In vivo study of novel nanocomposite for prostate cancer treatment

Detalhes bibliográficos
Autor(a) principal: Silveira, C. P.
Data de Publicação: 2015
Outros Autores: Paula, A. J., Apolinário, L. M. [UNESP], Fávaro, W. J. [UNESP], Durán, N.
Tipo de documento: Artigo de conferência
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1088/1742-6596/617/1/012001
http://hdl.handle.net/11449/168401
Resumo: Because of high occurrence of side effects of conventional anticancer drugs, new therapies have been widely studied, such as the use of non-usual molecules and the association with nanomaterials. In this context, sildenafil is a molecule that has been lately considered as a co-adjuvant in cancer therapy because it inhibits an enzyme with a potential role in tumor progression, phosphodiesterase-5. Taking into account the combination of nanoparticles and sildenafil, we produced systems based on mesoporoussilica nanoparticles, Pluronic F-127 and sildenafil as the main therapy for prostate cancer.
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spelling In vivo study of novel nanocomposite for prostate cancer treatmentBecause of high occurrence of side effects of conventional anticancer drugs, new therapies have been widely studied, such as the use of non-usual molecules and the association with nanomaterials. In this context, sildenafil is a molecule that has been lately considered as a co-adjuvant in cancer therapy because it inhibits an enzyme with a potential role in tumor progression, phosphodiesterase-5. Taking into account the combination of nanoparticles and sildenafil, we produced systems based on mesoporoussilica nanoparticles, Pluronic F-127 and sildenafil as the main therapy for prostate cancer.Chemistry Institute Universidade Estadual de Campinas (UNICAMP) Campus Universitário Zeferino Vaz, s/n, Cidade UniversitáriaDepartment of Physics Universidade Federal Do Ceará (UFC), Avenida da Universidade, Benfica, CEP 60020-181, CEDepartment of Environmental Engineering Universidade Estadual Paulista (UNESP), Avenida Trěs de Março, CEP 18087-180, SPFarmabrasilis R and D DivisionNanobioss Chemistry Institute Universidade Estadual de Campinas (UNICAMP) Campus Universitário Zeferino Vaz, s/n, Cidade UniversitáriaDepartment of Environmental Engineering Universidade Estadual Paulista (UNESP), Avenida Trěs de Março, CEP 18087-180, SPUniversidade Estadual de Campinas (UNICAMP)Universidade Federal Do Ceará (UFC)Universidade Estadual Paulista (Unesp)Farmabrasilis R and D DivisionSilveira, C. P.Paula, A. J.Apolinário, L. M. [UNESP]Fávaro, W. J. [UNESP]Durán, N.2018-12-11T16:41:07Z2018-12-11T16:41:07Z2015-05-26info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectapplication/pdfhttp://dx.doi.org/10.1088/1742-6596/617/1/012001Journal of Physics: Conference Series, v. 617, n. 1, 2015.1742-65961742-6588http://hdl.handle.net/11449/16840110.1088/1742-6596/617/1/0120012-s2.0-849586175742-s2.0-84958617574.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Physics: Conference Series0,2410,241info:eu-repo/semantics/openAccess2023-11-22T06:17:32Zoai:repositorio.unesp.br:11449/168401Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T18:26:50.989308Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv In vivo study of novel nanocomposite for prostate cancer treatment
title In vivo study of novel nanocomposite for prostate cancer treatment
spellingShingle In vivo study of novel nanocomposite for prostate cancer treatment
Silveira, C. P.
title_short In vivo study of novel nanocomposite for prostate cancer treatment
title_full In vivo study of novel nanocomposite for prostate cancer treatment
title_fullStr In vivo study of novel nanocomposite for prostate cancer treatment
title_full_unstemmed In vivo study of novel nanocomposite for prostate cancer treatment
title_sort In vivo study of novel nanocomposite for prostate cancer treatment
author Silveira, C. P.
author_facet Silveira, C. P.
Paula, A. J.
Apolinário, L. M. [UNESP]
Fávaro, W. J. [UNESP]
Durán, N.
author_role author
author2 Paula, A. J.
Apolinário, L. M. [UNESP]
Fávaro, W. J. [UNESP]
Durán, N.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual de Campinas (UNICAMP)
Universidade Federal Do Ceará (UFC)
Universidade Estadual Paulista (Unesp)
Farmabrasilis R and D Division
dc.contributor.author.fl_str_mv Silveira, C. P.
Paula, A. J.
Apolinário, L. M. [UNESP]
Fávaro, W. J. [UNESP]
Durán, N.
description Because of high occurrence of side effects of conventional anticancer drugs, new therapies have been widely studied, such as the use of non-usual molecules and the association with nanomaterials. In this context, sildenafil is a molecule that has been lately considered as a co-adjuvant in cancer therapy because it inhibits an enzyme with a potential role in tumor progression, phosphodiesterase-5. Taking into account the combination of nanoparticles and sildenafil, we produced systems based on mesoporoussilica nanoparticles, Pluronic F-127 and sildenafil as the main therapy for prostate cancer.
publishDate 2015
dc.date.none.fl_str_mv 2015-05-26
2018-12-11T16:41:07Z
2018-12-11T16:41:07Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/conferenceObject
format conferenceObject
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1088/1742-6596/617/1/012001
Journal of Physics: Conference Series, v. 617, n. 1, 2015.
1742-6596
1742-6588
http://hdl.handle.net/11449/168401
10.1088/1742-6596/617/1/012001
2-s2.0-84958617574
2-s2.0-84958617574.pdf
url http://dx.doi.org/10.1088/1742-6596/617/1/012001
http://hdl.handle.net/11449/168401
identifier_str_mv Journal of Physics: Conference Series, v. 617, n. 1, 2015.
1742-6596
1742-6588
10.1088/1742-6596/617/1/012001
2-s2.0-84958617574
2-s2.0-84958617574.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Physics: Conference Series
0,241
0,241
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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