Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbits

Detalhes bibliográficos
Autor(a) principal: Serna‐garcía, Marta [UNESP]
Data de Publicação: 2020
Outros Autores: Peiró, Rosa, Serna, Eva, Santacreu, María Antonia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.3390/ani10101924
http://hdl.handle.net/11449/205361
Resumo: Litter size is an essential trait in rabbit meat production but with low heritability. A selection experiment for ovulation rate has been performed for 10 generations to improve litter size in rabbits. The selected line increased two ova more than the control line but nevertheless a negative correlation was observed with prenatal survival. A transcriptomic study was performed, using microarrays, in ovarian tissue from females belonging to the selected line and the control line. Our results showed 1357 differential expressed genes and nineteen potential biomarkers associated with prenatal mortality, which could explain differences between litter size in rabbits. Cell death was the most relevant process.
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spelling Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbitsLitter sizeOvarian tissueOvulation rateRabbitTranscriptomic analysisLitter size is an essential trait in rabbit meat production but with low heritability. A selection experiment for ovulation rate has been performed for 10 generations to improve litter size in rabbits. The selected line increased two ova more than the control line but nevertheless a negative correlation was observed with prenatal survival. A transcriptomic study was performed, using microarrays, in ovarian tissue from females belonging to the selected line and the control line. Our results showed 1357 differential expressed genes and nineteen potential biomarkers associated with prenatal mortality, which could explain differences between litter size in rabbits. Cell death was the most relevant process.Generalitat ValencianaMinistério da Educação e CiênciaInstituto de Ciencia y Tecnología Animal Universitat Politècnica de ValènciaFaculty of Agricultural and Veterinary Sciences São Paulo State University FCAV/UNESPInstituto de Conservación y Mejora de la Agrodiversidad Valenciana Universitat Politècnica de ValènciaDepartment of Physiology Faculty of Medicine University of ValenciaFaculty of Agricultural and Veterinary Sciences São Paulo State University FCAV/UNESPGeneralitat Valenciana: 2009/125Ministério da Educação e Ciência: AGL2014‐55921‐C2‐1‐PUniversitat Politècnica de ValènciaUniversidade Estadual Paulista (Unesp)University of ValenciaSerna‐garcía, Marta [UNESP]Peiró, RosaSerna, EvaSantacreu, María Antonia2021-06-25T10:14:03Z2021-06-25T10:14:03Z2020-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-12http://dx.doi.org/10.3390/ani10101924Animals, v. 10, n. 10, p. 1-12, 2020.2076-2615http://hdl.handle.net/11449/20536110.3390/ani101019242-s2.0-85093663113Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAnimalsinfo:eu-repo/semantics/openAccess2021-10-23T12:39:37Zoai:repositorio.unesp.br:11449/205361Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T21:22:16.457838Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbits
title Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbits
spellingShingle Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbits
Serna‐garcía, Marta [UNESP]
Litter size
Ovarian tissue
Ovulation rate
Rabbit
Transcriptomic analysis
title_short Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbits
title_full Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbits
title_fullStr Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbits
title_full_unstemmed Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbits
title_sort Ovarian transcriptomic analysis reveals differential expression genes associated with cell death process after selection for ovulation rate in rabbits
author Serna‐garcía, Marta [UNESP]
author_facet Serna‐garcía, Marta [UNESP]
Peiró, Rosa
Serna, Eva
Santacreu, María Antonia
author_role author
author2 Peiró, Rosa
Serna, Eva
Santacreu, María Antonia
author2_role author
author
author
dc.contributor.none.fl_str_mv Universitat Politècnica de València
Universidade Estadual Paulista (Unesp)
University of Valencia
dc.contributor.author.fl_str_mv Serna‐garcía, Marta [UNESP]
Peiró, Rosa
Serna, Eva
Santacreu, María Antonia
dc.subject.por.fl_str_mv Litter size
Ovarian tissue
Ovulation rate
Rabbit
Transcriptomic analysis
topic Litter size
Ovarian tissue
Ovulation rate
Rabbit
Transcriptomic analysis
description Litter size is an essential trait in rabbit meat production but with low heritability. A selection experiment for ovulation rate has been performed for 10 generations to improve litter size in rabbits. The selected line increased two ova more than the control line but nevertheless a negative correlation was observed with prenatal survival. A transcriptomic study was performed, using microarrays, in ovarian tissue from females belonging to the selected line and the control line. Our results showed 1357 differential expressed genes and nineteen potential biomarkers associated with prenatal mortality, which could explain differences between litter size in rabbits. Cell death was the most relevant process.
publishDate 2020
dc.date.none.fl_str_mv 2020-10-01
2021-06-25T10:14:03Z
2021-06-25T10:14:03Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3390/ani10101924
Animals, v. 10, n. 10, p. 1-12, 2020.
2076-2615
http://hdl.handle.net/11449/205361
10.3390/ani10101924
2-s2.0-85093663113
url http://dx.doi.org/10.3390/ani10101924
http://hdl.handle.net/11449/205361
identifier_str_mv Animals, v. 10, n. 10, p. 1-12, 2020.
2076-2615
10.3390/ani10101924
2-s2.0-85093663113
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Animals
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1-12
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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