A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay

Detalhes bibliográficos
Autor(a) principal: OLIVEIRA,Maria Laura Cosetti
Data de Publicação: 2015
Outros Autores: WAGNER,Vivian Petersen, SANT'ANA FILHO,Manoel, CARRARD,Vinicius Coelho, HUGO,Fernando Neves, MARTINS,Manoela Domingues
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Oral Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242015000100270
Resumo: The aim of this study was to evaluate the demographic, clinical, and therapeutic characteristics and predictive factors of poor prognosis in patients with primary oral squamous cell carcinoma (OSCC) in Uruguay. Medical records of patients with the diagnosis of primary OSCC treated between 2000 and 2010 in Uruguayan public hospitals were selected. Data on demographic characteristics, risk factors, clinical features, treatment, and outcome were collected. Associations of independent variables with outcomes were assessed using Pearson chi-squared and Fisher's tests. Of 200 patients with OSCC, 79.4% were men (3.8:1 male:female ratio), with a mean age of 60.75 ± 11.26 years. Tobacco and alcohol consumption were reported by 85.3% and 63.5% of patients, respectively. The most commonly affected location was the tongue (42.5%), with lesions exhibiting ulcerous aspects in 87.9% of cases and pain at the time of diagnosis in 70.4% of cases. One hundred sixty-one (82.1%) patients had advanced-stage (III/IV) OSCC. Surgery was the most common treatment option, and the overall 5-year survival rate was 58.5%. Univariate analysis showed that the predictors of poor prognosis were clinical aspect, size, regional metastasis, clinical stage, and treatment. In Uruguay, OSCC is diagnosed late, which is associated with a low survival rate. Educational and preventive measures and investment to improve early diagnosis should be undertaken.
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spelling A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in UruguayMouth NeoplasmsEpidemiologyPrognosisDelayed DiagnosisThe aim of this study was to evaluate the demographic, clinical, and therapeutic characteristics and predictive factors of poor prognosis in patients with primary oral squamous cell carcinoma (OSCC) in Uruguay. Medical records of patients with the diagnosis of primary OSCC treated between 2000 and 2010 in Uruguayan public hospitals were selected. Data on demographic characteristics, risk factors, clinical features, treatment, and outcome were collected. Associations of independent variables with outcomes were assessed using Pearson chi-squared and Fisher's tests. Of 200 patients with OSCC, 79.4% were men (3.8:1 male:female ratio), with a mean age of 60.75 ± 11.26 years. Tobacco and alcohol consumption were reported by 85.3% and 63.5% of patients, respectively. The most commonly affected location was the tongue (42.5%), with lesions exhibiting ulcerous aspects in 87.9% of cases and pain at the time of diagnosis in 70.4% of cases. One hundred sixty-one (82.1%) patients had advanced-stage (III/IV) OSCC. Surgery was the most common treatment option, and the overall 5-year survival rate was 58.5%. Univariate analysis showed that the predictors of poor prognosis were clinical aspect, size, regional metastasis, clinical stage, and treatment. In Uruguay, OSCC is diagnosed late, which is associated with a low survival rate. Educational and preventive measures and investment to improve early diagnosis should be undertaken.Sociedade Brasileira de Pesquisa Odontológica - SBPqO2015-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242015000100270Brazilian Oral Research v.29 n.1 2015reponame:Brazilian Oral Researchinstname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)instacron:SBPQO10.1590/1807-3107BOR-2015.vol29.0075info:eu-repo/semantics/openAccessOLIVEIRA,Maria Laura CosettiWAGNER,Vivian PetersenSANT'ANA FILHO,ManoelCARRARD,Vinicius CoelhoHUGO,Fernando NevesMARTINS,Manoela Domingueseng2018-09-17T00:00:00Zoai:scielo:S1806-83242015000100270Revistahttps://www.scielo.br/j/bor/https://old.scielo.br/oai/scielo-oai.phppob@edu.usp.br||bor@sbpqo.org.br1807-31071806-8324opendoar:2018-09-17T00:00Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)false
dc.title.none.fl_str_mv A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay
title A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay
spellingShingle A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay
OLIVEIRA,Maria Laura Cosetti
Mouth Neoplasms
Epidemiology
Prognosis
Delayed Diagnosis
title_short A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay
title_full A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay
title_fullStr A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay
title_full_unstemmed A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay
title_sort A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay
author OLIVEIRA,Maria Laura Cosetti
author_facet OLIVEIRA,Maria Laura Cosetti
WAGNER,Vivian Petersen
SANT'ANA FILHO,Manoel
CARRARD,Vinicius Coelho
HUGO,Fernando Neves
MARTINS,Manoela Domingues
author_role author
author2 WAGNER,Vivian Petersen
SANT'ANA FILHO,Manoel
CARRARD,Vinicius Coelho
HUGO,Fernando Neves
MARTINS,Manoela Domingues
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv OLIVEIRA,Maria Laura Cosetti
WAGNER,Vivian Petersen
SANT'ANA FILHO,Manoel
CARRARD,Vinicius Coelho
HUGO,Fernando Neves
MARTINS,Manoela Domingues
dc.subject.por.fl_str_mv Mouth Neoplasms
Epidemiology
Prognosis
Delayed Diagnosis
topic Mouth Neoplasms
Epidemiology
Prognosis
Delayed Diagnosis
description The aim of this study was to evaluate the demographic, clinical, and therapeutic characteristics and predictive factors of poor prognosis in patients with primary oral squamous cell carcinoma (OSCC) in Uruguay. Medical records of patients with the diagnosis of primary OSCC treated between 2000 and 2010 in Uruguayan public hospitals were selected. Data on demographic characteristics, risk factors, clinical features, treatment, and outcome were collected. Associations of independent variables with outcomes were assessed using Pearson chi-squared and Fisher's tests. Of 200 patients with OSCC, 79.4% were men (3.8:1 male:female ratio), with a mean age of 60.75 ± 11.26 years. Tobacco and alcohol consumption were reported by 85.3% and 63.5% of patients, respectively. The most commonly affected location was the tongue (42.5%), with lesions exhibiting ulcerous aspects in 87.9% of cases and pain at the time of diagnosis in 70.4% of cases. One hundred sixty-one (82.1%) patients had advanced-stage (III/IV) OSCC. Surgery was the most common treatment option, and the overall 5-year survival rate was 58.5%. Univariate analysis showed that the predictors of poor prognosis were clinical aspect, size, regional metastasis, clinical stage, and treatment. In Uruguay, OSCC is diagnosed late, which is associated with a low survival rate. Educational and preventive measures and investment to improve early diagnosis should be undertaken.
publishDate 2015
dc.date.none.fl_str_mv 2015-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242015000100270
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242015000100270
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1807-3107BOR-2015.vol29.0075
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
publisher.none.fl_str_mv Sociedade Brasileira de Pesquisa Odontológica - SBPqO
dc.source.none.fl_str_mv Brazilian Oral Research v.29 n.1 2015
reponame:Brazilian Oral Research
instname:Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO
instname_str Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron_str SBPQO
institution SBPQO
reponame_str Brazilian Oral Research
collection Brazilian Oral Research
repository.name.fl_str_mv Brazilian Oral Research - Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
repository.mail.fl_str_mv pob@edu.usp.br||bor@sbpqo.org.br
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