Uterine and luteal hemodynamic evaluation of the non pregnant mare

Detalhes bibliográficos
Autor(a) principal: Ignácio, Fernanda Saules [UNESP]
Data de Publicação: 2011
Outros Autores: Ferreira, Jair Camargo [UNESP], Meira, Cezinande de [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://www.ufrgs.br/actavet/39-suple-1/19%20Supl_s117-s121.pdf
http://hdl.handle.net/11449/73026
Resumo: Background: Studies with Doppler ultrassonography started at the end of the 90s for the determination of physiological and pathological alterations in the reproductive tract of the mare. Uterine alterations caused by inflammation, response from seminal plasma infusion, hormonal variations during estrous and diestrus, pregnancy and action of various vasoactive factors influence on the vascular perfusion detected by Doppler ultrasound. The development of efficient methods for uterine quality evaluation is of big importance for field equine reproduction veterinarians, once uterine environment is responsible for pregnancy maintenance. Review: Nowadays, the most used methods of uterine evaluation are the mode B ultrassonography, cytology, culture and biopsy. Hemodynamic evaluation of the uterus can be done by spectral data collected from large vessels, as A. uterine and its ramifications, or from subjective or objective evaluations from endometrium, miometrium and mesometrium attachment, which provide data referent to local and specific alterations of the evaluated area. Alterations in uterine vascular perfusion has been detected during estrous cycle, during pregnancy and in cases of infusion of inflammatory substances. These alterations happen because of vasoactive substances that act in the uterus during these events, however, most of these vasoactive substances are probably not even known. Also, important hemodynamic alterations in old mares, as an increase in vascular resistance, have been described. This increase might result from fibrosis of the uterus and in women it is considered to be a cause of infertility. In mares, periglandular fibrosis of the endometrium is considered to be the major diagnosable cause of embryonic and fetal loss in older mares. For the CL, ovarian artery of the mare supplies the ovary as well as the oviduct and therefore can be used for evaluation of these areas. The CL evaluation can also be done by the percentage of luteum area with colored signals as an indicator of the extent of blood flow. The percentage of the CL area with colored signals is determined subjectively by images observations in real time and/or by a freezing Power Doppler cross-section image with the maximum number of color pixels taped and the total number of color pixels is assessed by a computer analysis system. Therefore, a high correlation between plasmatic progesterone and CL vascularization also allows the CL evalution by this technique. In a first report, CL circulation reached its maximum on D5, the progesterone concentration in peripheral blood increased until D7 and in a posterior report, maximum perfusion was achieved two days after the maximum progesterone concentration (D8). Blood flow reduced between D10-D14 some days before the plasma progesterone decrease and, during the luteolytic period (D15-D17), the decline in CL blood-flow area was greater than blood flow decrease. Conclusion: Doppler ultrassonography add knowledge about uterine viability and CL functionality can be easily used by veterinarians in the field. It is a noninvasive method that provides real time results. However, because of the short time studies in this area have been done, many other answers still need to be found until normal and pathological patterns will be established.
