Association between different levels of dysglycemia and metabolic syndrome in pregnancy
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1186/1758-5996-1-3 http://hdl.handle.net/11449/12251 |
Resumo: | Background: In this study, we sought to evaluate the prevalence of metabolic syndrome (MS) in a cohort of pregnant women with a wide range of glucose tolerance, prepregnancy risk factors for MS during pregnancy, and the effects of MS in the outcomes in the mother and in the newborn.Methods: One hundred and thirty six women with positive screening for gestational diabetes mellitus (GDM) were classified by two diagnostic methods: glycemic profile and 100 g OGTT as normoglycemic, mild gestational hyperglycemic, GDM, and overt GDM. Markers of MS were measured between 2428(th) during the screening.Results: The prevalence of MS was: 0%; 20.0%; 23.5% and 36.4% in normoglycemic, mild hyperglycemic, GDM, and overt GDM groups, respectively. Previous history of GDM with or without insulin use, BMI >= 25, hypertension, family history of diabetes in first degree relatives, non-Caucasian ethnicity, history of prematurity and polihydramnios were statistically significant prepregnancy predictors for MS in the index pregnancy, that by its turn increased the adverse outcomes in the mother and in the newborn.Conclusion: The prevalence of MS increases with the worsening of glucose tolerance; impaired glycemic profile identifies pregnancies with important metabolic abnormalities even in the presence of a normal OGTT, in patients that are not classified as having GDM. |
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Repositório Institucional da UNESP |
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spelling |
Association between different levels of dysglycemia and metabolic syndrome in pregnancyBackground: In this study, we sought to evaluate the prevalence of metabolic syndrome (MS) in a cohort of pregnant women with a wide range of glucose tolerance, prepregnancy risk factors for MS during pregnancy, and the effects of MS in the outcomes in the mother and in the newborn.Methods: One hundred and thirty six women with positive screening for gestational diabetes mellitus (GDM) were classified by two diagnostic methods: glycemic profile and 100 g OGTT as normoglycemic, mild gestational hyperglycemic, GDM, and overt GDM. Markers of MS were measured between 2428(th) during the screening.Results: The prevalence of MS was: 0%; 20.0%; 23.5% and 36.4% in normoglycemic, mild hyperglycemic, GDM, and overt GDM groups, respectively. Previous history of GDM with or without insulin use, BMI >= 25, hypertension, family history of diabetes in first degree relatives, non-Caucasian ethnicity, history of prematurity and polihydramnios were statistically significant prepregnancy predictors for MS in the index pregnancy, that by its turn increased the adverse outcomes in the mother and in the newborn.Conclusion: The prevalence of MS increases with the worsening of glucose tolerance; impaired glycemic profile identifies pregnancies with important metabolic abnormalities even in the presence of a normal OGTT, in patients that are not classified as having GDM.São Paulo State Univ UNESP, Sch Med Botucatu, São Paulo, BrazilSansum Diabet Res Inst, Santa Barbara, CA USASão Paulo State Univ UNESP, Sch Sci, São Paulo, BrazilState Univ Campinas UNICAMP, Sch Med Sci, São Paulo, BrazilSão Paulo State Univ UNESP, Sch Med Botucatu, São Paulo, BrazilSão Paulo State Univ UNESP, Sch Sci, São Paulo, BrazilBiomed Central Ltd.Sansum Diabet Res InstUniversidade Estadual Paulista (Unesp)Universidade Estadual de Campinas (UNICAMP)Negrato, Carlos A. [UNESP]Jovanovic, LoisRafacho, Alex [UNESP]Tambascia, Marcos A.Geloneze, BrunoDias, Adriano [UNESP]Rudge, Marilza Vieira Cunha [UNESP]2014-05-20T13:35:34Z2014-05-20T13:35:34Z2009-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article6application/pdfhttp://dx.doi.org/10.1186/1758-5996-1-3Diabetology & Metabolic Syndrome. London: Biomed Central Ltd., v. 1, p. 6, 2009.1758-5996http://hdl.handle.net/11449/1225110.1186/1758-5996-1-3WOS:000207918200003WOS000207918200003.pdf675868038883507829668464060628360000-0002-9227-832XWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengDiabetology & Metabolic Syndrome2.4130,943info:eu-repo/semantics/openAccess2023-12-27T06:17:56Zoai:repositorio.unesp.br:11449/12251Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-12-27T06:17:56Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Association between different levels of dysglycemia and metabolic syndrome in pregnancy |
