Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles

Detalhes bibliográficos
Autor(a) principal: MESTIERI,Leticia Boldrin
Data de Publicação: 2014
Outros Autores: TANOMARU-FILHO,Mário, GOMES-CORNÉLIO,Ana Livia, SALLES,Loise Pedrosa, BERNARDI,Maria Inês Basso, GUERREIRO-TANOMARU,Juliane Maria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572014000600554
Resumo: Objective Mineral Trioxide Aggregate (MTA) is composed of Portland Cement (PC) and bismuth oxide (BO). Replacing BO for niobium oxide (NbO) microparticles (Nbµ) or nanoparticles (Nbη) may improve radiopacity and bioactivity. The aim of this study was to evaluate the radiopacity and cytotoxicity of the materials: 1) PC; 2) White MTA; 3) PC+30% Nbµ; 4) PC+30% Nbη. Material and Methods For the radiopacity test, specimens of the different materials were radiographed along an aluminum step-wedge. For cell culture assays, Saos-2 osteoblastic-cells (ATCC HTB-85) were used. Cell viability was evaluated through MTT assay, and bioactivity was assessed by alkaline phosphatase activity assay. Results The results demonstrated higher radiopacity for MTA, followed by Nbµ and Nbη, which had similar values. Cell culture analysis showed that PC and PC+NbO associations promoted greater cell viability than MTA. Conclusions It was concluded that the combination of PC+NbO is a potential alternative for composition of MTA.
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spelling Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticlesSilicate cementNiobiumNanotechnology Objective Mineral Trioxide Aggregate (MTA) is composed of Portland Cement (PC) and bismuth oxide (BO). Replacing BO for niobium oxide (NbO) microparticles (Nbµ) or nanoparticles (Nbη) may improve radiopacity and bioactivity. The aim of this study was to evaluate the radiopacity and cytotoxicity of the materials: 1) PC; 2) White MTA; 3) PC+30% Nbµ; 4) PC+30% Nbη. Material and Methods For the radiopacity test, specimens of the different materials were radiographed along an aluminum step-wedge. For cell culture assays, Saos-2 osteoblastic-cells (ATCC HTB-85) were used. Cell viability was evaluated through MTT assay, and bioactivity was assessed by alkaline phosphatase activity assay. Results The results demonstrated higher radiopacity for MTA, followed by Nbµ and Nbη, which had similar values. Cell culture analysis showed that PC and PC+NbO associations promoted greater cell viability than MTA. Conclusions It was concluded that the combination of PC+NbO is a potential alternative for composition of MTA. Faculdade De Odontologia De Bauru - USP2014-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572014000600554Journal of Applied Oral Science v.22 n.6 2014reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USP10.1590/1678-775720140209info:eu-repo/semantics/openAccessMESTIERI,Leticia BoldrinTANOMARU-FILHO,MárioGOMES-CORNÉLIO,Ana LiviaSALLES,Loise PedrosaBERNARDI,Maria Inês BassoGUERREIRO-TANOMARU,Juliane Mariaeng2014-12-18T00:00:00Zoai:scielo:S1678-77572014000600554Revistahttp://www.scielo.br/jaosPUBhttps://old.scielo.br/oai/scielo-oai.php||jaos@usp.br1678-77651678-7757opendoar:2014-12-18T00:00Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles
title Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles
spellingShingle Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles
MESTIERI,Leticia Boldrin
Silicate cement
Niobium
Nanotechnology
title_short Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles
title_full Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles
title_fullStr Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles
title_full_unstemmed Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles
title_sort Radiopacity and cytotoxicity of Portland cement associated with niobium oxide micro and nanoparticles
author MESTIERI,Leticia Boldrin
author_facet MESTIERI,Leticia Boldrin
TANOMARU-FILHO,Mário
GOMES-CORNÉLIO,Ana Livia
SALLES,Loise Pedrosa
BERNARDI,Maria Inês Basso
GUERREIRO-TANOMARU,Juliane Maria
author_role author
author2 TANOMARU-FILHO,Mário
GOMES-CORNÉLIO,Ana Livia
SALLES,Loise Pedrosa
BERNARDI,Maria Inês Basso
GUERREIRO-TANOMARU,Juliane Maria
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv MESTIERI,Leticia Boldrin
TANOMARU-FILHO,Mário
GOMES-CORNÉLIO,Ana Livia
SALLES,Loise Pedrosa
BERNARDI,Maria Inês Basso
GUERREIRO-TANOMARU,Juliane Maria
dc.subject.por.fl_str_mv Silicate cement
Niobium
Nanotechnology
topic Silicate cement
Niobium
Nanotechnology
description Objective Mineral Trioxide Aggregate (MTA) is composed of Portland Cement (PC) and bismuth oxide (BO). Replacing BO for niobium oxide (NbO) microparticles (Nbµ) or nanoparticles (Nbη) may improve radiopacity and bioactivity. The aim of this study was to evaluate the radiopacity and cytotoxicity of the materials: 1) PC; 2) White MTA; 3) PC+30% Nbµ; 4) PC+30% Nbη. Material and Methods For the radiopacity test, specimens of the different materials were radiographed along an aluminum step-wedge. For cell culture assays, Saos-2 osteoblastic-cells (ATCC HTB-85) were used. Cell viability was evaluated through MTT assay, and bioactivity was assessed by alkaline phosphatase activity assay. Results The results demonstrated higher radiopacity for MTA, followed by Nbµ and Nbη, which had similar values. Cell culture analysis showed that PC and PC+NbO associations promoted greater cell viability than MTA. Conclusions It was concluded that the combination of PC+NbO is a potential alternative for composition of MTA.
publishDate 2014
dc.date.none.fl_str_mv 2014-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572014000600554
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572014000600554
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-775720140209
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade De Odontologia De Bauru - USP
publisher.none.fl_str_mv Faculdade De Odontologia De Bauru - USP
dc.source.none.fl_str_mv Journal of Applied Oral Science v.22 n.6 2014
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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