Evaluación del comportamiento biológico de tres cementos obturadores endodónticos en tejido subcutáneo de ratones
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | spa |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.actaodontologica.com/ediciones/2012/3/art8.asp http://hdl.handle.net/11449/125862 |
Resumo: | The aim of this study was to evaluate the biological behavior of the root canal filling sealers: Endofill, Endomethasone and Sealer 26 when in contact with the subcutaneous connective tissue of rat. For the study one control and three experimental groups were used. A total of 15 animals were divided into 5 for each period: 7, 21, and 60 days. The obtained histological sections were processed and stained using the hematoxiline & eosine technique. The histological sections were subjective and comparatively analyzed using optic microscopy. The intensity of the inflammatory reaction and the level of fibrosis of the tissue were registered. The results were registered in scores and statistical analysis by KRUSKAL-WALLIS p<0,05 and MILLER methods. The statistical analysis revealed that in the period of 60 days, there was statistical significance to group II (Endofill) between group (control) and III (Endomethasone) with mononuclear cells into connective tissue. All materials promoted inflammatory reaction more intense at 7 and 21 days with the Endomethasone showing the best results. |
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Evaluación del comportamiento biológico de tres cementos obturadores endodónticos en tejido subcutáneo de ratonesRoot canal obturationToxicityEndodontic sealersObturación del conducto radicularBiocompatibilidadCementos endodónticosThe aim of this study was to evaluate the biological behavior of the root canal filling sealers: Endofill, Endomethasone and Sealer 26 when in contact with the subcutaneous connective tissue of rat. For the study one control and three experimental groups were used. A total of 15 animals were divided into 5 for each period: 7, 21, and 60 days. The obtained histological sections were processed and stained using the hematoxiline & eosine technique. The histological sections were subjective and comparatively analyzed using optic microscopy. The intensity of the inflammatory reaction and the level of fibrosis of the tissue were registered. The results were registered in scores and statistical analysis by KRUSKAL-WALLIS p<0,05 and MILLER methods. The statistical analysis revealed that in the period of 60 days, there was statistical significance to group II (Endofill) between group (control) and III (Endomethasone) with mononuclear cells into connective tissue. All materials promoted inflammatory reaction more intense at 7 and 21 days with the Endomethasone showing the best results.El objetivo de este estudio fue evaluar el comportamiento biológico de los cementos endodónticos Endofill, Endomethasone y Sealer 26, en tejido conjuntivo subcutáneo de ratones. Fueron establecidos tres grupos experimentales y un grupo control de cinco animales cada uno, en los períodos de 7, 21 y 60 días. Los cortes histológicos obtenidos fueron coloreados con Hematoxilina & Eosina y con tricrómico de Masson, para posteriormente ser evaluadas la reacción inflamatoria adyacente y la formación de tejido fibroso. Los datos obtenidos fueron sometidos al test estadístico de Kruskall-Wallis y Miller con 5% de nivel de significancia. El análisis microscópico mostró reacción inflamatoria más intensa en los períodos de 7 y 21días. A los 60 días hubo formación de una cápsula fibrosa densa para el cemento Endomethasone y parcialmente densa para los demás cementos. El análisis estadístico mostró diferencia estadísticamente significativa con mayor intensidad de reacción inflamatoria solamente para el grupo II (Endofill) en el período de 60 días en relación a los grupos I (control) y grupo III (Endomethasone). Todos los materiales presentaron reacción inflamatoria más intensa en los períodos inicial e intermediario, siendo que la Endomethasone presentó los mejores resultados.Universidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Odontologia Restauradora, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá nº 1680, Centro, CEP 14801-903, SP, BrasilEndodontics, Curitiba Dental School, Federal University of Paraná (UFPR), Curitiba, PR, BrazilUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Odontologia Restauradora, Faculdade de Odontologia de Araraquara, Araraquara, Rua Humaitá nº 1680, Centro, CEP 14801-903, SP, BrasilUniversidade Estadual Paulista (Unesp)Universidade Federal do Paraná (UFPR)Moraes, Sergio HerreroTanomaru Filho, Mario [UNESP]Chavez-Andrade, Gisele Moraima [UNESP]Silva, Guilherme Ferreira da [UNESP]Tanomaru, Juliane Mario Guerreiro [UNESP]2015-08-06T16:13:18Z2015-08-06T16:13:18Z2012info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2-6http://www.actaodontologica.com/ediciones/2012/3/art8.aspActa Odontológica Venezolana, v. 50, n. 3, p. 2-6, 2012.0001-6365http://hdl.handle.net/11449/12586226652112985847511251054015007348Currículo Lattesreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPspaActa Odontológica Venezolanainfo:eu-repo/semantics/openAccess2024-09-27T18:05:03Zoai:repositorio.unesp.br:11449/125862Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-27T18:05:03Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Evaluación del comportamiento biológico de tres cementos obturadores endodónticos en tejido subcutáneo de ratones |
