Center of pressure responses to unpredictable external perturbations indicate low accuracy in predicting fall risk in people with Parkinson’s disease
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1111/ejn.15143 http://hdl.handle.net/11449/208435 |
Resumo: | Falls are associated with impairment in postural control in people with Parkinson's disease (PwPD). We aimed to predict the fall risk through models combining postural responses with clinical and cognitive measures. Also, we compared the center of pressure (CoP) between PwPD fallers and non-fallers after unpredictable external perturbations. We expected that CoP parameters combined with clinical and cognitive measures would predict fall risk. Seventy-five individuals participated in the study. CoP parameters were measured during postural responses through five trials with unpredictable translations of the support-surface in posterior direction. Range and peak of CoP were analyzed in two periods: early and late responses. Time to peak (negative peak) and recovery time were analyzed regardless of the periods. Models included the CoP parameters in early (model 1), late responses (model 2), and temporal parameters (model 3). Clinical and cognitive measures were entered into all models. Twenty-nine participants fell at least once, and 46 PwPD did not fall during 12 months following the postural assessment. Range of CoP in late responses was associated with fall risk (p =.046). However, although statistically non-significant, this parameter indicated low accuracy in predicting fall risk (area under the curve = 0.58). Fallers presented a higher range of CoP in early responses than non-fallers (p =.033). In conclusion, although an association was observed between fall risk and range of CoP in late responses, this parameter indicated low accuracy in predicting fall risk in PwPD. Also, fallers demonstrate worse postural control during early responses after external perturbations than non-fallers, measured by CoP parameters. |
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Repositório Institucional da UNESP |
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Center of pressure responses to unpredictable external perturbations indicate low accuracy in predicting fall risk in people with Parkinson’s diseasecenter of pressurefalls predictionmovement disorderspostural controlsupport-surface translationFalls are associated with impairment in postural control in people with Parkinson's disease (PwPD). We aimed to predict the fall risk through models combining postural responses with clinical and cognitive measures. Also, we compared the center of pressure (CoP) between PwPD fallers and non-fallers after unpredictable external perturbations. We expected that CoP parameters combined with clinical and cognitive measures would predict fall risk. Seventy-five individuals participated in the study. CoP parameters were measured during postural responses through five trials with unpredictable translations of the support-surface in posterior direction. Range and peak of CoP were analyzed in two periods: early and late responses. Time to peak (negative peak) and recovery time were analyzed regardless of the periods. Models included the CoP parameters in early (model 1), late responses (model 2), and temporal parameters (model 3). Clinical and cognitive measures were entered into all models. Twenty-nine participants fell at least once, and 46 PwPD did not fall during 12 months following the postural assessment. Range of CoP in late responses was associated with fall risk (p =.046). However, although statistically non-significant, this parameter indicated low accuracy in predicting fall risk (area under the curve = 0.58). Fallers presented a higher range of CoP in early responses than non-fallers (p =.033). In conclusion, although an association was observed between fall risk and range of CoP in late responses, this parameter indicated low accuracy in predicting fall risk in PwPD. Also, fallers demonstrate worse postural control during early responses after external perturbations than non-fallers, measured by CoP parameters.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Institute of Biosciences Posture and Gait Studies Laboratory (LEPLO) São Paulo State University (Unesp)Graduate Program in Movement Sciences São Paulo State University (Unesp)Center for Human Movement Sciences University Medical Center Groningen University of GroningenDepartment of Neurology Oregon Health & Science UniversityInstitute of Biosciences Posture and Gait Studies Laboratory (LEPLO) São Paulo State University (Unesp)Graduate Program in Movement Sciences São Paulo State University (Unesp)FAPESP: 2016/00503-0FAPESP: 2019/01203-9CNPq: 309045/2017-7CNPq: 429549/2018-0Universidade Estadual Paulista (Unesp)University of GroningenOregon Health & Science UniversityMoraca, Gabriel Antonio Gazziero [UNESP]Beretta, Victor Spiandor [UNESP]dos Santos, Paulo Cezar Rocha [UNESP]Nóbrega-Sousa, Priscila [UNESP]Orcioli-Silva, Diego [UNESP]Vitório, Rodrigo [UNESP]Gobbi, Lilian Teresa Bucken [UNESP]2021-06-25T11:12:05Z2021-06-25T11:12:05Z2021-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2901-2911http://dx.doi.org/10.1111/ejn.15143European Journal of Neuroscience, v. 53, n. 8, p. 2901-2911, 2021.1460-95680953-816Xhttp://hdl.handle.net/11449/20843510.1111/ejn.151432-s2.0-85101260020Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengEuropean Journal of Neuroscienceinfo:eu-repo/semantics/openAccess2021-10-23T19:02:10Zoai:repositorio.unesp.br:11449/208435Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T23:51:51.801539Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Center of pressure responses to unpredictable external perturbations indicate low accuracy in predicting fall risk in people with Parkinson’s disease |
title |
Center of pressure responses to unpredictable external perturbations indicate low accuracy in predicting fall risk in people with Parkinson’s disease |
spellingShingle |
Center of pressure responses to unpredictable external perturbations indicate low accuracy in predicting fall risk in people with Parkinson’s disease Moraca, Gabriel Antonio Gazziero [UNESP] center of pressure falls prediction movement disorders postural control support-surface translation |
title_short |
Center of pressure responses to unpredictable external perturbations indicate low accuracy in predicting fall risk in people with Parkinson’s disease |
title_full |
Center of pressure responses to unpredictable external perturbations indicate low accuracy in predicting fall risk in people with Parkinson’s disease |
title_fullStr |
Center of pressure responses to unpredictable external perturbations indicate low accuracy in predicting fall risk in people with Parkinson’s disease |
title_full_unstemmed |
Center of pressure responses to unpredictable external perturbations indicate low accuracy in predicting fall risk in people with Parkinson’s disease |
title_sort |
Center of pressure responses to unpredictable external perturbations indicate low accuracy in predicting fall risk in people with Parkinson’s disease |
author |
Moraca, Gabriel Antonio Gazziero [UNESP] |
author_facet |
Moraca, Gabriel Antonio Gazziero [UNESP] Beretta, Victor Spiandor [UNESP] dos Santos, Paulo Cezar Rocha [UNESP] Nóbrega-Sousa, Priscila [UNESP] Orcioli-Silva, Diego [UNESP] Vitório, Rodrigo [UNESP] Gobbi, Lilian Teresa Bucken [UNESP] |
author_role |
author |
author2 |
Beretta, Victor Spiandor [UNESP] dos Santos, Paulo Cezar Rocha [UNESP] Nóbrega-Sousa, Priscila [UNESP] Orcioli-Silva, Diego [UNESP] Vitório, Rodrigo [UNESP] Gobbi, Lilian Teresa Bucken [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) University of Groningen Oregon Health & Science University |
dc.contributor.author.fl_str_mv |
Moraca, Gabriel Antonio Gazziero [UNESP] Beretta, Victor Spiandor [UNESP] dos Santos, Paulo Cezar Rocha [UNESP] Nóbrega-Sousa, Priscila [UNESP] Orcioli-Silva, Diego [UNESP] Vitório, Rodrigo [UNESP] Gobbi, Lilian Teresa Bucken [UNESP] |
dc.subject.por.fl_str_mv |
center of pressure falls prediction movement disorders postural control support-surface translation |
topic |
center of pressure falls prediction movement disorders postural control support-surface translation |
description |
Falls are associated with impairment in postural control in people with Parkinson's disease (PwPD). We aimed to predict the fall risk through models combining postural responses with clinical and cognitive measures. Also, we compared the center of pressure (CoP) between PwPD fallers and non-fallers after unpredictable external perturbations. We expected that CoP parameters combined with clinical and cognitive measures would predict fall risk. Seventy-five individuals participated in the study. CoP parameters were measured during postural responses through five trials with unpredictable translations of the support-surface in posterior direction. Range and peak of CoP were analyzed in two periods: early and late responses. Time to peak (negative peak) and recovery time were analyzed regardless of the periods. Models included the CoP parameters in early (model 1), late responses (model 2), and temporal parameters (model 3). Clinical and cognitive measures were entered into all models. Twenty-nine participants fell at least once, and 46 PwPD did not fall during 12 months following the postural assessment. Range of CoP in late responses was associated with fall risk (p =.046). However, although statistically non-significant, this parameter indicated low accuracy in predicting fall risk (area under the curve = 0.58). Fallers presented a higher range of CoP in early responses than non-fallers (p =.033). In conclusion, although an association was observed between fall risk and range of CoP in late responses, this parameter indicated low accuracy in predicting fall risk in PwPD. Also, fallers demonstrate worse postural control during early responses after external perturbations than non-fallers, measured by CoP parameters. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T11:12:05Z 2021-06-25T11:12:05Z 2021-04-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1111/ejn.15143 European Journal of Neuroscience, v. 53, n. 8, p. 2901-2911, 2021. 1460-9568 0953-816X http://hdl.handle.net/11449/208435 10.1111/ejn.15143 2-s2.0-85101260020 |
url |
http://dx.doi.org/10.1111/ejn.15143 http://hdl.handle.net/11449/208435 |
identifier_str_mv |
European Journal of Neuroscience, v. 53, n. 8, p. 2901-2911, 2021. 1460-9568 0953-816X 10.1111/ejn.15143 2-s2.0-85101260020 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
European Journal of Neuroscience |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
2901-2911 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1808129559428595712 |