Nutritional parameters are associated with mortality in acute kidney injury
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.6061/clinics/2014(07)06 http://hdl.handle.net/11449/117634 |
Resumo: | OBJECTIVE: The objective of this study was to perform a nutritional assessment of acute kidney injury patients and to identify the relationship between nutritional markers and outcomes.METHOD: This was a prospective and observational study. Patients who were hospitalized at the Hospital of Botucatu School of Medicine were evaluated between January 2009 and December 2011. We evaluated a total of 133 patients with a clinical diagnosis of acute kidney injury and a clinical presentation suggestive of acute tubular necrosis. We explored the associations between clinical, laboratory and nutritional markers and in hospital mortality. Multivariable logistic regression was used to adjust for confounding and selection bias.RESULTS: Non-survivor patients were older (67 +/- 14 vs. 59 +/- 16 years) and exhibited a higher prevalence of sepsis (57.1 vs. 21.4%) and higher Acute Tubular Necrosis-Individual Severity Scores (0.60 +/- 0.22 vs. 0.41 +/- 0.21) than did survivor patients. Based on the multivariable analysis, laboratorial parameters such as blood urea nitrogen and C-reactive protein were associated with a higher risk of death (OR: 1.013, p = 0.0052; OR: 1.050, p = 0.01, respectively), and nutritional parameters such as low calorie intake, higher levels of edema, lower resistance based on bioelectrical impedance analysis and a more negative nitrogen balance were significantly associated with a higher risk of death (OR: 0.950, p = 0.01; OR: 1.138, p = 0.03; OR: 0.995, p = 0.03; OR: 0.934, p = 0.04, respectively).CONCLUSIONS: In acute kidney injury patients, a nutritional assessment seems to identify nutritional markers that are associated with outcome. In this study, a low caloric intake, higher C-reactive protein levels, the presence of edema, a lower resistance measured during a bioelectrical impedance analysis and a lower nitrogen balance were significantly associated with risk of death in acute kidney injury patients. |
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Nutritional parameters are associated with mortality in acute kidney injuryAcute Kidney InjuryAnthropometryNitrogen BalanceNutritionNutrition AssessmentOBJECTIVE: The objective of this study was to perform a nutritional assessment of acute kidney injury patients and to identify the relationship between nutritional markers and outcomes.METHOD: This was a prospective and observational study. Patients who were hospitalized at the Hospital of Botucatu School of Medicine were evaluated between January 2009 and December 2011. We evaluated a total of 133 patients with a clinical diagnosis of acute kidney injury and a clinical presentation suggestive of acute tubular necrosis. We explored the associations between clinical, laboratory and nutritional markers and in hospital mortality. Multivariable logistic regression was used to adjust for confounding and selection bias.RESULTS: Non-survivor patients were older (67 +/- 14 vs. 59 +/- 16 years) and exhibited a higher prevalence of sepsis (57.1 vs. 21.4%) and higher Acute Tubular Necrosis-Individual Severity Scores (0.60 +/- 0.22 vs. 0.41 +/- 0.21) than did survivor patients. Based on the multivariable analysis, laboratorial parameters such as blood urea nitrogen and C-reactive protein were associated with a higher risk of death (OR: 1.013, p = 0.0052; OR: 1.050, p = 0.01, respectively), and nutritional parameters such as low calorie intake, higher levels of edema, lower resistance based on bioelectrical impedance analysis and a more negative nitrogen balance were significantly associated with a higher risk of death (OR: 0.950, p = 0.01; OR: 1.138, p = 0.03; OR: 0.995, p = 0.03; OR: 0.934, p = 0.04, respectively).CONCLUSIONS: In acute kidney injury patients, a nutritional assessment seems to identify nutritional markers that are associated with outcome. In this study, a low caloric intake, higher C-reactive protein levels, the presence of edema, a lower resistance measured during a bioelectrical impedance analysis and a lower nitrogen balance were significantly associated with risk of death in acute kidney injury patients.UNESP, Botucatu Sch Med, Botucatu, SP, BrazilUNESP, Botucatu Sch Med, Botucatu, SP, BrazilHospital Clinicas, Univ Sao PauloUniversidade Estadual Paulista (Unesp)Berbel, Marina Nogueira [UNESP]Goes, Cassiana Regina de [UNESP]Balbi, André Luis [UNESP]Ponce, Daniela [UNESP]2015-03-18T15:56:35Z2015-03-18T15:56:35Z2014-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article476-482application/pdfhttp://dx.doi.org/10.6061/clinics/2014(07)06Clinics. Sao Paulo: Hospital Clinicas, Univ Sao Paulo, v. 69, n. 7, p. 476-482, 2014.1807-5932http://hdl.handle.net/11449/11763410.6061/clinics/2014(07)06WOS:000341379400006WOS000341379400006.pdf5697804493071661Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengClinics1.2450,536info:eu-repo/semantics/openAccess2024-08-14T17:23:33Zoai:repositorio.unesp.br:11449/117634Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-14T17:23:33Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Nutritional parameters are associated with mortality in acute kidney injury |
