Animais de laboratório: O camundongo

• Autor(a) principal: Chorilli, Marlus [UNESP]
• Data de Publicação: 2007
• Outros Autores: Michelin, D. C. [UNESP], Salgado, Hérida Regina Nunes [UNESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/340; http://hdl.handle.net/11449/70144
• topic: Animal experimentation; General biology; Mouse; Techniques of risk in the experimentation; animal euthanasia; animal experiment; animal husbandry; blood sampling; cell culture; in vitro study; medical information; medical research; mouse; mouse strain; nonhuman; pain; reproduction

The animal experimentation in the scientific research has contributed excessively for the development of science and technology, promoting to long of the years the discovery of prophylactic measures and treatments for diseases that attack the humans. Animals of some species have been used in the last times, being the mouse the more intensely used and more deeply known scientifically. The objective of this work was to carry through a bibliographical survey including data of our research group, about the use of mice in the animal experimentation, approaching its general biology, reproduction physiology, creation systems, genetics, habitation, feeding, handling, pain and euthanasia, techniques of risk developed in the experimentation, blood collection, pharmacological and toxicological experiments. Although current trends praise the use of alternative methods (in vitro studies, cells cultures, etc.), the animal models, as the mouse, present as main advantage the supply of information on the organism as a whole, fact that is not obtained with other methods, what still it makes possible its utilization in scientific research.