Enteric nervous system analyses: New biomarkers for environmental quality assessment
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.marpolbul.2018.11.015 http://hdl.handle.net/11449/189673 |
Resumo: | The gastrointestinal tract (GIT) of fish is a target of contaminants since it can absorb these substances. We evaluated the morphophysiological alterations in the GIT of Sphoeroides testudineus collected in two estuaries presenting differences in their environmental quality (NIA and IA). The intestine was analyzed for histological and neuronal changes; liver and gills for biochemical markers; muscle tissues for neurotoxicity and peripheral blood for genotoxic damage. The results showed alterations in the GIT of the animals collected in the IA, such as muscle tunica and goblet cell density reduction, increased intraepithelial lymphocytes density and changes in neuronal density. Furthermore, changes were observed in MTs and LPO in the gills. Thus, we suggest that TGI is functioning as a barrier that responds to ingested contaminants, in order to reduce their absorption and translocation. Thus, alterations in morphophysiological and enteric neurons in S. testudineus can be used as biomarkers of environmental contamination. |
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Enteric nervous system analyses: New biomarkers for environmental quality assessmentAcetylcholinesteraseAquatic pollutionFishMyenteric plexusNitric oxideThe gastrointestinal tract (GIT) of fish is a target of contaminants since it can absorb these substances. We evaluated the morphophysiological alterations in the GIT of Sphoeroides testudineus collected in two estuaries presenting differences in their environmental quality (NIA and IA). The intestine was analyzed for histological and neuronal changes; liver and gills for biochemical markers; muscle tissues for neurotoxicity and peripheral blood for genotoxic damage. The results showed alterations in the GIT of the animals collected in the IA, such as muscle tunica and goblet cell density reduction, increased intraepithelial lymphocytes density and changes in neuronal density. Furthermore, changes were observed in MTs and LPO in the gills. Thus, we suggest that TGI is functioning as a barrier that responds to ingested contaminants, in order to reduce their absorption and translocation. Thus, alterations in morphophysiological and enteric neurons in S. testudineus can be used as biomarkers of environmental contamination.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)São Paulo State University (UNESP) Institute of Biosciences, Praça Infante Dom Henrique, s/n, Parque BitaruDepartment of Marine Sciences Federal University of São Paulo, Santos Campus (UNIFESP — Santos), Av. Almirante Saldanha da Gama, 89Genetics Department Federal University of Paraná (UFPR)São Paulo State University (UNESP) Institute of Biosciences, Praça Infante Dom Henrique, s/n, Parque BitaruFAPESP: 2014/07793-9Universidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Universidade Federal do Paraná (UFPR)Pustiglione Marinsek, Gabriela [UNESP]Moledo de Souza Abessa, Denis [UNESP]Gusso-Choueri, Paloma Kachel [UNESP]Brasil Choueri, RodrigoNascimento Gonçalves, Alexandre Rodrigo [UNESP]D'angelo Barroso, Beatriz Vivian [UNESP]Souza Santos, GustavoMargarete Cestari, MartaGalvão de Campos, Bruno [UNESP]de Britto Mari, Renata [UNESP]2019-10-06T16:48:25Z2019-10-06T16:48:25Z2018-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article711-722http://dx.doi.org/10.1016/j.marpolbul.2018.11.015Marine Pollution Bulletin, v. 137, p. 711-722.1879-33630025-326Xhttp://hdl.handle.net/11449/18967310.1016/j.marpolbul.2018.11.0152-s2.0-85056635267Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMarine Pollution Bulletininfo:eu-repo/semantics/openAccess2021-10-23T19:23:37Zoai:repositorio.unesp.br:11449/189673Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T19:23:37Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Enteric nervous system analyses: New biomarkers for environmental quality assessment |
