Tomografia por biosusceptometria de corrente alternada

Detalhes bibliográficos
Autor(a) principal: Fonseca Filho, Paulo Roberto da [UNESP]
Data de Publicação: 2014
Tipo de documento: Tese
Idioma: por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://hdl.handle.net/11449/123264
Resumo: The development of new imaging methods, especially those that are free of ionizing radiation, constitute a very important topic because for both instrumentation development and its applications. The Alternating Current Biosusceptometry (ACB) has versatility, sensibility and low cost and has been widely used on image acquisition on gastroenterology, physiology, pharmaceutics and pharmacology researches. The aim of this project was to characterize ACB systems to produce tomographic images of simulating objects ver-ifying the technical viability of the AC Biosusceptometry Tomography (ACBT). The capability of ACB gradiometers of 13 and 37 channel systems with compensation field to reconstruct images of bars and cy-lindrical phantoms were evaluated, especially sensibility and resolution. It was possible to reconstruct im-ages from all objects with good correlation between the image and the phantom (geometry and magnetic tracer concentration). Better results were observed while using multichannel acquisition on 37-channel sys-tem with active excitation magnetic field. Therefore we verified that ACB systems can be successfully used on tomographic imaging of objects with small quantities of magnetic tracer, which is viable to future ap-plication on small animal physiology, pharmaceutics or non-destructive evaluation research
id UNSP_430c88bbdfcd9c68a3ed53c241975f33
oai_identifier_str oai:repositorio.unesp.br:11449/123264
network_acronym_str UNSP
network_name_str Repositório Institucional da UNESP
repository_id_str 2946
spelling Tomografia por biosusceptometria de corrente alternadaTomografiaBiosusceptometria de Corrente AlternadaBiomagnetismoAlternated Current BiosusceptometryThe development of new imaging methods, especially those that are free of ionizing radiation, constitute a very important topic because for both instrumentation development and its applications. The Alternating Current Biosusceptometry (ACB) has versatility, sensibility and low cost and has been widely used on image acquisition on gastroenterology, physiology, pharmaceutics and pharmacology researches. The aim of this project was to characterize ACB systems to produce tomographic images of simulating objects ver-ifying the technical viability of the AC Biosusceptometry Tomography (ACBT). The capability of ACB gradiometers of 13 and 37 channel systems with compensation field to reconstruct images of bars and cy-lindrical phantoms were evaluated, especially sensibility and resolution. It was possible to reconstruct im-ages from all objects with good correlation between the image and the phantom (geometry and magnetic tracer concentration). Better results were observed while using multichannel acquisition on 37-channel sys-tem with active excitation magnetic field. Therefore we verified that ACB systems can be successfully used on tomographic imaging of objects with small quantities of magnetic tracer, which is viable to future ap-plication on small animal physiology, pharmaceutics or non-destructive evaluation researchA busca por novos métodos de imagens, principalmente os livres de radiação ionizante, são importantes tanto pelas instrumentações, quanto para as finalidades. A Biosusceptometria de |Corrente Alternada (BAC) possui versatilidade, sensibilidade, baixo custo e têm sido amplamente utilizada na aquisição de imagens para estudos nas áreas de gastrenterologia, fisiologia, farmacologia e farmácia. O objetivo deste trabalho foi caracterizar sistemas de BAC na produção de imagens tomográficas de objetos simuladores, propondo a viabilidade da técnica de tBAC - tomografia por biosusceptometria de Corrente Alternada. Para tanto, os gradiômetros de dois sistemas BAC com 13 e 37 canais com compensação de campo de excitação foram avaliados quanto à sua sensibilidade e resolução para produzir imagens de simuladores de barras e cilíndri-cos. Foi possível reconstruir imagens de todos os objetos com boa correlação entre a imagem e as caracte-rísticas físicas dos objetos (forma e concentração de traçador magnético). As melhores imagens foram pro-duzidas quando foi utilizada aquisição multicanal no sistema de BAC com 37 sensores utilizando compen-sação de campo, os quais possuem menores diâmetros. Dessa forma verificou-se que os sistemas BAC podem ser empregados com sucesso para produzir imagens tomográficas de objetos com pequena quanti-dade de traçador magnético, o que viabiliza sua aplicação futura em pequenos animais, farmacotecnia ou ainda ensaios não destrutivosCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Estadual Paulista (Unesp)Miranda, José Ricardo de Arruda [UNESP]Universidade Estadual Paulista (Unesp)Fonseca Filho, Paulo Roberto da [UNESP]2015-05-14T16:53:14Z2015-05-14T16:53:14Z2014-02-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis66 f.application/pdfFONSECA FILHO, Paulo Roberto da. Tomografia por biosusceptometria de corrente alternada. 