Ex vivo study of use of physiotherapy ultrasound in polymethylmethacrylate beads doped with methylene blue as an antibiotic carrier
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/1809-6891V22E-68013 http://hdl.handle.net/11449/233459 |
Resumo: | Polymethylmethacrylate bone cement is a standard material used as antibiotic carrier in the orthopedic surgery. The ultrasonic energy method is capable of triggering biological effects based on both thermal and non-thermal mechanisms. The aim of the current study is to analyze methylene blue dispersion in polymethylmethacrylate beads, in association with the acoustic field generated by non-thermal ultrasound. Forty-nine specimens were used, and each specimen comprised one polymethylmethacrylate bead (0.6-mm diameter) doped with methylene blue and deposited in gelatin sample. Forty test specimens were divided into four groups comprising 10 samples, each, based on different ultrasound intensities (Group 1: 1.0 W/cm2; Group 2: 1.5 W/ cm2) and polymethylmethacrylate bead depths (A - 2 cm; B - 3 cm) in gelatin sample. The control group comprised other nine specimens and statistically differed from the other groups. All groups irradiated with ultrasound have shown statistically significant differences in methylene blue dispersion, except for Groups 2A and 2B. Methylene blue dispersion in gelatin among groups was 1A> 1B; 2A> 1A; 2B> 1A; 2A> 1B; and 2B> 1B. Low-intensity ultrasound enabled the highest methylene blue dispersion when polymethylmethacrylate bead was positioned superficial; bead depth associated with high-intensity ultrasound did not influence methylene blue dispersion. |
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Ex vivo study of use of physiotherapy ultrasound in polymethylmethacrylate beads doped with methylene blue as an antibiotic carrierEstudo ex vivo do uso do ultrassom fisioterapêutico em pérolas de polimetilmetacrilato dopadas com azul de metileno como carreador de antibióticoNon-thermal ultrasoundOsteomyelitisPhonophoresisTreatmentPolymethylmethacrylate bone cement is a standard material used as antibiotic carrier in the orthopedic surgery. The ultrasonic energy method is capable of triggering biological effects based on both thermal and non-thermal mechanisms. The aim of the current study is to analyze methylene blue dispersion in polymethylmethacrylate beads, in association with the acoustic field generated by non-thermal ultrasound. Forty-nine specimens were used, and each specimen comprised one polymethylmethacrylate bead (0.6-mm diameter) doped with methylene blue and deposited in gelatin sample. Forty test specimens were divided into four groups comprising 10 samples, each, based on different ultrasound intensities (Group 1: 1.0 W/cm2; Group 2: 1.5 W/ cm2) and polymethylmethacrylate bead depths (A - 2 cm; B - 3 cm) in gelatin sample. The control group comprised other nine specimens and statistically differed from the other groups. All groups irradiated with ultrasound have shown statistically significant differences in methylene blue dispersion, except for Groups 2A and 2B. Methylene blue dispersion in gelatin among groups was 1A> 1B; 2A> 1A; 2B> 1A; 2A> 1B; and 2B> 1B. Low-intensity ultrasound enabled the highest methylene blue dispersion when polymethylmethacrylate bead was positioned superficial; bead depth associated with high-intensity ultrasound did not influence methylene blue dispersion.Universidade Estadual Paulista (UNESP), SPUniversidade de São Paulo (USP), SPUniversidade Estadual Paulista (UNESP), SPUniversidade Estadual Paulista (UNESP)Universidade de São Paulo (USP)Maciel, Luigi Milanez Ávila Dias [UNESP]Rahal, Sheila Canevese [UNESP]Melchert, Alessandra [UNESP]Filho, Tulio Genari [UNESP]Maciel, Carlos DiasDos Santos, Ivan Felismino Charas [UNESP]2022-05-01T08:44:46Z2022-05-01T08:44:46Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1590/1809-6891V22E-68013Ciencia Animal Brasileira, v. 22.1809-68911518-2797http://hdl.handle.net/11449/23345910.1590/1809-6891V22E-680132-s2.0-85113973813Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCiencia Animal Brasileirainfo:eu-repo/semantics/openAccess2022-05-01T08:44:46Zoai:repositorio.unesp.br:11449/233459Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:06:13.632486Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Ex vivo study of use of physiotherapy ultrasound in polymethylmethacrylate beads doped with methylene blue as an antibiotic carrier Estudo ex vivo do uso do ultrassom fisioterapêutico em pérolas de polimetilmetacrilato dopadas com azul de metileno como carreador de antibiótico |
title |
Ex vivo study of use of physiotherapy ultrasound in polymethylmethacrylate beads doped with methylene blue as an antibiotic carrier |
spellingShingle |
Ex vivo study of use of physiotherapy ultrasound in polymethylmethacrylate beads doped with methylene blue as an antibiotic carrier Maciel, Luigi Milanez Ávila Dias [UNESP] Non-thermal ultrasound Osteomyelitis Phonophoresis Treatment |
title_short |
Ex vivo study of use of physiotherapy ultrasound in polymethylmethacrylate beads doped with methylene blue as an antibiotic carrier |
title_full |
Ex vivo study of use of physiotherapy ultrasound in polymethylmethacrylate beads doped with methylene blue as an antibiotic carrier |
title_fullStr |
Ex vivo study of use of physiotherapy ultrasound in polymethylmethacrylate beads doped with methylene blue as an antibiotic carrier |
title_full_unstemmed |
Ex vivo study of use of physiotherapy ultrasound in polymethylmethacrylate beads doped with methylene blue as an antibiotic carrier |
title_sort |
Ex vivo study of use of physiotherapy ultrasound in polymethylmethacrylate beads doped with methylene blue as an antibiotic carrier |
author |
Maciel, Luigi Milanez Ávila Dias [UNESP] |
author_facet |
Maciel, Luigi Milanez Ávila Dias [UNESP] Rahal, Sheila Canevese [UNESP] Melchert, Alessandra [UNESP] Filho, Tulio Genari [UNESP] Maciel, Carlos Dias Dos Santos, Ivan Felismino Charas [UNESP] |
author_role |
author |
author2 |
Rahal, Sheila Canevese [UNESP] Melchert, Alessandra [UNESP] Filho, Tulio Genari [UNESP] Maciel, Carlos Dias Dos Santos, Ivan Felismino Charas [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Maciel, Luigi Milanez Ávila Dias [UNESP] Rahal, Sheila Canevese [UNESP] Melchert, Alessandra [UNESP] Filho, Tulio Genari [UNESP] Maciel, Carlos Dias Dos Santos, Ivan Felismino Charas [UNESP] |
dc.subject.por.fl_str_mv |
Non-thermal ultrasound Osteomyelitis Phonophoresis Treatment |
topic |
Non-thermal ultrasound Osteomyelitis Phonophoresis Treatment |
description |
Polymethylmethacrylate bone cement is a standard material used as antibiotic carrier in the orthopedic surgery. The ultrasonic energy method is capable of triggering biological effects based on both thermal and non-thermal mechanisms. The aim of the current study is to analyze methylene blue dispersion in polymethylmethacrylate beads, in association with the acoustic field generated by non-thermal ultrasound. Forty-nine specimens were used, and each specimen comprised one polymethylmethacrylate bead (0.6-mm diameter) doped with methylene blue and deposited in gelatin sample. Forty test specimens were divided into four groups comprising 10 samples, each, based on different ultrasound intensities (Group 1: 1.0 W/cm2; Group 2: 1.5 W/ cm2) and polymethylmethacrylate bead depths (A - 2 cm; B - 3 cm) in gelatin sample. The control group comprised other nine specimens and statistically differed from the other groups. All groups irradiated with ultrasound have shown statistically significant differences in methylene blue dispersion, except for Groups 2A and 2B. Methylene blue dispersion in gelatin among groups was 1A> 1B; 2A> 1A; 2B> 1A; 2A> 1B; and 2B> 1B. Low-intensity ultrasound enabled the highest methylene blue dispersion when polymethylmethacrylate bead was positioned superficial; bead depth associated with high-intensity ultrasound did not influence methylene blue dispersion. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 2022-05-01T08:44:46Z 2022-05-01T08:44:46Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1809-6891V22E-68013 Ciencia Animal Brasileira, v. 22. 1809-6891 1518-2797 http://hdl.handle.net/11449/233459 10.1590/1809-6891V22E-68013 2-s2.0-85113973813 |
url |
http://dx.doi.org/10.1590/1809-6891V22E-68013 http://hdl.handle.net/11449/233459 |
identifier_str_mv |
Ciencia Animal Brasileira, v. 22. 1809-6891 1518-2797 10.1590/1809-6891V22E-68013 2-s2.0-85113973813 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Ciencia Animal Brasileira |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129284632477696 |