Sepse em felinos

• Autor(a) principal: Chacar, Fernanda Chicharo [UNESP]
• Data de Publicação: 2014
• Outros Autores: Okamoto, Priscylla Tatiana Chalfun Guimarães [UNESP], Melchert, Alessandra [UNESP], Arruda, Vanesa Kutz de [UNESP], Bento, Daniel Diola [UNESP], Costa, Denis Carvalho [UNESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://www.fmvz.unesp.br/rvz/index.php/rvz/article/view/515; http://hdl.handle.net/11449/140509
• topic: SIRS; Cats; Septic shock; Pathophysiology; SRIS; Gatos; Shock séptico; Fisiopatología; SRIS; Gatos; Choque séptico; Fisiopatologia

Sepsis, defined as the systemic inflammatory response syndrome (SIRS) due to an infectious agent, is a common condition in cats and it is related to high morbidity and high mortality in this specie. Its main causes are pyothorax and septic peritonitis in felines. Due to its anatomical and physiological peculiarities, cats react uniquely to sepsis, presenting bradycardia, hypotension and hypothermia, signs that compound the "Shock triad in cats." The main inflammatory mediators of sepsis in this specie are TNF, IL-10, IL-6 and CXCL-8. The diagnosis of sepsis or severe sepsis is mainly based on clinical findings. The treatment of this syndrome in feline specie should be based on the “Goal-directed therapy”, wich involves intensive monitoring and aggressive management of hemodynamics in patients at high risk. Although sepsis causes high rates of morbidity and mortality in cats, few studies about the etiology, pathophysiology, hemodynamic and metabolic changes are available. Greater efforts are needed by the veterinary community to understand this complex syndrome in cats, due to its peculiarities and due to its increase population in Brazil in the last times.