotoxicity, which affected the overall health of mussels exposed to cocaine environmentally relevant concentration. This study produced the first data on biomarker responses associated with CO2-induced acidification and illicit drugs (crack-cocaine) in marine organisms.
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spelling Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenariosBiomarkersCO2 enrichmentCrack cocaineMarine musselOcean acidificationThe increasing CO2-concentrations in the atmosphere promote ocean acidification. Seawater chemistry changes interact with contaminants, such as illicit drugs in the coastal zones. This work evaluates impacts of pH decrease and crack-cocaine exposure on the commercial mussel Perna perna through biomarker responses (lysosomal membrane stability, lipid peroxidation, and DNA strand breaks). The organisms were exposed to different crack-cocaine concentrations (0.5, 5.0, and 50 μg L−1) combined with different pH values (8.3, 8.0, 7.5, 7.0, 6.5, and 6.0) for 96 h. Crack-cocaine in the different acidification scenarios triggered cyto-genotoxicity, which affected the overall health of mussels exposed to cocaine environmentally relevant concentration. This study produced the first data on biomarker responses associated with CO2-induced acidification and illicit drugs (crack-cocaine) in marine organisms.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Department of Physico-Chemistry Aquatic Systems Research Group UNESCO/UNITWIN WiCop Faculty of Marine and Environmental Sciences University of CádizCentro de Investigaciones Costeras-Universidad de Atacama (CIC-UDA) University of AtacamaDepartment of Ecotoxicology Santa Cecília University (UNISANTA)Department of Marine Sciences Federal University of São Paulo (UNIFESP)Study Center on Pollution and Aquatic Ecotoxicology Paulista State University (UNESP)Study Center on Pollution and Aquatic Ecotoxicology Paulista State University (UNESP)FAPESP: 2018/18456-4CNPq: 409187/2016-0University of CádizUniversity of AtacamaSanta Cecília University (UNISANTA)Universidade de São Paulo (USP)Universidade Estadual Paulista (UNESP)da Silva Souza, LorenaBonnail, EstefaníaMaranho, Luciane AlvesPusceddu, Fabio HermesCortez, Fernando SanziCesar, AugustoRibeiro, Daniel ArakiRiba, Inmaculadade Souza Abessa, Denis M. [UNESP]DelValls, ÁngelPereira, Camilo Dias Seabra2022-04-29T08:45:36Z2022-04-29T08:45:36Z2021-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.marpolbul.2021.112735Marine Pollution Bulletin, v. 171.1879-33630025-326Xhttp://hdl.handle.net/11449/23147910.1016/j.marpolbul.2021.1127352-s2.0-85110693895Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMarine Pollution Bulletininfo:eu-repo/semantics/openAccess2022-04-29T08:45:36Zoai:repositorio.unesp.br:11449/231479Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:24:02.726178Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios
title Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios
spellingShingle Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios
da Silva Souza, Lorena
Biomarkers
CO2 enrichment
Crack cocaine
Marine mussel
Ocean acidification
title_short Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios
title_full Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios
title_fullStr Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios
title_full_unstemmed Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios
title_sort Sub-lethal combined effects of illicit drug and decreased pH on marine mussels: A short-time exposure to crack cocaine in CO2 enrichment scenarios
author da Silva Souza, Lorena
author_facet da Silva Souza, Lorena
Bonnail, Estefanía
Maranho, Luciane Alves
Pusceddu, Fabio Hermes
Cortez, Fernando Sanzi
Cesar, Augusto
Ribeiro, Daniel Araki
Riba, Inmaculada
de Souza Abessa, Denis M. [UNESP]
DelValls, Ángel
Pereira, Camilo Dias Seabra
author_role author
author2 Bonnail, Estefanía
Maranho, Luciane Alves
Pusceddu, Fabio Hermes
Cortez, Fernando Sanzi
Cesar, Augusto
Ribeiro, Daniel Araki
Riba, Inmaculada
de Souza Abessa, Denis M. [UNESP]
DelValls, Ángel
Pereira, Camilo Dias Seabra
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv University of Cádiz
University of Atacama
Santa Cecília University (UNISANTA)
Universidade de São Paulo (USP)
Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv da Silva Souza, Lorena
Bonnail, Estefanía
Maranho, Luciane Alves
Pusceddu, Fabio Hermes
Cortez, Fernando Sanzi
Cesar, Augusto
Ribeiro, Daniel Araki
Riba, Inmaculada
de Souza Abessa, Denis M. [UNESP]
DelValls, Ángel
Pereira, Camilo Dias Seabra
dc.subject.por.fl_str_mv Biomarkers
CO2 enrichment
Crack cocaine
Marine mussel
Ocean acidification
topic Biomarkers
CO2 enrichment
Crack cocaine
Marine mussel
Ocean acidification
description The increasing CO2-concentrations in the atmosphere promote ocean acidification. Seawater chemistry changes interact with contaminants, such as illicit drugs in the coastal zones. This work evaluates impacts of pH decrease and crack-cocaine exposure on the commercial mussel Perna perna through biomarker responses (lysosomal membrane stability, lipid peroxidation, and DNA strand breaks). The organisms were exposed to different crack-cocaine concentrations (0.5, 5.0, and 50 μg L−1) combined with different pH values (8.3, 8.0, 7.5, 7.0, 6.5, and 6.0) for 96 h. Crack-cocaine in the different acidification scenarios triggered cyto-genotoxicity, which affected the overall health of mussels exposed to cocaine environmentally relevant concentration. This study produced the first data on biomarker responses associated with CO2-induced acidification and illicit drugs (crack-cocaine) in marine organisms.
publishDate 2021
dc.date.none.fl_str_mv 2021-10-01
2022-04-29T08:45:36Z
2022-04-29T08:45:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.marpolbul.2021.112735
Marine Pollution Bulletin, v. 171.
1879-3363
0025-326X
http://hdl.handle.net/11449/231479
10.1016/j.marpolbul.2021.112735
2-s2.0-85110693895
url http://dx.doi.org/10.1016/j.marpolbul.2021.112735
http://hdl.handle.net/11449/231479
identifier_str_mv Marine Pollution Bulletin, v. 171.
1879-3363
0025-326X
10.1016/j.marpolbul.2021.112735
2-s2.0-85110693895
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Marine Pollution Bulletin
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129197437091840

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