title |
Association between different levels of dysglycemia and metabolic syndrome in pregnancy |
spellingShingle |
Association between different levels of dysglycemia and metabolic syndrome in pregnancy Negrato, Carlos A. [UNESP] |
title_short |
Association between different levels of dysglycemia and metabolic syndrome in pregnancy |
title_full |
Association between different levels of dysglycemia and metabolic syndrome in pregnancy |
title_fullStr |
Association between different levels of dysglycemia and metabolic syndrome in pregnancy |
title_full_unstemmed |
Association between different levels of dysglycemia and metabolic syndrome in pregnancy |
title_sort |
Association between different levels of dysglycemia and metabolic syndrome in pregnancy |
author |
Negrato, Carlos A. [UNESP] |
author_facet |
Negrato, Carlos A. [UNESP] Jovanovic, Lois Rafacho, Alex [UNESP] Tambascia, Marcos A. Geloneze, Bruno Dias, Adriano [UNESP] Rudge, Marilza Vieira Cunha [UNESP] |
author_role |
author |
author2 |
Jovanovic, Lois Rafacho, Alex [UNESP] Tambascia, Marcos A. Geloneze, Bruno Dias, Adriano [UNESP] Rudge, Marilza Vieira Cunha [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Sansum Diabet Res Inst Universidade Estadual Paulista (Unesp) Universidade Estadual de Campinas (UNICAMP) |
dc.contributor.author.fl_str_mv |
Negrato, Carlos A. [UNESP] Jovanovic, Lois Rafacho, Alex [UNESP] Tambascia, Marcos A. Geloneze, Bruno Dias, Adriano [UNESP] Rudge, Marilza Vieira Cunha [UNESP] |
description |
Background: In this study, we sought to evaluate the prevalence of metabolic syndrome (MS) in a cohort of pregnant women with a wide range of glucose tolerance, prepregnancy risk factors for MS during pregnancy, and the effects of MS in the outcomes in the mother and in the newborn.Methods: One hundred and thirty six women with positive screening for gestational diabetes mellitus (GDM) were classified by two diagnostic methods: glycemic profile and 100 g OGTT as normoglycemic, mild gestational hyperglycemic, GDM, and overt GDM. Markers of MS were measured between 2428(th) during the screening.Results: The prevalence of MS was: 0%; 20.0%; 23.5% and 36.4% in normoglycemic, mild hyperglycemic, GDM, and overt GDM groups, respectively. Previous history of GDM with or without insulin use, BMI >= 25, hypertension, family history of diabetes in first degree relatives, non-Caucasian ethnicity, history of prematurity and polihydramnios were statistically significant prepregnancy predictors for MS in the index pregnancy, that by its turn increased the adverse outcomes in the mother and in the newborn.Conclusion: The prevalence of MS increases with the worsening of glucose tolerance; impaired glycemic profile identifies pregnancies with important metabolic abnormalities even in the presence of a normal OGTT, in patients that are not classified as having GDM. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-01-01 2014-05-20T13:35:34Z 2014-05-20T13:35:34Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1186/1758-5996-1-3 Diabetology & Metabolic Syndrome. London: Biomed Central Ltd., v. 1, p. 6, 2009. 1758-5996 http://hdl.handle.net/11449/12251 10.1186/1758-5996-1-3 WOS:000207918200003 WOS000207918200003.pdf 6758680388835078 2966846406062836 0000-0002-9227-832X |
url |
http://dx.doi.org/10.1186/1758-5996-1-3 http://hdl.handle.net/11449/12251 |
identifier_str_mv |
Diabetology & Metabolic Syndrome. London: Biomed Central Ltd., v. 1, p. 6, 2009. 1758-5996 10.1186/1758-5996-1-3 WOS:000207918200003 WOS000207918200003.pdf 6758680388835078 2966846406062836 0000-0002-9227-832X |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Diabetology & Metabolic Syndrome 2.413 0,943 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
6 application/pdf |
dc.publisher.none.fl_str_mv |
Biomed Central Ltd. |
publisher.none.fl_str_mv |
Biomed Central Ltd. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965420717867008 |