Head and neck squamous cell carcinoma in young patients: A 26-year clinicopathologic retrospective study in a Brazilian specialized center
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.4317/medoral.23460 http://hdl.handle.net/11449/200307 |
Resumo: | Background: To describe the clinicopathologic profile of young patients with head and neck squamous cell carcinoma (HNSCC) and compare to middle-aged and elderly adults. Material and Methods: Patients' individual records were reviewed for clinicopathologic data. Eighty-nine patients with age 18-45 years old met the inclusion criteria of the study. Two additional groups of middle-aged (n=89) and old (n=89) adults were set to comparative analysis. Results: Young patients represented 11.9% of all patients diagnosed with HNSCC. Women were more affected by HNSCC in the young and elder groups (p= 0.04), and young patients were more prone to be non-smokers (p= 0.01) and have lymph node metastasis at the time of diagnosis (p=0.04). In the young group, patients diagnosed with the disease in advanced stages were more prone to have a positive familial history of cancer (p= 0.04), a positive status of alcohol consumption (p= 0.03), and to be heavy drinkers (p= 0.01). Survival was not different for the young group in comparison to the other groups. Conclusions: HNSCC in young patients had a different profile when compared to older patients, especially regarding sex and exposure to the classic risk factors for this disease. The survival of the young group is similar to the older groups and advanced clinical stage is predictor of worse survival. |
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Head and neck squamous cell carcinoma in young patients: A 26-year clinicopathologic retrospective study in a Brazilian specialized centerEpidemiologyMouth neoplasmsYoung adultBackground: To describe the clinicopathologic profile of young patients with head and neck squamous cell carcinoma (HNSCC) and compare to middle-aged and elderly adults. Material and Methods: Patients' individual records were reviewed for clinicopathologic data. Eighty-nine patients with age 18-45 years old met the inclusion criteria of the study. Two additional groups of middle-aged (n=89) and old (n=89) adults were set to comparative analysis. Results: Young patients represented 11.9% of all patients diagnosed with HNSCC. Women were more affected by HNSCC in the young and elder groups (p= 0.04), and young patients were more prone to be non-smokers (p= 0.01) and have lymph node metastasis at the time of diagnosis (p=0.04). In the young group, patients diagnosed with the disease in advanced stages were more prone to have a positive familial history of cancer (p= 0.04), a positive status of alcohol consumption (p= 0.03), and to be heavy drinkers (p= 0.01). Survival was not different for the young group in comparison to the other groups. Conclusions: HNSCC in young patients had a different profile when compared to older patients, especially regarding sex and exposure to the classic risk factors for this disease. The survival of the young group is similar to the older groups and advanced clinical stage is predictor of worse survival.Oral Oncology Center Araçatuba Dental School São Paulo State University - UNESPOral Oncology Center Araçatuba Dental School São Paulo State University - UNESPUniversidade Estadual Paulista (Unesp)Tomo, Saygo [UNESP]Neto, Sebastião Conrado [UNESP]Collado, Francisco Urbano [UNESP]Sundefeld, Maria Lúcia Marçal Mazza [UNESP]Bernabé, Daniel Galera [UNESP]Biasoli, Éder Ricardo [UNESP]Miyahara, Glauco Issamu [UNESP]2020-12-12T02:03:09Z2020-12-12T02:03:09Z2020-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlee410-e415http://dx.doi.org/10.4317/medoral.23460Medicina Oral Patologia Oral y Cirugia Bucal, v. 25, n. 3, p. e410-e415, 2020.1698-69461698-4447http://hdl.handle.net/11449/20030710.4317/medoral.234602-s2.0-85083544714Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMedicina Oral Patologia Oral y Cirugia Bucalinfo:eu-repo/semantics/openAccess2024-04-11T20:16:33Zoai:repositorio.unesp.br:11449/200307Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T20:31:34.612157Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Head and neck squamous cell carcinoma in young patients: A 26-year clinicopathologic retrospective study in a Brazilian specialized center |
