Influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1806-83242009000300017 http://hdl.handle.net/11449/71496 |
Resumo: | Alcohol consumption is a risk indicator for periodontal disease. The purpose of this study was to morphometrically evaluate the influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats. Thirty-six female rats (Wistar, 120 days-old) were randomly divided into three groups that received a daily administration of a water diet (control, n = 12), a 10% alcohol diet (10% ethanol, n = 12) or a 20% alcohol diet (20% ethanol, n = 12). Four weeks after the onset of the experiment, cotton ligatures were placed around the cervix of the upper right second molar in six rats. The other 6 rats in each group remained unligated. The rats were sacrificed four weeks after ligature placement. The maxillary bones were removed and alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at 2 buccal and 2 palatal sites on the upper right second molar. Analyses between the ligated and unligated groups showed that the presence of ligature induced alveolar bone loss (p < 0.05). Unligated groups showed no significant differences between each other (p > 0.05). In the ligated groups, rats receiving 20% ethanol showed significantly greater bone loss compared to control rats or rats receiving 10% ethanol. These results demonstrate that alcohol consumption may increase alveolar bone loss in female rats in a dosedependent manner. |
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Influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in ratsAlcoholismAlveolar bone lossEthanolPeriodontitisRatsalveolar bone lossanimaldisease modeldrinking behaviorfemalejawligationpathologyperiodontal diseaseperiodontitisrandomizationratrisk factorWistar ratAlcohol DrinkingAlveolar Bone LossAlveolar ProcessAnimalsDisease Models, AnimalFemaleLigationPeriodontal Attachment LossRandom AllocationRats, WistarRisk FactorsAlcohol consumption is a risk indicator for periodontal disease. The purpose of this study was to morphometrically evaluate the influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats. Thirty-six female rats (Wistar, 120 days-old) were randomly divided into three groups that received a daily administration of a water diet (control, n = 12), a 10% alcohol diet (10% ethanol, n = 12) or a 20% alcohol diet (20% ethanol, n = 12). Four weeks after the onset of the experiment, cotton ligatures were placed around the cervix of the upper right second molar in six rats. The other 6 rats in each group remained unligated. The rats were sacrificed four weeks after ligature placement. The maxillary bones were removed and alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at 2 buccal and 2 palatal sites on the upper right second molar. Analyses between the ligated and unligated groups showed that the presence of ligature induced alveolar bone loss (p < 0.05). Unligated groups showed no significant differences between each other (p > 0.05). In the ligated groups, rats receiving 20% ethanol showed significantly greater bone loss compared to control rats or rats receiving 10% ethanol. These results demonstrate that alcohol consumption may increase alveolar bone loss in female rats in a dosedependent manner.Department of Dentistry University of Pindamonhangaba, Pindamonhangaba, SPDepartment of Periodontology School of Dentistry University of Taubaté, Taubaté, SPDepartment of Restorative Dentistry School of Dentistry Federal University of Santa Maria, Santa Maria, RSDepartment of Bioscience and Oral Diagnosis School of Dentistry of São José dos Campos São Paulo State University, São José dos Campos, SPDepartment of Bioscience and Oral Diagnosis School of Dentistry of São José dos Campos São Paulo State University, São José dos Campos, SPUniversity of PindamonhangabaUniversity of TaubatéFederal University of Santa MariaUniversidade Estadual Paulista (Unesp)de Souza, Daniela MartinsRicardo, Lucilene HernandesKantoski, Karla Zaninida Rocha, Rosilene Fernandes [UNESP]2014-05-27T11:24:35Z2014-05-27T11:24:35Z2009-12-28info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article326-332application/pdfhttp://dx.doi.org/10.1590/S1806-83242009000300017Brazilian Oral Research, v. 23, n. 3, p. 326-332, 2009.1806-83241807-3107http://hdl.handle.net/11449/7149610.1590/S1806-83242009000300017S1806-832420090003000172-s2.0-724491700122-s2.0-72449170012.pdf0190365234516027Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Oral Research1.223info:eu-repo/semantics/openAccess2024-01-06T06:22:35Zoai:repositorio.unesp.br:11449/71496Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T22:12:48.365248Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats |
title |
Influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats |
spellingShingle |
Influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats de Souza, Daniela Martins Alcoholism Alveolar bone loss Ethanol Periodontitis Rats alveolar bone loss animal disease model drinking behavior female jaw ligation pathology periodontal disease periodontitis randomization rat risk factor Wistar rat Alcohol Drinking Alveolar Bone Loss Alveolar Process Animals Disease Models, Animal Female Ligation Periodontal Attachment Loss Random Allocation Rats, Wistar Risk Factors |
title_short |
Influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats |
title_full |
Influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats |
title_fullStr |
Influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats |
title_full_unstemmed |
Influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats |
title_sort |
Influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats |
author |
de Souza, Daniela Martins |
author_facet |
de Souza, Daniela Martins Ricardo, Lucilene Hernandes Kantoski, Karla Zanini da Rocha, Rosilene Fernandes [UNESP] |
author_role |
author |
author2 |
Ricardo, Lucilene Hernandes Kantoski, Karla Zanini da Rocha, Rosilene Fernandes [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
University of Pindamonhangaba University of Taubaté Federal University of Santa Maria Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
de Souza, Daniela Martins Ricardo, Lucilene Hernandes Kantoski, Karla Zanini da Rocha, Rosilene Fernandes [UNESP] |
dc.subject.por.fl_str_mv |
Alcoholism Alveolar bone loss Ethanol Periodontitis Rats alveolar bone loss animal disease model drinking behavior female jaw ligation pathology periodontal disease periodontitis randomization rat risk factor Wistar rat Alcohol Drinking Alveolar Bone Loss Alveolar Process Animals Disease Models, Animal Female Ligation Periodontal Attachment Loss Random Allocation Rats, Wistar Risk Factors |
topic |
Alcoholism Alveolar bone loss Ethanol Periodontitis Rats alveolar bone loss animal disease model drinking behavior female jaw ligation pathology periodontal disease periodontitis randomization rat risk factor Wistar rat Alcohol Drinking Alveolar Bone Loss Alveolar Process Animals Disease Models, Animal Female Ligation Periodontal Attachment Loss Random Allocation Rats, Wistar Risk Factors |
description |
Alcohol consumption is a risk indicator for periodontal disease. The purpose of this study was to morphometrically evaluate the influence of alcohol consumption on alveolar bone level associated with ligature-induced periodontitis in rats. Thirty-six female rats (Wistar, 120 days-old) were randomly divided into three groups that received a daily administration of a water diet (control, n = 12), a 10% alcohol diet (10% ethanol, n = 12) or a 20% alcohol diet (20% ethanol, n = 12). Four weeks after the onset of the experiment, cotton ligatures were placed around the cervix of the upper right second molar in six rats. The other 6 rats in each group remained unligated. The rats were sacrificed four weeks after ligature placement. The maxillary bones were removed and alveolar bone loss was analyzed by measuring the distance between the cementoenamel junction and the alveolar bone crest at 2 buccal and 2 palatal sites on the upper right second molar. Analyses between the ligated and unligated groups showed that the presence of ligature induced alveolar bone loss (p < 0.05). Unligated groups showed no significant differences between each other (p > 0.05). In the ligated groups, rats receiving 20% ethanol showed significantly greater bone loss compared to control rats or rats receiving 10% ethanol. These results demonstrate that alcohol consumption may increase alveolar bone loss in female rats in a dosedependent manner. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-12-28 2014-05-27T11:24:35Z 2014-05-27T11:24:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1806-83242009000300017 Brazilian Oral Research, v. 23, n. 3, p. 326-332, 2009. 1806-8324 1807-3107 http://hdl.handle.net/11449/71496 10.1590/S1806-83242009000300017 S1806-83242009000300017 2-s2.0-72449170012 2-s2.0-72449170012.pdf 0190365234516027 |
url |
http://dx.doi.org/10.1590/S1806-83242009000300017 http://hdl.handle.net/11449/71496 |
identifier_str_mv |
Brazilian Oral Research, v. 23, n. 3, p. 326-332, 2009. 1806-8324 1807-3107 10.1590/S1806-83242009000300017 S1806-83242009000300017 2-s2.0-72449170012 2-s2.0-72449170012.pdf 0190365234516027 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Oral Research 1.223 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
326-332 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1808129405741957120 |