Proteínas derivadas da matriz de esmalte e laser de baixa intensidade na regeneração periodontal: revisão de literatura

• Autor(a) principal: Jorge, Paula Karine [UNESP]
• Data de Publicação: 2009
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://hdl.handle.net/11449/202954; http://www.athena.biblioteca.unesp.br/exlibris/bd/capelo/2018-10-22/000908077.pdf
• topic: Esmalte dentário; Lasers; Regeneração tecidual guiada; Dental enamel

The regeneration of the periodontal tissues is dependent on four basic componetes such as appropriate signals, cells, blood supply and scaffold. Each of these elements plays a fundamental role on the healing process in a simultaneous and temporal time frame and is interconnected into the generation of new tissues (TABA et al., 2005). One therapeutic modality available to promote periodontal regeneration is the use of enamel matrix derivative proteins (EMD). These proteins are used with the purpose to mimic specific events that occur in the natural development of the periodontal supporting tissues during odontogenesis (GIANNOBILE et al., 2003; HAMMARSTROM, 1997a; HAMMARSTRÖM et al., 1997b) such as the attachment of cementum to root dentin (TEN CATE, 1996), initiation of cementogenesis (HERITIER, 1982) and induction of the differentiation of the dental follicle cells to cementoblasts (HAMMARSTRÖM, 1997a). There are evidences that enamel proteins have the capacity to promote true periodontal regeneration by inducing the formation of new acellular cementum, periodontal ligament and alveolar bone (KAWASE et al., 2000). Another terapheutic modality proposed to promote tissue regeneration that has been recently evaluated is the use of low level intensity laser irradiation (LLLI). LLLI acts on tissue biomodulation (NICOLAU et al., 2003), inducing intra-cellular metabolic alterations, as well as accelerating cell division, migration and proliferation of fibroblasts (KHADRA, 2005; KHADRA 2005a; KREISLER, 2002). The use of LLLI as well as of EMD have demonstrated potential attributes that may contribute to periodontal regeneration. The purpose of this study is to discuss the use of both terapheutic modalities for periodontal regeneration