title |
Nutritional parameters are associated with mortality in acute kidney injury |
spellingShingle |
Nutritional parameters are associated with mortality in acute kidney injury Berbel, Marina Nogueira [UNESP] Acute Kidney Injury Anthropometry Nitrogen Balance Nutrition Nutrition Assessment |
title_short |
Nutritional parameters are associated with mortality in acute kidney injury |
title_full |
Nutritional parameters are associated with mortality in acute kidney injury |
title_fullStr |
Nutritional parameters are associated with mortality in acute kidney injury |
title_full_unstemmed |
Nutritional parameters are associated with mortality in acute kidney injury |
title_sort |
Nutritional parameters are associated with mortality in acute kidney injury |
author |
Berbel, Marina Nogueira [UNESP] |
author_facet |
Berbel, Marina Nogueira [UNESP] Goes, Cassiana Regina de [UNESP] Balbi, André Luis [UNESP] Ponce, Daniela [UNESP] |
author_role |
author |
author2 |
Goes, Cassiana Regina de [UNESP] Balbi, André Luis [UNESP] Ponce, Daniela [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Berbel, Marina Nogueira [UNESP] Goes, Cassiana Regina de [UNESP] Balbi, André Luis [UNESP] Ponce, Daniela [UNESP] |
dc.subject.por.fl_str_mv |
Acute Kidney Injury Anthropometry Nitrogen Balance Nutrition Nutrition Assessment |
topic |
Acute Kidney Injury Anthropometry Nitrogen Balance Nutrition Nutrition Assessment |
description |
OBJECTIVE: The objective of this study was to perform a nutritional assessment of acute kidney injury patients and to identify the relationship between nutritional markers and outcomes.METHOD: This was a prospective and observational study. Patients who were hospitalized at the Hospital of Botucatu School of Medicine were evaluated between January 2009 and December 2011. We evaluated a total of 133 patients with a clinical diagnosis of acute kidney injury and a clinical presentation suggestive of acute tubular necrosis. We explored the associations between clinical, laboratory and nutritional markers and in hospital mortality. Multivariable logistic regression was used to adjust for confounding and selection bias.RESULTS: Non-survivor patients were older (67 +/- 14 vs. 59 +/- 16 years) and exhibited a higher prevalence of sepsis (57.1 vs. 21.4%) and higher Acute Tubular Necrosis-Individual Severity Scores (0.60 +/- 0.22 vs. 0.41 +/- 0.21) than did survivor patients. Based on the multivariable analysis, laboratorial parameters such as blood urea nitrogen and C-reactive protein were associated with a higher risk of death (OR: 1.013, p = 0.0052; OR: 1.050, p = 0.01, respectively), and nutritional parameters such as low calorie intake, higher levels of edema, lower resistance based on bioelectrical impedance analysis and a more negative nitrogen balance were significantly associated with a higher risk of death (OR: 0.950, p = 0.01; OR: 1.138, p = 0.03; OR: 0.995, p = 0.03; OR: 0.934, p = 0.04, respectively).CONCLUSIONS: In acute kidney injury patients, a nutritional assessment seems to identify nutritional markers that are associated with outcome. In this study, a low caloric intake, higher C-reactive protein levels, the presence of edema, a lower resistance measured during a bioelectrical impedance analysis and a lower nitrogen balance were significantly associated with risk of death in acute kidney injury patients. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-01-01 2015-03-18T15:56:35Z 2015-03-18T15:56:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.6061/clinics/2014(07)06 Clinics. Sao Paulo: Hospital Clinicas, Univ Sao Paulo, v. 69, n. 7, p. 476-482, 2014. 1807-5932 http://hdl.handle.net/11449/117634 10.6061/clinics/2014(07)06 WOS:000341379400006 WOS000341379400006.pdf 5697804493071661 |
url |
http://dx.doi.org/10.6061/clinics/2014(07)06 http://hdl.handle.net/11449/117634 |
identifier_str_mv |
Clinics. Sao Paulo: Hospital Clinicas, Univ Sao Paulo, v. 69, n. 7, p. 476-482, 2014. 1807-5932 10.6061/clinics/2014(07)06 WOS:000341379400006 WOS000341379400006.pdf 5697804493071661 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Clinics 1.245 0,536 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
476-482 application/pdf |
dc.publisher.none.fl_str_mv |
Hospital Clinicas, Univ Sao Paulo |
publisher.none.fl_str_mv |
Hospital Clinicas, Univ Sao Paulo |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128170486923264 |