Lipase-oxovanadium heterogeneous catalysis system: a robust protocol for the dynamic kinetic resolution of sec-alcohols
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1002/cctc.202000292 http://hdl.handle.net/11449/198696 |
Resumo: | Herein, we present a robust and eco-friendly dynamic kinetic resolution (DKR) protocol for secondary alcohols using a combined heterogeneous catalytic CAL−B/VOSO4 system at 50 °C in the relatively green solvent heptane. This catalytic system is active and chemo- and enantioselective for up to 5 cycles. A set of 13 aromatic and heteroaromatic secondary alcohols were evaluated to determine the substrate scope. The performance of the combined CAL−B/VOSO4 system was improved by employing a low-cost, homemade Teflon tube to compartmentalize the catalysts in one-pot conditions, making this system for up to 8 reaction cycles. |
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Repositório Institucional da UNESP |
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2946 |
spelling |
Lipase-oxovanadium heterogeneous catalysis system: a robust protocol for the dynamic kinetic resolution of sec-alcoholsdynamic kinetic resolutionheterogeneous catalysislipasesec-alcoholsvanadiumHerein, we present a robust and eco-friendly dynamic kinetic resolution (DKR) protocol for secondary alcohols using a combined heterogeneous catalytic CAL−B/VOSO4 system at 50 °C in the relatively green solvent heptane. This catalytic system is active and chemo- and enantioselective for up to 5 cycles. A set of 13 aromatic and heteroaromatic secondary alcohols were evaluated to determine the substrate scope. The performance of the combined CAL−B/VOSO4 system was improved by employing a low-cost, homemade Teflon tube to compartmentalize the catalysts in one-pot conditions, making this system for up to 8 reaction cycles.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Institute of Chemistry São Paulo State University (Unesp), Prof. Francisco Degni, 55 – QuitandinhaInstitute of Chemistry São Paulo State University (Unesp), Prof. Francisco Degni, 55 – QuitandinhaFAPESP: 2014/50249-8Universidade Estadual Paulista (Unesp)De Almeida, Laiza A. [UNESP]Marcondes, Thayna H. [UNESP]Milagre, Cintia D. F. [UNESP]Milagre, Humberto M. S. [UNESP]2020-12-12T01:19:41Z2020-12-12T01:19:41Z2020-05-20info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2849-2858http://dx.doi.org/10.1002/cctc.202000292ChemCatChem, v. 12, n. 10, p. 2849-2858, 2020.1867-38991867-3880http://hdl.handle.net/11449/19869610.1002/cctc.2020002922-s2.0-85082757875Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengChemCatCheminfo:eu-repo/semantics/openAccess2021-10-22T19:32:50Zoai:repositorio.unesp.br:11449/198696Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T15:05:59.930750Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Lipase-oxovanadium heterogeneous catalysis system: a robust protocol for the dynamic kinetic resolution of sec-alcohols |
title |
Lipase-oxovanadium heterogeneous catalysis system: a robust protocol for the dynamic kinetic resolution of sec-alcohols |
spellingShingle |
Lipase-oxovanadium heterogeneous catalysis system: a robust protocol for the dynamic kinetic resolution of sec-alcohols De Almeida, Laiza A. [UNESP] dynamic kinetic resolution heterogeneous catalysis lipase sec-alcohols vanadium |
title_short |
Lipase-oxovanadium heterogeneous catalysis system: a robust protocol for the dynamic kinetic resolution of sec-alcohols |
title_full |
Lipase-oxovanadium heterogeneous catalysis system: a robust protocol for the dynamic kinetic resolution of sec-alcohols |
title_fullStr |
Lipase-oxovanadium heterogeneous catalysis system: a robust protocol for the dynamic kinetic resolution of sec-alcohols |
title_full_unstemmed |
Lipase-oxovanadium heterogeneous catalysis system: a robust protocol for the dynamic kinetic resolution of sec-alcohols |
title_sort |
Lipase-oxovanadium heterogeneous catalysis system: a robust protocol for the dynamic kinetic resolution of sec-alcohols |
author |
De Almeida, Laiza A. [UNESP] |
author_facet |
De Almeida, Laiza A. [UNESP] Marcondes, Thayna H. [UNESP] Milagre, Cintia D. F. [UNESP] Milagre, Humberto M. S. [UNESP] |
author_role |
author |
author2 |
Marcondes, Thayna H. [UNESP] Milagre, Cintia D. F. [UNESP] Milagre, Humberto M. S. [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
De Almeida, Laiza A. [UNESP] Marcondes, Thayna H. [UNESP] Milagre, Cintia D. F. [UNESP] Milagre, Humberto M. S. [UNESP] |
dc.subject.por.fl_str_mv |
dynamic kinetic resolution heterogeneous catalysis lipase sec-alcohols vanadium |
topic |
dynamic kinetic resolution heterogeneous catalysis lipase sec-alcohols vanadium |
description |
Herein, we present a robust and eco-friendly dynamic kinetic resolution (DKR) protocol for secondary alcohols using a combined heterogeneous catalytic CAL−B/VOSO4 system at 50 °C in the relatively green solvent heptane. This catalytic system is active and chemo- and enantioselective for up to 5 cycles. A set of 13 aromatic and heteroaromatic secondary alcohols were evaluated to determine the substrate scope. The performance of the combined CAL−B/VOSO4 system was improved by employing a low-cost, homemade Teflon tube to compartmentalize the catalysts in one-pot conditions, making this system for up to 8 reaction cycles. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T01:19:41Z 2020-12-12T01:19:41Z 2020-05-20 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1002/cctc.202000292 ChemCatChem, v. 12, n. 10, p. 2849-2858, 2020. 1867-3899 1867-3880 http://hdl.handle.net/11449/198696 10.1002/cctc.202000292 2-s2.0-85082757875 |
url |
http://dx.doi.org/10.1002/cctc.202000292 http://hdl.handle.net/11449/198696 |
identifier_str_mv |
ChemCatChem, v. 12, n. 10, p. 2849-2858, 2020. 1867-3899 1867-3880 10.1002/cctc.202000292 2-s2.0-85082757875 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
ChemCatChem |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
2849-2858 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128461380780032 |