Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2014 |
| Outros Autores: | , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNESP |
| Texto Completo: | http://dx.doi.org/10.1590/1678-775720140209 http://hdl.handle.net/11449/126198 |
Resumo: | ObjectiveMineral Trioxide Aggregate (MTA) is composed of Portland Cement (PC) and bismuth oxide (BO). Replacing BO for niobium oxide (NbO) microparticles (Nbµ) or nanoparticles (Nbη) may improve radiopacity and bioactivity. The aim of this study was to evaluate the radiopacity and cytotoxicity of the materials: 1) PC; 2) White MTA; 3) PC+30% Nbµ; 4) PC+30% Nbη. Material and MethodFor the radiopacity test, specimens of the different materials were radiographed along an aluminum step-wedge. For cell culture assays, Saos-2 osteoblastic-cells (ATCC HTB-85) were used. Cell viability was evaluated through MTT assay, and bioactivity was assessed by alkaline phosphatase activity assay. ResultThe results demonstrated higher radiopacity for MTA, followed by Nbµ and Nbη, which had similar values. Cell culture analysis showed that PC and PC+NbO associations promoted greater cell viability than MTA. ConclusionIt was concluded that the combination of PC+NbO is a potential alternative for composition of MTA. |
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Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticlesSilicate cementNiobiumNanotechnologyObjectiveMineral Trioxide Aggregate (MTA) is composed of Portland Cement (PC) and bismuth oxide (BO). Replacing BO for niobium oxide (NbO) microparticles (Nbµ) or nanoparticles (Nbη) may improve radiopacity and bioactivity. The aim of this study was to evaluate the radiopacity and cytotoxicity of the materials: 1) PC; 2) White MTA; 3) PC+30% Nbµ; 4) PC+30% Nbη. Material and MethodFor the radiopacity test, specimens of the different materials were radiographed along an aluminum step-wedge. For cell culture assays, Saos-2 osteoblastic-cells (ATCC HTB-85) were used. Cell viability was evaluated through MTT assay, and bioactivity was assessed by alkaline phosphatase activity assay. ResultThe results demonstrated higher radiopacity for MTA, followed by Nbµ and Nbη, which had similar values. Cell culture analysis showed that PC and PC+NbO associations promoted greater cell viability than MTA. ConclusionIt was concluded that the combination of PC+NbO is a potential alternative for composition of MTA.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Univ. Estadual Paulista Araraquara Dental School Department of Restorative DentistryUniversity of São Paulo Institute of PhysicsFaculdade De Odontologia De Bauru - USPUniv. Estadual Paulista Araraquara Dental School Department of Restorative DentistryUniversity of São Paulo Institute of PhysicsMestieri, Leticia Boldrin [UNESP]Tanomaru-Filho, Mário [UNESP]Gomes-cornélio, Ana Livia [UNESP]Salles, Loise Pedrosa [UNESP]Bernardi, Maria Inês BassoGuerreiro-Tanomaru, Juliane Maria [UNESP]2015-08-06T16:14:48Z2015-08-06T16:14:48Z2014-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article554-559application/pdfhttp://dx.doi.org/10.1590/1678-775720140209Journal of Applied Oral Science. Faculdade De Odontologia De Bauru - USP, v. 22, n. 6, p. 554-559, 2014.1678-7757http://hdl.handle.net/11449/12619810.1590/1678-775720140209S1678-77572014000600554S1678-77572014000600554.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Applied Oral Science1.7090,645info:eu-repo/semantics/openAccess2023-10-01T06:04:21Zoai:repositorio.unesp.br:11449/126198Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-05-23T11:08:30.935370Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
| dc.title.none.fl_str_mv |
Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles |
| title |
Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles |
| spellingShingle |
Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles Mestieri, Leticia Boldrin [UNESP] Silicate cement Niobium Nanotechnology |
