Microbiological assay for cefoxitin sodium in dosage form

Detalhes bibliográficos
Autor(a) principal: Salgado, Hérida Regina Nunes [UNESP]
Data de Publicação: 2007
Outros Autores: Tozo, Greici Cristiani Gomes [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1093/jaoac/90.2.452
http://hdl.handle.net/11449/231812
Resumo: A microbiological assay applying the cylinder-plate method is described for determination of the activity of cefoxitin sodium in injectables. Using a strain of Staphylococcus epidermidis ATCC 12226 as the test organism, cefoxitin sodium was measured in concentrations ranging from 50.0 to 200.0 μg/mL. The validation showed that the method was linear (r = 0.9998), precise (RSD = 0.81%), and accurate. It was concluded that the microbiological assay is satisfactory for quantitation of cefoxitin sodium in injectables.
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spelling Microbiological assay for cefoxitin sodium in dosage formA microbiological assay applying the cylinder-plate method is described for determination of the activity of cefoxitin sodium in injectables. Using a strain of Staphylococcus epidermidis ATCC 12226 as the test organism, cefoxitin sodium was measured in concentrations ranging from 50.0 to 200.0 μg/mL. The validation showed that the method was linear (r = 0.9998), precise (RSD = 0.81%), and accurate. It was concluded that the microbiological assay is satisfactory for quantitation of cefoxitin sodium in injectables.Faculdade de Ciências Farmacêuticas Programa de Pós-graduação em Ciências Farmacêuticas UNESP, Rod. Araraquara-Jaú, km 1, CEP 14801-902, Araraquara, SPFaculdade de Ciências Farmacêuticas Programa de Pós-graduação em Ciências Farmacêuticas UNESP, Rod. Araraquara-Jaú, km 1, CEP 14801-902, Araraquara, SPUniversidade Estadual Paulista (UNESP)Salgado, Hérida Regina Nunes [UNESP]Tozo, Greici Cristiani Gomes [UNESP]2022-04-29T08:47:41Z2022-04-29T08:47:41Z2007-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article452-455http://dx.doi.org/10.1093/jaoac/90.2.452Journal of AOAC International, v. 90, n. 2, p. 452-455, 2007.1060-3271http://hdl.handle.net/11449/23181210.1093/jaoac/90.2.4522-s2.0-34447643250Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of AOAC Internationalinfo:eu-repo/semantics/openAccess2024-06-24T13:46:33Zoai:repositorio.unesp.br:11449/231812Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:37:06.949220Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Microbiological assay for cefoxitin sodium in dosage form
title Microbiological assay for cefoxitin sodium in dosage form
spellingShingle Microbiological assay for cefoxitin sodium in dosage form
Salgado, Hérida Regina Nunes [UNESP]
title_short Microbiological assay for cefoxitin sodium in dosage form
title_full Microbiological assay for cefoxitin sodium in dosage form
title_fullStr Microbiological assay for cefoxitin sodium in dosage form
title_full_unstemmed Microbiological assay for cefoxitin sodium in dosage form
title_sort Microbiological assay for cefoxitin sodium in dosage form
author Salgado, Hérida Regina Nunes [UNESP]
author_facet Salgado, Hérida Regina Nunes [UNESP]
Tozo, Greici Cristiani Gomes [UNESP]
author_role author
author2 Tozo, Greici Cristiani Gomes [UNESP]
author2_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Salgado, Hérida Regina Nunes [UNESP]
Tozo, Greici Cristiani Gomes [UNESP]
description A microbiological assay applying the cylinder-plate method is described for determination of the activity of cefoxitin sodium in injectables. Using a strain of Staphylococcus epidermidis ATCC 12226 as the test organism, cefoxitin sodium was measured in concentrations ranging from 50.0 to 200.0 μg/mL. The validation showed that the method was linear (r = 0.9998), precise (RSD = 0.81%), and accurate. It was concluded that the microbiological assay is satisfactory for quantitation of cefoxitin sodium in injectables.
publishDate 2007
dc.date.none.fl_str_mv 2007-01-01
2022-04-29T08:47:41Z
2022-04-29T08:47:41Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1093/jaoac/90.2.452
Journal of AOAC International, v. 90, n. 2, p. 452-455, 2007.
1060-3271
http://hdl.handle.net/11449/231812
10.1093/jaoac/90.2.452
2-s2.0-34447643250
url http://dx.doi.org/10.1093/jaoac/90.2.452
http://hdl.handle.net/11449/231812
identifier_str_mv Journal of AOAC International, v. 90, n. 2, p. 452-455, 2007.
1060-3271
10.1093/jaoac/90.2.452
2-s2.0-34447643250
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of AOAC International
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 452-455
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129536941883392

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