Prospective study for the development of emulsion systems containing natural oil products

Detalhes bibliográficos
Autor(a) principal: Xavier, F. H.
Data de Publicação: 2012
Outros Autores: Silva, K. G.H., Farias, I. E.G., Morais, A. R.V., Alencar, E. N., Araújo, I. B., Oliveira, A. G. [UNESP], Egito, E. S.T.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1016/s1773-2247(12)50061-4
http://hdl.handle.net/11449/219833
Resumo: Copaiba oil, when used as anti-inflammatory and anti-infective agent, presents two major problems: i) low absorption and bioavailability and ii) an unpleasant taste. Once an appropriate emulsion was achieved, the samples were prepared using different surfactant binary mixtures to obtain a range of HLB values between 45 and 16.5. The HLB value of copaiba oil was 14.8; this system has been stable for more than one year, and the pseudo-ternary diagrams were useful to describe the component proportions. These results indicated that the copaiba oil emulsion might be a promising vehicle for topical delivery of drugs and active cosmetic ingredients.
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spelling Prospective study for the development of emulsion systems containing natural oil productsCopaiba oilEmulsionHydrophilic-lipophilic balancePseudo-ternary phase diagramStability analysisCopaiba oil, when used as anti-inflammatory and anti-infective agent, presents two major problems: i) low absorption and bioavailability and ii) an unpleasant taste. Once an appropriate emulsion was achieved, the samples were prepared using different surfactant binary mixtures to obtain a range of HLB values between 45 and 16.5. The HLB value of copaiba oil was 14.8; this system has been stable for more than one year, and the pseudo-ternary diagrams were useful to describe the component proportions. These results indicated that the copaiba oil emulsion might be a promising vehicle for topical delivery of drugs and active cosmetic ingredients.Universidade Federal do Rio Grande do Norte (UFRN) Centro de Ciências da Saúde (CCS) Programa de Pós-Graduação em Ciências da Saúde (PPGCSa), Av. Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, 59010-180, Natal-RNUFRN Departamento de Farmácia LaSiD, Av. Gal. Gustavo Cordeiro de Farias, S/N, Petrópolis, 59010-180, Natal-RNUNESP Faculdade de Ciências Farmacêuticas Grupo de Sistemas Biomiméticos, Rodovia Araraquara-Jau, km 01, 14801-902, Araraquara-SPUNESP Faculdade de Ciências Farmacêuticas Grupo de Sistemas Biomiméticos, Rodovia Araraquara-Jau, km 01, 14801-902, Araraquara-SPPrograma de Pós-Graduação em Ciências da Saúde (PPGCSa)LaSiDUniversidade Estadual Paulista (UNESP)Xavier, F. H.Silva, K. G.H.Farias, I. E.G.Morais, A. R.V.Alencar, E. N.Araújo, I. B.Oliveira, A. G. [UNESP]Egito, E. S.T.2022-04-28T18:58:01Z2022-04-28T18:58:01Z2012-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article367-372http://dx.doi.org/10.1016/s1773-2247(12)50061-4Journal of Drug Delivery Science and Technology, v. 22, n. 4, p. 367-372, 2012.1773-2247http://hdl.handle.net/11449/21983310.1016/s1773-2247(12)50061-42-s2.0-84865835486Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Drug Delivery Science and Technologyinfo:eu-repo/semantics/openAccess2022-04-28T18:58:01Zoai:repositorio.unesp.br:11449/219833Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:45:35.599877Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Prospective study for the development of emulsion systems containing natural oil products
title Prospective study for the development of emulsion systems containing natural oil products
spellingShingle Prospective study for the development of emulsion systems containing natural oil products
Xavier, F. H.
Copaiba oil
Emulsion
Hydrophilic-lipophilic balance
Pseudo-ternary phase diagram
Stability analysis
title_short Prospective study for the development of emulsion systems containing natural oil products
title_full Prospective study for the development of emulsion systems containing natural oil products
title_fullStr Prospective study for the development of emulsion systems containing natural oil products
title_full_unstemmed Prospective study for the development of emulsion systems containing natural oil products
title_sort Prospective study for the development of emulsion systems containing natural oil products
author Xavier, F. H.
author_facet Xavier, F. H.
Silva, K. G.H.
Farias, I. E.G.
Morais, A. R.V.
Alencar, E. N.
Araújo, I. B.
Oliveira, A. G. [UNESP]
Egito, E. S.T.
author_role author
author2 Silva, K. G.H.
Farias, I. E.G.
Morais, A. R.V.
Alencar, E. N.
Araújo, I. B.
Oliveira, A. G. [UNESP]
Egito, E. S.T.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Programa de Pós-Graduação em Ciências da Saúde (PPGCSa)
LaSiD
Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Xavier, F. H.
Silva, K. G.H.
Farias, I. E.G.
Morais, A. R.V.
Alencar, E. N.
Araújo, I. B.
Oliveira, A. G. [UNESP]
Egito, E. S.T.
dc.subject.por.fl_str_mv Copaiba oil
Emulsion
Hydrophilic-lipophilic balance
Pseudo-ternary phase diagram
Stability analysis
topic Copaiba oil
Emulsion
Hydrophilic-lipophilic balance
Pseudo-ternary phase diagram
Stability analysis
description Copaiba oil, when used as anti-inflammatory and anti-infective agent, presents two major problems: i) low absorption and bioavailability and ii) an unpleasant taste. Once an appropriate emulsion was achieved, the samples were prepared using different surfactant binary mixtures to obtain a range of HLB values between 45 and 16.5. The HLB value of copaiba oil was 14.8; this system has been stable for more than one year, and the pseudo-ternary diagrams were useful to describe the component proportions. These results indicated that the copaiba oil emulsion might be a promising vehicle for topical delivery of drugs and active cosmetic ingredients.
publishDate 2012
dc.date.none.fl_str_mv 2012-01-01
2022-04-28T18:58:01Z
2022-04-28T18:58:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/s1773-2247(12)50061-4
Journal of Drug Delivery Science and Technology, v. 22, n. 4, p. 367-372, 2012.
1773-2247
http://hdl.handle.net/11449/219833
10.1016/s1773-2247(12)50061-4
2-s2.0-84865835486
url http://dx.doi.org/10.1016/s1773-2247(12)50061-4
http://hdl.handle.net/11449/219833
identifier_str_mv Journal of Drug Delivery Science and Technology, v. 22, n. 4, p. 367-372, 2012.
1773-2247
10.1016/s1773-2247(12)50061-4
2-s2.0-84865835486
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Drug Delivery Science and Technology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 367-372
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808129114399309824

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