title |
Head and neck squamous cell carcinoma in young patients: A 26-year clinicopathologic retrospective study in a Brazilian specialized center |
spellingShingle |
Head and neck squamous cell carcinoma in young patients: A 26-year clinicopathologic retrospective study in a Brazilian specialized center Tomo, Saygo [UNESP] Epidemiology Mouth neoplasms Young adult |
title_short |
Head and neck squamous cell carcinoma in young patients: A 26-year clinicopathologic retrospective study in a Brazilian specialized center |
title_full |
Head and neck squamous cell carcinoma in young patients: A 26-year clinicopathologic retrospective study in a Brazilian specialized center |
title_fullStr |
Head and neck squamous cell carcinoma in young patients: A 26-year clinicopathologic retrospective study in a Brazilian specialized center |
title_full_unstemmed |
Head and neck squamous cell carcinoma in young patients: A 26-year clinicopathologic retrospective study in a Brazilian specialized center |
title_sort |
Head and neck squamous cell carcinoma in young patients: A 26-year clinicopathologic retrospective study in a Brazilian specialized center |
author |
Tomo, Saygo [UNESP] |
author_facet |
Tomo, Saygo [UNESP] Neto, Sebastião Conrado [UNESP] Collado, Francisco Urbano [UNESP] Sundefeld, Maria Lúcia Marçal Mazza [UNESP] Bernabé, Daniel Galera [UNESP] Biasoli, Éder Ricardo [UNESP] Miyahara, Glauco Issamu [UNESP] |
author_role |
author |
author2 |
Neto, Sebastião Conrado [UNESP] Collado, Francisco Urbano [UNESP] Sundefeld, Maria Lúcia Marçal Mazza [UNESP] Bernabé, Daniel Galera [UNESP] Biasoli, Éder Ricardo [UNESP] Miyahara, Glauco Issamu [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Tomo, Saygo [UNESP] Neto, Sebastião Conrado [UNESP] Collado, Francisco Urbano [UNESP] Sundefeld, Maria Lúcia Marçal Mazza [UNESP] Bernabé, Daniel Galera [UNESP] Biasoli, Éder Ricardo [UNESP] Miyahara, Glauco Issamu [UNESP] |
dc.subject.por.fl_str_mv |
Epidemiology Mouth neoplasms Young adult |
topic |
Epidemiology Mouth neoplasms Young adult |
description |
Background: To describe the clinicopathologic profile of young patients with head and neck squamous cell carcinoma (HNSCC) and compare to middle-aged and elderly adults. Material and Methods: Patients' individual records were reviewed for clinicopathologic data. Eighty-nine patients with age 18-45 years old met the inclusion criteria of the study. Two additional groups of middle-aged (n=89) and old (n=89) adults were set to comparative analysis. Results: Young patients represented 11.9% of all patients diagnosed with HNSCC. Women were more affected by HNSCC in the young and elder groups (p= 0.04), and young patients were more prone to be non-smokers (p= 0.01) and have lymph node metastasis at the time of diagnosis (p=0.04). In the young group, patients diagnosed with the disease in advanced stages were more prone to have a positive familial history of cancer (p= 0.04), a positive status of alcohol consumption (p= 0.03), and to be heavy drinkers (p= 0.01). Survival was not different for the young group in comparison to the other groups. Conclusions: HNSCC in young patients had a different profile when compared to older patients, especially regarding sex and exposure to the classic risk factors for this disease. The survival of the young group is similar to the older groups and advanced clinical stage is predictor of worse survival. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T02:03:09Z 2020-12-12T02:03:09Z 2020-05-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.4317/medoral.23460 Medicina Oral Patologia Oral y Cirugia Bucal, v. 25, n. 3, p. e410-e415, 2020. 1698-6946 1698-4447 http://hdl.handle.net/11449/200307 10.4317/medoral.23460 2-s2.0-85083544714 |
url |
http://dx.doi.org/10.4317/medoral.23460 http://hdl.handle.net/11449/200307 |
identifier_str_mv |
Medicina Oral Patologia Oral y Cirugia Bucal, v. 25, n. 3, p. e410-e415, 2020. 1698-6946 1698-4447 10.4317/medoral.23460 2-s2.0-85083544714 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Medicina Oral Patologia Oral y Cirugia Bucal |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
e410-e415 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1808129214798364672 |