Reduced Fat Oxidation During Exercise in Post-Menopausal Overweight-Obese Women with Higher Lipid Accumulation Product Index
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1055/a-0801-8730 http://hdl.handle.net/11449/199225 |
Resumo: | BACKGROUND AND AIMS: The main aim of this study was to analyze how the lipid accumulation affects the whole-body fat oxidation over a range of intensities during a submaximal incremental exercise test in post-menopausal overweight-obese women. PATIENTS AND METHODS: The maximal fat oxidation (MFO), the intensity where the MFO occurs (FatMax), fat oxidation were measured over a range of intensities during a submaximal incremental exercise test through indirect calorimetry in 60 postmenopausal overweight-obese women (aged>49 years; body mass index 28.0 to 39.0 kg/m²). The metabolic profile of participants was evaluated and the LAP index was calculated (waist-58×triglycerides [mmol/L]). A cutoff point of 34.5 was adopted and participant were designed as low LAP index (n=30) or high LAP index (n=30). RESULTS: During submaximal exercise postmenopausal overweight-obese women with low LAP index showed a higher fat oxidation at 50% (0.53±0.05 vs. 0.45±0.12 g/min; p=0.01), 60% (0.40±0.06 vs. 0.31±0.16 g/min; p=0.02) and 70% (0.34±0.08 vs. 0.25±0.15 g/min; p=0.03) of VO2Peak than those with high LAP index. No significant difference was observed in carbohydrate oxidation between groups (p>0.05) during exercise. Moreover, a significant difference in absolute MFO (p=0.018), MFO relative to free fat mass (p=0.043) and FatMax (p=0.002) was identified. CONCLUSION: Postmenopausal overweight-obese women who showed unhealthy metabolic phenotype evaluated through LAP index presented low fat oxidation during a submaximal incremental exercise. |
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Reduced Fat Oxidation During Exercise in Post-Menopausal Overweight-Obese Women with Higher Lipid Accumulation Product IndexBACKGROUND AND AIMS: The main aim of this study was to analyze how the lipid accumulation affects the whole-body fat oxidation over a range of intensities during a submaximal incremental exercise test in post-menopausal overweight-obese women. PATIENTS AND METHODS: The maximal fat oxidation (MFO), the intensity where the MFO occurs (FatMax), fat oxidation were measured over a range of intensities during a submaximal incremental exercise test through indirect calorimetry in 60 postmenopausal overweight-obese women (aged>49 years; body mass index 28.0 to 39.0 kg/m²). The metabolic profile of participants was evaluated and the LAP index was calculated (waist-58×triglycerides [mmol/L]). A cutoff point of 34.5 was adopted and participant were designed as low LAP index (n=30) or high LAP index (n=30). RESULTS: During submaximal exercise postmenopausal overweight-obese women with low LAP index showed a higher fat oxidation at 50% (0.53±0.05 vs. 0.45±0.12 g/min; p=0.01), 60% (0.40±0.06 vs. 0.31±0.16 g/min; p=0.02) and 70% (0.34±0.08 vs. 0.25±0.15 g/min; p=0.03) of VO2Peak than those with high LAP index. No significant difference was observed in carbohydrate oxidation between groups (p>0.05) during exercise. Moreover, a significant difference in absolute MFO (p=0.018), MFO relative to free fat mass (p=0.043) and FatMax (p=0.002) was identified. CONCLUSION: Postmenopausal overweight-obese women who showed unhealthy metabolic phenotype evaluated through LAP index presented low fat oxidation during a submaximal incremental exercise.Graduate Program in Nutrition Sciences Laboratory of Cellular and Molecular Immunology Federal University of Health Sciences of Porto Alegre Porto Alegre RSGraduate Program in Health Sciences Laboratory of Cellular and Molecular Immunology Federal University of Health Sciences of Porto Alegre RSExercise and Immunometabolism Research Group Post-Graduation Program in Movement Sciences Department of Physical Education State University of São Paulo - UNESP. School of Technology and SciencesGraduate Program in Rehabilitation Sciences Laboratory of Cellular and Molecular Immunology Federal University of Health Sciences of Porto Alegre RSResearch Center Graduate Program in Bioscience and Rehabilitation Methodist University Center IPA RSExercise and Immunometabolism Research Group Post-Graduation Program in Movement Sciences Department of Physical Education State University of São Paulo - UNESP. School of Technology and SciencesRSUniversidade Estadual Paulista (Unesp)Stein, ElanaSilva, Igor MartinsDorneles, Gilson P.Lira, Fabio Santos [UNESP]Romão, PedroPeres, Alessandra2020-12-12T01:34:08Z2020-12-12T01:34:08Z2020-08-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article556-562http://dx.doi.org/10.1055/a-0801-8730Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, v. 128, n. 8, p. 556-562, 2020.1439-3646http://hdl.handle.net/11449/19922510.1055/a-0801-87302-s2.0-85089127946Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengExperimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Associationinfo:eu-repo/semantics/openAccess2021-10-23T05:02:03Zoai:repositorio.unesp.br:11449/199225Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:59:05.012771Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Reduced Fat Oxidation During Exercise in Post-Menopausal Overweight-Obese Women with Higher Lipid Accumulation Product Index |
title |
Reduced Fat Oxidation During Exercise in Post-Menopausal Overweight-Obese Women with Higher Lipid Accumulation Product Index |
spellingShingle |
Reduced Fat Oxidation During Exercise in Post-Menopausal Overweight-Obese Women with Higher Lipid Accumulation Product Index Stein, Elana |
title_short |
Reduced Fat Oxidation During Exercise in Post-Menopausal Overweight-Obese Women with Higher Lipid Accumulation Product Index |
title_full |
Reduced Fat Oxidation During Exercise in Post-Menopausal Overweight-Obese Women with Higher Lipid Accumulation Product Index |
title_fullStr |
Reduced Fat Oxidation During Exercise in Post-Menopausal Overweight-Obese Women with Higher Lipid Accumulation Product Index |
title_full_unstemmed |
Reduced Fat Oxidation During Exercise in Post-Menopausal Overweight-Obese Women with Higher Lipid Accumulation Product Index |
title_sort |
Reduced Fat Oxidation During Exercise in Post-Menopausal Overweight-Obese Women with Higher Lipid Accumulation Product Index |
author |
Stein, Elana |
author_facet |
Stein, Elana Silva, Igor Martins Dorneles, Gilson P. Lira, Fabio Santos [UNESP] Romão, Pedro Peres, Alessandra |
author_role |
author |
author2 |
Silva, Igor Martins Dorneles, Gilson P. Lira, Fabio Santos [UNESP] Romão, Pedro Peres, Alessandra |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
RS Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Stein, Elana Silva, Igor Martins Dorneles, Gilson P. Lira, Fabio Santos [UNESP] Romão, Pedro Peres, Alessandra |
description |
BACKGROUND AND AIMS: The main aim of this study was to analyze how the lipid accumulation affects the whole-body fat oxidation over a range of intensities during a submaximal incremental exercise test in post-menopausal overweight-obese women. PATIENTS AND METHODS: The maximal fat oxidation (MFO), the intensity where the MFO occurs (FatMax), fat oxidation were measured over a range of intensities during a submaximal incremental exercise test through indirect calorimetry in 60 postmenopausal overweight-obese women (aged>49 years; body mass index 28.0 to 39.0 kg/m²). The metabolic profile of participants was evaluated and the LAP index was calculated (waist-58×triglycerides [mmol/L]). A cutoff point of 34.5 was adopted and participant were designed as low LAP index (n=30) or high LAP index (n=30). RESULTS: During submaximal exercise postmenopausal overweight-obese women with low LAP index showed a higher fat oxidation at 50% (0.53±0.05 vs. 0.45±0.12 g/min; p=0.01), 60% (0.40±0.06 vs. 0.31±0.16 g/min; p=0.02) and 70% (0.34±0.08 vs. 0.25±0.15 g/min; p=0.03) of VO2Peak than those with high LAP index. No significant difference was observed in carbohydrate oxidation between groups (p>0.05) during exercise. Moreover, a significant difference in absolute MFO (p=0.018), MFO relative to free fat mass (p=0.043) and FatMax (p=0.002) was identified. CONCLUSION: Postmenopausal overweight-obese women who showed unhealthy metabolic phenotype evaluated through LAP index presented low fat oxidation during a submaximal incremental exercise. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T01:34:08Z 2020-12-12T01:34:08Z 2020-08-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1055/a-0801-8730 Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, v. 128, n. 8, p. 556-562, 2020. 1439-3646 http://hdl.handle.net/11449/199225 10.1055/a-0801-8730 2-s2.0-85089127946 |
url |
http://dx.doi.org/10.1055/a-0801-8730 http://hdl.handle.net/11449/199225 |
identifier_str_mv |
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, v. 128, n. 8, p. 556-562, 2020. 1439-3646 10.1055/a-0801-8730 2-s2.0-85089127946 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
556-562 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808128730386661376 |