2014. 66 f. Tese (doutorado) - Universidade Estadual Paulista Júlio de Mesquita Filho, Instituto de Biociências de Botucatu, 2014.http://hdl.handle.net/11449/123264000822024000822024.pdf33004064080P3Alephreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporinfo:eu-repo/semantics/openAccess2024-01-18T06:28:48Zoai:repositorio.unesp.br:11449/123264Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:21:55.316381Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Tomografia por biosusceptometria de corrente alternada
title Tomografia por biosusceptometria de corrente alternada
spellingShingle Tomografia por biosusceptometria de corrente alternada
Fonseca Filho, Paulo Roberto da [UNESP]
Tomografia
Biosusceptometria de Corrente Alternada
Biomagnetismo
Alternated Current Biosusceptometry
title_short Tomografia por biosusceptometria de corrente alternada
title_full Tomografia por biosusceptometria de corrente alternada
title_fullStr Tomografia por biosusceptometria de corrente alternada
title_full_unstemmed Tomografia por biosusceptometria de corrente alternada
title_sort Tomografia por biosusceptometria de corrente alternada
author Fonseca Filho, Paulo Roberto da [UNESP]
author_facet Fonseca Filho, Paulo Roberto da [UNESP]
author_role author
dc.contributor.none.fl_str_mv Miranda, José Ricardo de Arruda [UNESP]
Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Fonseca Filho, Paulo Roberto da [UNESP]
dc.subject.por.fl_str_mv Tomografia
Biosusceptometria de Corrente Alternada
Biomagnetismo
Alternated Current Biosusceptometry
topic Tomografia
Biosusceptometria de Corrente Alternada
Biomagnetismo
Alternated Current Biosusceptometry
description The development of new imaging methods, especially those that are free of ionizing radiation, constitute a very important topic because for both instrumentation development and its applications. The Alternating Current Biosusceptometry (ACB) has versatility, sensibility and low cost and has been widely used on image acquisition on gastroenterology, physiology, pharmaceutics and pharmacology researches. The aim of this project was to characterize ACB systems to produce tomographic images of simulating objects ver-ifying the technical viability of the AC Biosusceptometry Tomography (ACBT). The capability of ACB gradiometers of 13 and 37 channel systems with compensation field to reconstruct images of bars and cy-lindrical phantoms were evaluated, especially sensibility and resolution. It was possible to reconstruct im-ages from all objects with good correlation between the image and the phantom (geometry and magnetic tracer concentration). Better results were observed while using multichannel acquisition on 37-channel sys-tem with active excitation magnetic field. Therefore we verified that ACB systems can be successfully used on tomographic imaging of objects with small quantities of magnetic tracer, which is viable to future ap-plication on small animal physiology, pharmaceutics or non-destructive evaluation research
publishDate 2014
dc.date.none.fl_str_mv 2014-02-03
2015-05-14T16:53:14Z
2015-05-14T16:53:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv FONSECA FILHO, Paulo Roberto da. Tomografia por biosusceptometria de corrente alternada. 2014. 66 f. Tese (doutorado) - Universidade Estadual Paulista Júlio de Mesquita Filho, Instituto de Biociências de Botucatu, 2014.
http://hdl.handle.net/11449/123264
000822024
000822024.pdf
33004064080P3
identifier_str_mv FONSECA FILHO, Paulo Roberto da. Tomografia por biosusceptometria de corrente alternada. 2014. 66 f. Tese (doutorado) - Universidade Estadual Paulista Júlio de Mesquita Filho, Instituto de Biociências de Botucatu, 2014.
000822024
000822024.pdf
33004064080P3
url http://hdl.handle.net/11449/123264
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 66 f.
application/pdf
dc.publisher.none.fl_str_mv Universidade Estadual Paulista (Unesp)
publisher.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.source.none.fl_str_mv Aleph
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129510947684352

Registros relacionados