| title_short |
Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles |
| title_full |
Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles |
| title_fullStr |
Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles |
| title_full_unstemmed |
Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles |
| title_sort |
Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles |
| author |
Mestieri, Leticia Boldrin [UNESP] |
| author_facet |
Mestieri, Leticia Boldrin [UNESP] Tanomaru-Filho, Mário [UNESP] Gomes-cornélio, Ana Livia [UNESP] Salles, Loise Pedrosa [UNESP] Bernardi, Maria Inês Basso Guerreiro-Tanomaru, Juliane Maria [UNESP] |
| author_role |
author |
| author2 |
Tanomaru-Filho, Mário [UNESP] Gomes-cornélio, Ana Livia [UNESP] Salles, Loise Pedrosa [UNESP] Bernardi, Maria Inês Basso Guerreiro-Tanomaru, Juliane Maria [UNESP] |
| author2_role |
author author author author author |
| dc.contributor.none.fl_str_mv |
Univ. Estadual Paulista Araraquara Dental School Department of Restorative Dentistry University of São Paulo Institute of Physics |
| dc.contributor.author.fl_str_mv |
Mestieri, Leticia Boldrin [UNESP] Tanomaru-Filho, Mário [UNESP] Gomes-cornélio, Ana Livia [UNESP] Salles, Loise Pedrosa [UNESP] Bernardi, Maria Inês Basso Guerreiro-Tanomaru, Juliane Maria [UNESP] |
| dc.subject.por.fl_str_mv |
Silicate cement Niobium Nanotechnology |
| topic |
Silicate cement Niobium Nanotechnology |
| description |
ObjectiveMineral Trioxide Aggregate (MTA) is composed of Portland Cement (PC) and bismuth oxide (BO). Replacing BO for niobium oxide (NbO) microparticles (Nbµ) or nanoparticles (Nbη) may improve radiopacity and bioactivity. The aim of this study was to evaluate the radiopacity and cytotoxicity of the materials: 1) PC; 2) White MTA; 3) PC+30% Nbµ; 4) PC+30% Nbη. Material and MethodFor the radiopacity test, specimens of the different materials were radiographed along an aluminum step-wedge. For cell culture assays, Saos-2 osteoblastic-cells (ATCC HTB-85) were used. Cell viability was evaluated through MTT assay, and bioactivity was assessed by alkaline phosphatase activity assay. ResultThe results demonstrated higher radiopacity for MTA, followed by Nbµ and Nbη, which had similar values. Cell culture analysis showed that PC and PC+NbO associations promoted greater cell viability than MTA. ConclusionIt was concluded that the combination of PC+NbO is a potential alternative for composition of MTA. |
| publishDate |
2014 |
| dc.date.none.fl_str_mv |
2014-12-01 2015-08-06T16:14:48Z 2015-08-06T16:14:48Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1678-775720140209 Journal of Applied Oral Science. Faculdade De Odontologia De Bauru - USP, v. 22, n. 6, p. 554-559, 2014. 1678-7757 http://hdl.handle.net/11449/126198 10.1590/1678-775720140209 S1678-77572014000600554 S1678-77572014000600554.pdf |
| url |
http://dx.doi.org/10.1590/1678-775720140209 http://hdl.handle.net/11449/126198 |
| identifier_str_mv |
Journal of Applied Oral Science. Faculdade De Odontologia De Bauru - USP, v. 22, n. 6, p. 554-559, 2014. 1678-7757 10.1590/1678-775720140209 S1678-77572014000600554 S1678-77572014000600554.pdf |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Journal of Applied Oral Science 1.709 0,645 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
554-559 application/pdf |
| dc.publisher.none.fl_str_mv |
Faculdade De Odontologia De Bauru - USP |
| publisher.none.fl_str_mv |
Faculdade De Odontologia De Bauru - USP |
| dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
| instname_str |
Universidade Estadual Paulista (UNESP) |
| instacron_str |
UNESP |
| institution |
UNESP |
| reponame_str |
Repositório Institucional da UNESP |
| collection |
Repositório Institucional da UNESP |
| repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
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1803045777479565312 |