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spelling Uterine and luteal hemodynamic evaluation of the non pregnant mareCL hemodynamicDoppler ultrassonographyMareReproductionUterine hemodynamicVascular perfusionEquidaeBackground: Studies with Doppler ultrassonography started at the end of the 90s for the determination of physiological and pathological alterations in the reproductive tract of the mare. Uterine alterations caused by inflammation, response from seminal plasma infusion, hormonal variations during estrous and diestrus, pregnancy and action of various vasoactive factors influence on the vascular perfusion detected by Doppler ultrasound. The development of efficient methods for uterine quality evaluation is of big importance for field equine reproduction veterinarians, once uterine environment is responsible for pregnancy maintenance. Review: Nowadays, the most used methods of uterine evaluation are the mode B ultrassonography, cytology, culture and biopsy. Hemodynamic evaluation of the uterus can be done by spectral data collected from large vessels, as A. uterine and its ramifications, or from subjective or objective evaluations from endometrium, miometrium and mesometrium attachment, which provide data referent to local and specific alterations of the evaluated area. Alterations in uterine vascular perfusion has been detected during estrous cycle, during pregnancy and in cases of infusion of inflammatory substances. These alterations happen because of vasoactive substances that act in the uterus during these events, however, most of these vasoactive substances are probably not even known. Also, important hemodynamic alterations in old mares, as an increase in vascular resistance, have been described. This increase might result from fibrosis of the uterus and in women it is considered to be a cause of infertility. In mares, periglandular fibrosis of the endometrium is considered to be the major diagnosable cause of embryonic and fetal loss in older mares. For the CL, ovarian artery of the mare supplies the ovary as well as the oviduct and therefore can be used for evaluation of these areas. The CL evaluation can also be done by the percentage of luteum area with colored signals as an indicator of the extent of blood flow. The percentage of the CL area with colored signals is determined subjectively by images observations in real time and/or by a freezing Power Doppler cross-section image with the maximum number of color pixels taped and the total number of color pixels is assessed by a computer analysis system. Therefore, a high correlation between plasmatic progesterone and CL vascularization also allows the CL evalution by this technique. In a first report, CL circulation reached its maximum on D5, the progesterone concentration in peripheral blood increased until D7 and in a posterior report, maximum perfusion was achieved two days after the maximum progesterone concentration (D8). Blood flow reduced between D10-D14 some days before the plasma progesterone decrease and, during the luteolytic period (D15-D17), the decline in CL blood-flow area was greater than blood flow decrease. Conclusion: Doppler ultrassonography add knowledge about uterine viability and CL functionality can be easily used by veterinarians in the field. It is a noninvasive method that provides real time results. However, because of the short time studies in this area have been done, many other answers still need to be found until normal and pathological patterns will be established.Departamento de Reprodução Animal e Radiologia Veterinária Faculdade de Medicina Veterinária e Zootecnia UNESP, Botucatu, SPDepartamento de Reprodução Animal e Radiologia Veterinária Faculdade de Medicina Veterinária e Zootecnia UNESP, Botucatu, SPUniversidade Estadual Paulista (Unesp)Ignácio, Fernanda Saules [UNESP]Ferreira, Jair Camargo [UNESP]Meira, Cezinande de [UNESP]2014-05-27T11:26:19Z2014-05-27T11:26:19Z2011-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://www.ufrgs.br/actavet/39-suple-1/19%20Supl_s117-s121.pdfActa Scientiae Veterinariae, v. 39, n. SUPPL. 1, 2011.1678-03451679-9216http://hdl.handle.net/11449/730262-s2.0-848686150482-s2.0-84868615048.pdf00429054157111990000-0002-2245-800XScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengActa Scientiae Veterinariae0.2170,1440,144info:eu-repo/semantics/openAccess2024-09-09T14:00:47Zoai:repositorio.unesp.br:11449/73026Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-09T14:00:47Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Uterine and luteal hemodynamic evaluation of the non pregnant mare
title Uterine and luteal hemodynamic evaluation of the non pregnant mare
spellingShingle Uterine and luteal hemodynamic evaluation of the non pregnant mare
Ignácio, Fernanda Saules [UNESP]
CL hemodynamic
Doppler ultrassonography
Mare
Reproduction
Uterine hemodynamic
Vascular perfusion
Equidae
title_short Uterine and luteal hemodynamic evaluation of the non pregnant mare
title_full Uterine and luteal hemodynamic evaluation of the non pregnant mare
