Impact of the training program on lipid profile and cardiac health

Detalhes bibliográficos
Autor(a) principal: Burneiko, R. C.
Data de Publicação: 2004
Outros Autores: Diniz, Y. S., Faine, L. A., Galhardi, C. M., Padovani, C. R., Novelli, ELB, Cicogna, A. C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.4067/S0716-97602004000100006
http://hdl.handle.net/11449/36137
Resumo: The aim of this study was to investigate the effects of training programs on serum lipid profile and myocardial oxidative stress. Male Wistar rats (2 mo-old) were divided into three groups (n=8): sedentary (S), loadless trained (T) and trained-overload 2% body weight (TL). T and TL were trained through swimming for 9 weeks. T and TL rats had increased myocardial lipoperoxide (TBA) and lipid hydroperoxide (HP), whereas HP was higher in TL than in T animals. Superoxide dismutase (SOD) activities were lowest in TL. Myocardial glutathione peroxidase (GSH-Px) was lower in TL than in T and S rats. TL decreased HDL-cholesterol and increased LDL-cholesterol. The serum lactate dehydrogenase and TBA were increased, while SOD and GSH-Px activities were decreased in TL rats. Loadless training was able to improve HDL-cholesterol and to reduce LDL-cholesterol. In conclusion, the loadless training program induced beneficial effects on lipid profile, while overload training induced dyslipidemic profile that was associated with serum oxidative stress. The overload training program was deleterious relative to loadless training program, increasing myocardial oxidative stress.
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spelling Impact of the training program on lipid profile and cardiac healthtraininglipid profileoxidative stressheartserumThe aim of this study was to investigate the effects of training programs on serum lipid profile and myocardial oxidative stress. Male Wistar rats (2 mo-old) were divided into three groups (n=8): sedentary (S), loadless trained (T) and trained-overload 2% body weight (TL). T and TL were trained through swimming for 9 weeks. T and TL rats had increased myocardial lipoperoxide (TBA) and lipid hydroperoxide (HP), whereas HP was higher in TL than in T animals. Superoxide dismutase (SOD) activities were lowest in TL. Myocardial glutathione peroxidase (GSH-Px) was lower in TL than in T and S rats. TL decreased HDL-cholesterol and increased LDL-cholesterol. The serum lactate dehydrogenase and TBA were increased, while SOD and GSH-Px activities were decreased in TL rats. Loadless training was able to improve HDL-cholesterol and to reduce LDL-cholesterol. In conclusion, the loadless training program induced beneficial effects on lipid profile, while overload training induced dyslipidemic profile that was associated with serum oxidative stress. The overload training program was deleterious relative to loadless training program, increasing myocardial oxidative stress.Univ Estadual Paulista, Inst Biociencias, