Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatment
Main Author: | |
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Publication Date: | 2014 |
Other Authors: | , , , , , , |
Format: | Article |
Language: | eng |
Source: | Repositório Institucional da UNESP |
Download full: | http://hdl.handle.net/11449/220174 |
Summary: | Bisphosphonates are a type of drugs known to inhibit bone resorption through complex interventions. Their primary mechanism of action is aimed at the cellular level, inhibiting osteoclast activity and, thus, bone resorption. Bisphosphonates are, therefore, very widely used, with many patients receiving continuous treatment for years. But it is well known that these drugs can produce osteonecrosis of the jaw and this is their principal risk. A 75-year-old woman received dental treatment before starting intravenous BP therapy for a breast cancer. She started intravenous bisphosphonate treatment with monthly protocol and after two years the patient presented a wound compatible with osteonecrosis of the jaw. |
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Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatmentBisphosphonatesChlorhexidineOsteonecrosis of the jawBisphosphonates are a type of drugs known to inhibit bone resorption through complex interventions. Their primary mechanism of action is aimed at the cellular level, inhibiting osteoclast activity and, thus, bone resorption. Bisphosphonates are, therefore, very widely used, with many patients receiving continuous treatment for years. But it is well known that these drugs can produce osteonecrosis of the jaw and this is their principal risk. A 75-year-old woman received dental treatment before starting intravenous BP therapy for a breast cancer. She started intravenous bisphosphonate treatment with monthly protocol and after two years the patient presented a wound compatible with osteonecrosis of the jaw.Pharmacological Research in Dentistry Group, Faculty of Dentistry, University of Granada, GranadeExtremadura Health Service, Cáceres Health Center Area SESFaculty of Odontology of Araçatuba, University of the State of São PauloFaculty of Medicine and Dentistry, University of MurciaPharmacological Research in Dentistry Group, Faculty of Dentistry, University of GranadaExtremadura Health Service, Cáceres Health Center Area SESFaculty of Odontology of Araçatuba, University of the State of São PauloFaculty of Medicine and Dentistry, University of MurciaGómez-Moreno, G.Arribas-Fernández, M. C.Fernández-Guerrero, M.Boquete-Castro, A.Aguilar-Salvatierra, A.Guardia, J.Botticelli, D.Calvo-Guirado, J. L.2022-04-28T18:59:58Z2022-04-28T18:59:58Z2014-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1391-1397European Review for Medical and Pharmacological Sciences, v. 18, n. 9, p. 1391-1397, 2014.1128-3602http://hdl.handle.net/11449/2201742-s2.0-84902136491Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengEuropean Review for Medical and Pharmacological Sciencesinfo:eu-repo/semantics/openAccess2022-04-28T18:59:58Zoai:repositorio.unesp.br:11449/220174Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T18:59:58Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatment |
title |
Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatment |
spellingShingle |
Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatment Gómez-Moreno, G. Bisphosphonates Chlorhexidine Osteonecrosis of the jaw |
title_short |
Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatment |
title_full |
Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatment |
title_fullStr |
Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatment |
title_full_unstemmed |
Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatment |
title_sort |
Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatment |
author |
Gómez-Moreno, G. |
author_facet |
Gómez-Moreno, G. Arribas-Fernández, M. C. Fernández-Guerrero, M. Boquete-Castro, A. Aguilar-Salvatierra, A. Guardia, J. Botticelli, D. Calvo-Guirado, J. L. |
author_role |
author |
author2 |
Arribas-Fernández, M. C. Fernández-Guerrero, M. Boquete-Castro, A. Aguilar-Salvatierra, A. Guardia, J. Botticelli, D. Calvo-Guirado, J. L. |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Pharmacological Research in Dentistry Group, Faculty of Dentistry, University of Granada Extremadura Health Service, Cáceres Health Center Area SES Faculty of Odontology of Araçatuba, University of the State of São Paulo Faculty of Medicine and Dentistry, University of Murcia |
dc.contributor.author.fl_str_mv |
Gómez-Moreno, G. Arribas-Fernández, M. C. Fernández-Guerrero, M. Boquete-Castro, A. Aguilar-Salvatierra, A. Guardia, J. Botticelli, D. Calvo-Guirado, J. L. |
dc.subject.por.fl_str_mv |
Bisphosphonates Chlorhexidine Osteonecrosis of the jaw |
topic |
Bisphosphonates Chlorhexidine Osteonecrosis of the jaw |
description |
Bisphosphonates are a type of drugs known to inhibit bone resorption through complex interventions. Their primary mechanism of action is aimed at the cellular level, inhibiting osteoclast activity and, thus, bone resorption. Bisphosphonates are, therefore, very widely used, with many patients receiving continuous treatment for years. But it is well known that these drugs can produce osteonecrosis of the jaw and this is their principal risk. A 75-year-old woman received dental treatment before starting intravenous BP therapy for a breast cancer. She started intravenous bisphosphonate treatment with monthly protocol and after two years the patient presented a wound compatible with osteonecrosis of the jaw. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-01-01 2022-04-28T18:59:58Z 2022-04-28T18:59:58Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
European Review for Medical and Pharmacological Sciences, v. 18, n. 9, p. 1391-1397, 2014. 1128-3602 http://hdl.handle.net/11449/220174 2-s2.0-84902136491 |
identifier_str_mv |
European Review for Medical and Pharmacological Sciences, v. 18, n. 9, p. 1391-1397, 2014. 1128-3602 2-s2.0-84902136491 |
url |
http://hdl.handle.net/11449/220174 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
European Review for Medical and Pharmacological Sciences |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1391-1397 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1797789688755388416 |