title |
Enteric nervous system analyses: New biomarkers for environmental quality assessment |
spellingShingle |
Enteric nervous system analyses: New biomarkers for environmental quality assessment Pustiglione Marinsek, Gabriela [UNESP] Acetylcholinesterase Aquatic pollution Fish Myenteric plexus Nitric oxide |
title_short |
Enteric nervous system analyses: New biomarkers for environmental quality assessment |
title_full |
Enteric nervous system analyses: New biomarkers for environmental quality assessment |
title_fullStr |
Enteric nervous system analyses: New biomarkers for environmental quality assessment |
title_full_unstemmed |
Enteric nervous system analyses: New biomarkers for environmental quality assessment |
title_sort |
Enteric nervous system analyses: New biomarkers for environmental quality assessment |
author |
Pustiglione Marinsek, Gabriela [UNESP] |
author_facet |
Pustiglione Marinsek, Gabriela [UNESP] Moledo de Souza Abessa, Denis [UNESP] Gusso-Choueri, Paloma Kachel [UNESP] Brasil Choueri, Rodrigo Nascimento Gonçalves, Alexandre Rodrigo [UNESP] D'angelo Barroso, Beatriz Vivian [UNESP] Souza Santos, Gustavo Margarete Cestari, Marta Galvão de Campos, Bruno [UNESP] de Britto Mari, Renata [UNESP] |
author_role |
author |
author2 |
Moledo de Souza Abessa, Denis [UNESP] Gusso-Choueri, Paloma Kachel [UNESP] Brasil Choueri, Rodrigo Nascimento Gonçalves, Alexandre Rodrigo [UNESP] D'angelo Barroso, Beatriz Vivian [UNESP] Souza Santos, Gustavo Margarete Cestari, Marta Galvão de Campos, Bruno [UNESP] de Britto Mari, Renata [UNESP] |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) Universidade Federal do Paraná (UFPR) |
dc.contributor.author.fl_str_mv |
Pustiglione Marinsek, Gabriela [UNESP] Moledo de Souza Abessa, Denis [UNESP] Gusso-Choueri, Paloma Kachel [UNESP] Brasil Choueri, Rodrigo Nascimento Gonçalves, Alexandre Rodrigo [UNESP] D'angelo Barroso, Beatriz Vivian [UNESP] Souza Santos, Gustavo Margarete Cestari, Marta Galvão de Campos, Bruno [UNESP] de Britto Mari, Renata [UNESP] |
dc.subject.por.fl_str_mv |
Acetylcholinesterase Aquatic pollution Fish Myenteric plexus Nitric oxide |
topic |
Acetylcholinesterase Aquatic pollution Fish Myenteric plexus Nitric oxide |
description |
The gastrointestinal tract (GIT) of fish is a target of contaminants since it can absorb these substances. We evaluated the morphophysiological alterations in the GIT of Sphoeroides testudineus collected in two estuaries presenting differences in their environmental quality (NIA and IA). The intestine was analyzed for histological and neuronal changes; liver and gills for biochemical markers; muscle tissues for neurotoxicity and peripheral blood for genotoxic damage. The results showed alterations in the GIT of the animals collected in the IA, such as muscle tunica and goblet cell density reduction, increased intraepithelial lymphocytes density and changes in neuronal density. Furthermore, changes were observed in MTs and LPO in the gills. Thus, we suggest that TGI is functioning as a barrier that responds to ingested contaminants, in order to reduce their absorption and translocation. Thus, alterations in morphophysiological and enteric neurons in S. testudineus can be used as biomarkers of environmental contamination. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-01 2019-10-06T16:48:25Z 2019-10-06T16:48:25Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.marpolbul.2018.11.015 Marine Pollution Bulletin, v. 137, p. 711-722. 1879-3363 0025-326X http://hdl.handle.net/11449/189673 10.1016/j.marpolbul.2018.11.015 2-s2.0-85056635267 |
url |
http://dx.doi.org/10.1016/j.marpolbul.2018.11.015 http://hdl.handle.net/11449/189673 |
identifier_str_mv |
Marine Pollution Bulletin, v. 137, p. 711-722. 1879-3363 0025-326X 10.1016/j.marpolbul.2018.11.015 2-s2.0-85056635267 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Marine Pollution Bulletin |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
711-722 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965737841852416 |