A new surgical technique to treat corneal perforations using amniotic membrane and surgical adhesive
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2014 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNESP |
| Texto Completo: | http://dx.doi.org/10.1590/1678-41625707 http://hdl.handle.net/11449/114167 |
Resumo: | The objectives of this study were to compare surgical techniques and the effects of using n-butyl 2-cyanoacrylate and bovine amniotic membrane to repair perforated lesions in corneas. Penetrating keratoplasty was performed in sixty New Zealand White rabbits under general anesthesia. Group 1 (G1) was treated with n-butyl 2-cyanoacrylate, group 2 (G2) received a fragment of amniotic membrane through the anterior chamber and application of n-butyl 2-cyanoacrylate over the lesion, group 3 (G3) was treated with the same technique as G2 with the addition of an amniotic membrane bandage covering the cornea and sutured in the limbus region, and group 4 (G4) was treated with an amniotic membrane sutured to the lesion and an amniotic membrane bandage sutured in the limbus region. Clinical, histological and histomorphometric examinations of the corneas were performed. The membrane acted as a barrier for aqueous humor in G2 and G3, thereby keeping the surface dry for adhesive application; it also prevented the adhesive from contacting intraocular structures. The groups treated with amniotic membrane and surgical adhesive showed better results than the groups treated with either material alone. Thus, the combination of the membrane with the adhesive is recommended for this type of lesion. |
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A new surgical technique to treat corneal perforations using amniotic membrane and surgical adhesiveNova técnica cirúrgica para tratamento de perfuração de córnea utilizando membrana amniótica e adesivo cirúrgicoCoelhosCórneaCianoacrilatoGlicerinaCirurgia oftálmicaRabbitsCorneaCyanoacrylateGlycerinOphthalmic surgeryThe objectives of this study were to compare surgical techniques and the effects of using n-butyl 2-cyanoacrylate and bovine amniotic membrane to repair perforated lesions in corneas. Penetrating keratoplasty was performed in sixty New Zealand White rabbits under general anesthesia. Group 1 (G1) was treated with n-butyl 2-cyanoacrylate, group 2 (G2) received a fragment of amniotic membrane through the anterior chamber and application of n-butyl 2-cyanoacrylate over the lesion, group 3 (G3) was treated with the same technique as G2 with the addition of an amniotic membrane bandage covering the cornea and sutured in the limbus region, and group 4 (G4) was treated with an amniotic membrane sutured to the lesion and an amniotic membrane bandage sutured in the limbus region. Clinical, histological and histomorphometric examinations of the corneas were performed. The membrane acted as a barrier for aqueous humor in G2 and G3, thereby keeping the surface dry for adhesive application; it also prevented the adhesive from contacting intraocular structures. The groups treated with amniotic membrane and surgical adhesive showed better results than the groups treated with either material alone. Thus, the combination of the membrane with the adhesive is recommended for this type of lesion.Os objetivos deste estudo foram comparar técnicas cirúrgicas e efeitos do n-butil 2-cianoacrilato e da membrana amniótica bovina na reparação de lesões perfuradas em córneas. Sessenta coelhos da raça Nova Zelândia Branca foram submetidos à ceratoplastia penetrante sob anestesia geral. O grupo 1 (G1) foi tratado com n-butil 2-cianoacrilato; o grupo 2 (G2) recebeu um fragmento de membrana amniótica pela câmara anterior e aplicação de n-butil 2-cianoacrilato sobre a lesão; o grupo 3 (G3) foi tratado com a mesma técnica aplicada ao G2, adicionando-se uma bandagem de membrana amniótica cobrindo a córnea e suturada à região do limbo; e o grupo 4 (G4) foi tratado com membrana amniótica suturada nas bordas da lesão e bandagem de membrana amniótica suturada na região do limbo. Foram realizados exames clínico, histológico e histomorfométrico. A membrana atuou como barreira contra o extravasamento do humor aquoso nos grupos 2 e 3, manteve a superfície seca para posterior aplicação do adesivo e impediu o contato do adesivo com as estruturas intraoculares. Os grupos tratados com o adesivo associado à membrana amniótica demonstraram melhores resultados do que aqueles tratados com cada material isoladamente. Assim, a combinação da membrana com o adesivo é indicada neste tipo de lesão.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Federal de ViçosaUNESP Faculdade de Ciências Agrárias e VeterináriasUNESP Faculdade de Ciências Agrárias e VeterináriasUniversidade Federal de Minas Gerais, Escola de VeterináriaUniversidade Federal de Viçosa (UFV)Universidade Estadual Paulista (Unesp)Pontes, Kelly Cristine de SouzaBorges, Andréa Pacheco BatistaEleotério, Renato BarrosFrazão, Ana Carolina do NascimentoMachado, Daniel Portela DiasReis, Emily Correna CarloSepúlveda, Rodrigo VianaDuarte, Tarcísio de SouzaLaus, José Luiz [UNESP]2015-02-02T12:39:18Z2015-02-02T12:39:18Z2014-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article655-664application/pdfhttp://dx.doi.org/10.1590/1678-41625707Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Universidade Federal de Minas Gerais, Escola de Veterinária, v. 66, n. 3, p. 655-664, 2014.0102-0935http://hdl.handle.net/11449/11416710.1590/1678-41625707S0102-09352014000300655S0102-09352014000300655.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengArquivo Brasileiro de Medicina Veterinária e Zootecnia0.2860,248info:eu-repo/semantics/openAccess2023-12-26T06:22:55Zoai:repositorio.unesp.br:11449/114167Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-12-26T06:22:55Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