title |
Evaluación del comportamiento biológico de tres cementos obturadores endodónticos en tejido subcutáneo de ratones |
spellingShingle |
Evaluación del comportamiento biológico de tres cementos obturadores endodónticos en tejido subcutáneo de ratones Moraes, Sergio Herrero Root canal obturation Toxicity Endodontic sealers Obturación del conducto radicular Biocompatibilidad Cementos endodónticos |
title_short |
Evaluación del comportamiento biológico de tres cementos obturadores endodónticos en tejido subcutáneo de ratones |
title_full |
Evaluación del comportamiento biológico de tres cementos obturadores endodónticos en tejido subcutáneo de ratones |
title_fullStr |
Evaluación del comportamiento biológico de tres cementos obturadores endodónticos en tejido subcutáneo de ratones |
title_full_unstemmed |
Evaluación del comportamiento biológico de tres cementos obturadores endodónticos en tejido subcutáneo de ratones |
title_sort |
Evaluación del comportamiento biológico de tres cementos obturadores endodónticos en tejido subcutáneo de ratones |
author |
Moraes, Sergio Herrero |
author_facet |
Moraes, Sergio Herrero Tanomaru Filho, Mario [UNESP] Chavez-Andrade, Gisele Moraima [UNESP] Silva, Guilherme Ferreira da [UNESP] Tanomaru, Juliane Mario Guerreiro [UNESP] |
author_role |
author |
author2 |
Tanomaru Filho, Mario [UNESP] Chavez-Andrade, Gisele Moraima [UNESP] Silva, Guilherme Ferreira da [UNESP] Tanomaru, Juliane Mario Guerreiro [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Federal do Paraná (UFPR) |
dc.contributor.author.fl_str_mv |
Moraes, Sergio Herrero Tanomaru Filho, Mario [UNESP] Chavez-Andrade, Gisele Moraima [UNESP] Silva, Guilherme Ferreira da [UNESP] Tanomaru, Juliane Mario Guerreiro [UNESP] |
dc.subject.por.fl_str_mv |
Root canal obturation Toxicity Endodontic sealers Obturación del conducto radicular Biocompatibilidad Cementos endodónticos |
topic |
Root canal obturation Toxicity Endodontic sealers Obturación del conducto radicular Biocompatibilidad Cementos endodónticos |
description |
The aim of this study was to evaluate the biological behavior of the root canal filling sealers: Endofill, Endomethasone and Sealer 26 when in contact with the subcutaneous connective tissue of rat. For the study one control and three experimental groups were used. A total of 15 animals were divided into 5 for each period: 7, 21, and 60 days. The obtained histological sections were processed and stained using the hematoxiline & eosine technique. The histological sections were subjective and comparatively analyzed using optic microscopy. The intensity of the inflammatory reaction and the level of fibrosis of the tissue were registered. The results were registered in scores and statistical analysis by KRUSKAL-WALLIS p<0,05 and MILLER methods. The statistical analysis revealed that in the period of 60 days, there was statistical significance to group II (Endofill) between group (control) and III (Endomethasone) with mononuclear cells into connective tissue. All materials promoted inflammatory reaction more intense at 7 and 21 days with the Endomethasone showing the best results. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012 2015-08-06T16:13:18Z 2015-08-06T16:13:18Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.actaodontologica.com/ediciones/2012/3/art8.asp Acta Odontológica Venezolana, v. 50, n. 3, p. 2-6, 2012. 0001-6365 http://hdl.handle.net/11449/125862 2665211298584751 1251054015007348 |
url |
http://www.actaodontologica.com/ediciones/2012/3/art8.asp http://hdl.handle.net/11449/125862 |
identifier_str_mv |
Acta Odontológica Venezolana, v. 50, n. 3, p. 2-6, 2012. 0001-6365 2665211298584751 1251054015007348 |
dc.language.iso.fl_str_mv |
spa |
language |
spa |
dc.relation.none.fl_str_mv |
Acta Odontológica Venezolana |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
2-6 |
dc.source.none.fl_str_mv |
Currículo Lattes reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
repositoriounesp@unesp.br |
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1813546526188765184 |