title_fullStr Uterine and luteal hemodynamic evaluation of the non pregnant mare
title_full_unstemmed Uterine and luteal hemodynamic evaluation of the non pregnant mare
title_sort Uterine and luteal hemodynamic evaluation of the non pregnant mare
author Ignácio, Fernanda Saules [UNESP]
author_facet Ignácio, Fernanda Saules [UNESP]
Ferreira, Jair Camargo [UNESP]
Meira, Cezinande de [UNESP]
author_role author
author2 Ferreira, Jair Camargo [UNESP]
Meira, Cezinande de [UNESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Ignácio, Fernanda Saules [UNESP]
Ferreira, Jair Camargo [UNESP]
Meira, Cezinande de [UNESP]
dc.subject.por.fl_str_mv CL hemodynamic
Doppler ultrassonography
Mare
Reproduction
Uterine hemodynamic
Vascular perfusion
Equidae
topic CL hemodynamic
Doppler ultrassonography
Mare
Reproduction
Uterine hemodynamic
Vascular perfusion
Equidae
description Background: Studies with Doppler ultrassonography started at the end of the 90s for the determination of physiological and pathological alterations in the reproductive tract of the mare. Uterine alterations caused by inflammation, response from seminal plasma infusion, hormonal variations during estrous and diestrus, pregnancy and action of various vasoactive factors influence on the vascular perfusion detected by Doppler ultrasound. The development of efficient methods for uterine quality evaluation is of big importance for field equine reproduction veterinarians, once uterine environment is responsible for pregnancy maintenance. Review: Nowadays, the most used methods of uterine evaluation are the mode B ultrassonography, cytology, culture and biopsy. Hemodynamic evaluation of the uterus can be done by spectral data collected from large vessels, as A. uterine and its ramifications, or from subjective or objective evaluations from endometrium, miometrium and mesometrium attachment, which provide data referent to local and specific alterations of the evaluated area. Alterations in uterine vascular perfusion has been detected during estrous cycle, during pregnancy and in cases of infusion of inflammatory substances. These alterations happen because of vasoactive substances that act in the uterus during these events, however, most of these vasoactive substances are probably not even known. Also, important hemodynamic alterations in old mares, as an increase in vascular resistance, have been described. This increase might result from fibrosis of the uterus and in women it is considered to be a cause of infertility. In mares, periglandular fibrosis of the endometrium is considered to be the major diagnosable cause of embryonic and fetal loss in older mares. For the CL, ovarian artery of the mare supplies the ovary as well as the oviduct and therefore can be used for evaluation of these areas. The CL evaluation can also be done by the percentage of luteum area with colored signals as an indicator of the extent of blood flow. The percentage of the CL area with colored signals is determined subjectively by images observations in real time and/or by a freezing Power Doppler cross-section image with the maximum number of color pixels taped and the total number of color pixels is assessed by a computer analysis system. Therefore, a high correlation between plasmatic progesterone and CL vascularization also allows the CL evalution by this technique. In a first report, CL circulation reached its maximum on D5, the progesterone concentration in peripheral blood increased until D7 and in a posterior report, maximum perfusion was achieved two days after the maximum progesterone concentration (D8). Blood flow reduced between D10-D14 some days before the plasma progesterone decrease and, during the luteolytic period (D15-D17), the decline in CL blood-flow area was greater than blood flow decrease. Conclusion: Doppler ultrassonography add knowledge about uterine viability and CL functionality can be easily used by veterinarians in the field. It is a noninvasive method that provides real time results. However, because of the short time studies in this area have been done, many other answers still need to be found until normal and pathological patterns will be established.
publishDate 2011
dc.date.none.fl_str_mv 2011-12-01
2014-05-27T11:26:19Z
2014-05-27T11:26:19Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.ufrgs.br/actavet/39-suple-1/19%20Supl_s117-s121.pdf
Acta Scientiae Veterinariae, v. 39, n. SUPPL. 1, 2011.
1678-0345
1679-9216
http://hdl.handle.net/11449/73026
2-s2.0-84868615048
2-s2.0-84868615048.pdf
0042905415711199
0000-0002-2245-800X
url http://www.ufrgs.br/actavet/39-suple-1/19%20Supl_s117-s121.pdf
http://hdl.handle.net/11449/73026
identifier_str_mv Acta Scientiae Veterinariae, v. 39, n. SUPPL. 1, 2011.
1678-0345
1679-9216
2-s2.0-84868615048
2-s2.0-84868615048.pdf
0042905415711199
0000-0002-2245-800X
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Acta Scientiae Veterinariae
0.217
0,144
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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