| dc.title.none.fl_str_mv |
A new surgical technique to treat corneal perforations using amniotic membrane and surgical adhesive Nova técnica cirúrgica para tratamento de perfuração de córnea utilizando membrana amniótica e adesivo cirúrgico |
| title |
A new surgical technique to treat corneal perforations using amniotic membrane and surgical adhesive |
| spellingShingle |
A new surgical technique to treat corneal perforations using amniotic membrane and surgical adhesive Pontes, Kelly Cristine de Souza Coelhos Córnea Cianoacrilato Glicerina Cirurgia oftálmica Rabbits Cornea Cyanoacrylate Glycerin Ophthalmic surgery |
| title_short |
A new surgical technique to treat corneal perforations using amniotic membrane and surgical adhesive |
| title_full |
A new surgical technique to treat corneal perforations using amniotic membrane and surgical adhesive |
| title_fullStr |
A new surgical technique to treat corneal perforations using amniotic membrane and surgical adhesive |
| title_full_unstemmed |
A new surgical technique to treat corneal perforations using amniotic membrane and surgical adhesive |
| title_sort |
A new surgical technique to treat corneal perforations using amniotic membrane and surgical adhesive |
| author |
Pontes, Kelly Cristine de Souza |
| author_facet |
Pontes, Kelly Cristine de Souza Borges, Andréa Pacheco Batista Eleotério, Renato Barros Frazão, Ana Carolina do Nascimento Machado, Daniel Portela Dias Reis, Emily Correna Carlo Sepúlveda, Rodrigo Viana Duarte, Tarcísio de Souza Laus, José Luiz [UNESP] |
| author_role |
author |
| author2 |
Borges, Andréa Pacheco Batista Eleotério, Renato Barros Frazão, Ana Carolina do Nascimento Machado, Daniel Portela Dias Reis, Emily Correna Carlo Sepúlveda, Rodrigo Viana Duarte, Tarcísio de Souza Laus, José Luiz [UNESP] |
| author2_role |
author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade Federal de Viçosa (UFV) Universidade Estadual Paulista (Unesp) |
| dc.contributor.author.fl_str_mv |
Pontes, Kelly Cristine de Souza Borges, Andréa Pacheco Batista Eleotério, Renato Barros Frazão, Ana Carolina do Nascimento Machado, Daniel Portela Dias Reis, Emily Correna Carlo Sepúlveda, Rodrigo Viana Duarte, Tarcísio de Souza Laus, José Luiz [UNESP] |
| dc.subject.por.fl_str_mv |
Coelhos Córnea Cianoacrilato Glicerina Cirurgia oftálmica Rabbits Cornea Cyanoacrylate Glycerin Ophthalmic surgery |
| topic |
Coelhos Córnea Cianoacrilato Glicerina Cirurgia oftálmica Rabbits Cornea Cyanoacrylate Glycerin Ophthalmic surgery |
| description |
The objectives of this study were to compare surgical techniques and the effects of using n-butyl 2-cyanoacrylate and bovine amniotic membrane to repair perforated lesions in corneas. Penetrating keratoplasty was performed in sixty New Zealand White rabbits under general anesthesia. Group 1 (G1) was treated with n-butyl 2-cyanoacrylate, group 2 (G2) received a fragment of amniotic membrane through the anterior chamber and application of n-butyl 2-cyanoacrylate over the lesion, group 3 (G3) was treated with the same technique as G2 with the addition of an amniotic membrane bandage covering the cornea and sutured in the limbus region, and group 4 (G4) was treated with an amniotic membrane sutured to the lesion and an amniotic membrane bandage sutured in the limbus region. Clinical, histological and histomorphometric examinations of the corneas were performed. The membrane acted as a barrier for aqueous humor in G2 and G3, thereby keeping the surface dry for adhesive application; it also prevented the adhesive from contacting intraocular structures. The groups treated with amniotic membrane and surgical adhesive showed better results than the groups treated with either material alone. Thus, the combination of the membrane with the adhesive is recommended for this type of lesion. |
| publishDate |
2014 |
| dc.date.none.fl_str_mv |
2014-06-01 2015-02-02T12:39:18Z 2015-02-02T12:39:18Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1678-41625707 Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Universidade Federal de Minas Gerais, Escola de Veterinária, v. 66, n. 3, p. 655-664, 2014. 0102-0935 http://hdl.handle.net/11449/114167 10.1590/1678-41625707 S0102-09352014000300655 S0102-09352014000300655.pdf |
| url |
http://dx.doi.org/10.1590/1678-41625707 http://hdl.handle.net/11449/114167 |
| identifier_str_mv |
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Universidade Federal de Minas Gerais, Escola de Veterinária, v. 66, n. 3, p. 655-664, 2014. 0102-0935 10.1590/1678-41625707 S0102-09352014000300655 S0102-09352014000300655.pdf |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
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Arquivo Brasileiro de Medicina Veterinária e Zootecnia 0.286 0,248 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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655-664 application/pdf |
| dc.publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
| publisher.none.fl_str_mv |
Universidade Federal de Minas Gerais, Escola de Veterinária |
| dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
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Universidade Estadual Paulista (UNESP) |
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UNESP |
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UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
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|
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1799965417986326528 |