Clinical assessment of nifedipine-induced gingival overgrowth in a group of brazilian patients
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.hindawi.com/journals/isrn/2011/102047/ http://hdl.handle.net/11449/125608 |
Resumo: | Although it has been established that nifedipine is associated with gingival overgrowth (GO), there is little information on the prevalence and severity of this condition in the Brazilian population. The aim of this study was to assess the occurrence of nifedipine-induced GO in Brazilian patients and the risk factors associated using a Clinical Index for Drug Induced Gingival Overgrowth (Clinical Index DIGO). The study was carried out on 35 patients under treatment with nifedipine (test group) and 35 patients without treatment (control group). Variables such as demographic (age, gender), pharmacological (dose, time of use), periodontal (plaque index, gingival index, probing depth, clinical insertion level, and bleeding on probing), and GO were assessed. Statistical analysis showed no association between GO and demographic or pharmacological variables. However, there was an association between GO and periodontal variables, except for plaque index. According to our study, the Clinical Index DIGO can be used as a parameter to evaluate GO. Therefore, we conclude that the presence of gingival inflammation was the main risk factor for the occurrence of nifedipine-induced GO. |
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Clinical assessment of nifedipine-induced gingival overgrowth in a group of brazilian patientsAlthough it has been established that nifedipine is associated with gingival overgrowth (GO), there is little information on the prevalence and severity of this condition in the Brazilian population. The aim of this study was to assess the occurrence of nifedipine-induced GO in Brazilian patients and the risk factors associated using a Clinical Index for Drug Induced Gingival Overgrowth (Clinical Index DIGO). The study was carried out on 35 patients under treatment with nifedipine (test group) and 35 patients without treatment (control group). Variables such as demographic (age, gender), pharmacological (dose, time of use), periodontal (plaque index, gingival index, probing depth, clinical insertion level, and bleeding on probing), and GO were assessed. Statistical analysis showed no association between GO and demographic or pharmacological variables. However, there was an association between GO and periodontal variables, except for plaque index. According to our study, the Clinical Index DIGO can be used as a parameter to evaluate GO. Therefore, we conclude that the presence of gingival inflammation was the main risk factor for the occurrence of nifedipine-induced GO.Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Diagnóstico e Cirurgia, Faculdade de Odontologia de Araraquara, Araraquara, R. Humaitá, 1680 - Centro, Centro, CEP 14801903, SP, BrasilUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Diagnóstico e Cirurgia, Faculdade de Odontologia de Araraquara, Araraquara, R. Humaitá, 1680 - Centro, Centro, CEP 14801903, SP, BrasilUniversidade Estadual Paulista (Unesp)Sousa, Cliciane Portela [UNESP]Navarro, Cláudia Maria [UNESP]Sposto, Maria Regina [UNESP]2015-08-06T16:12:36Z2015-08-06T16:12:36Z2011info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-5application/pdfhttp://www.hindawi.com/journals/isrn/2011/102047/International Scholarly Research Network Dentistry, v. 2011, p. 1-5, 2011.2090-4371http://hdl.handle.net/11449/12560810.5402/2011/102047ISSN2090-4371-2011-2011-01-05.pdf765023745925201031136068663863770000-0002-3185-2826Currículo Lattesreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengInternational Scholarly Research Network Dentistryinfo:eu-repo/semantics/openAccess2023-12-22T06:21:37Zoai:repositorio.unesp.br:11449/125608Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:00:04.926655Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Clinical assessment of nifedipine-induced gingival overgrowth in a group of brazilian patients |
title |
Clinical assessment of nifedipine-induced gingival overgrowth in a group of brazilian patients |
spellingShingle |
Clinical assessment of nifedipine-induced gingival overgrowth in a group of brazilian patients Sousa, Cliciane Portela [UNESP] |
title_short |
Clinical assessment of nifedipine-induced gingival overgrowth in a group of brazilian patients |
title_full |
Clinical assessment of nifedipine-induced gingival overgrowth in a group of brazilian patients |
title_fullStr |
Clinical assessment of nifedipine-induced gingival overgrowth in a group of brazilian patients |
title_full_unstemmed |
Clinical assessment of nifedipine-induced gingival overgrowth in a group of brazilian patients |
title_sort |
Clinical assessment of nifedipine-induced gingival overgrowth in a group of brazilian patients |
author |
Sousa, Cliciane Portela [UNESP] |
author_facet |
Sousa, Cliciane Portela [UNESP] Navarro, Cláudia Maria [UNESP] Sposto, Maria Regina [UNESP] |
author_role |
author |
author2 |
Navarro, Cláudia Maria [UNESP] Sposto, Maria Regina [UNESP] |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Sousa, Cliciane Portela [UNESP] Navarro, Cláudia Maria [UNESP] Sposto, Maria Regina [UNESP] |
description |
Although it has been established that nifedipine is associated with gingival overgrowth (GO), there is little information on the prevalence and severity of this condition in the Brazilian population. The aim of this study was to assess the occurrence of nifedipine-induced GO in Brazilian patients and the risk factors associated using a Clinical Index for Drug Induced Gingival Overgrowth (Clinical Index DIGO). The study was carried out on 35 patients under treatment with nifedipine (test group) and 35 patients without treatment (control group). Variables such as demographic (age, gender), pharmacological (dose, time of use), periodontal (plaque index, gingival index, probing depth, clinical insertion level, and bleeding on probing), and GO were assessed. Statistical analysis showed no association between GO and demographic or pharmacological variables. However, there was an association between GO and periodontal variables, except for plaque index. According to our study, the Clinical Index DIGO can be used as a parameter to evaluate GO. Therefore, we conclude that the presence of gingival inflammation was the main risk factor for the occurrence of nifedipine-induced GO. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011 2015-08-06T16:12:36Z 2015-08-06T16:12:36Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.hindawi.com/journals/isrn/2011/102047/ International Scholarly Research Network Dentistry, v. 2011, p. 1-5, 2011. 2090-4371 http://hdl.handle.net/11449/125608 10.5402/2011/102047 ISSN2090-4371-2011-2011-01-05.pdf 7650237459252010 3113606866386377 0000-0002-3185-2826 |
url |
http://www.hindawi.com/journals/isrn/2011/102047/ http://hdl.handle.net/11449/125608 |
identifier_str_mv |
International Scholarly Research Network Dentistry, v. 2011, p. 1-5, 2011. 2090-4371 10.5402/2011/102047 ISSN2090-4371-2011-2011-01-05.pdf 7650237459252010 3113606866386377 0000-0002-3185-2826 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
International Scholarly Research Network Dentistry |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1-5 application/pdf |
dc.source.none.fl_str_mv |
Currículo Lattes reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1808129272560222208 |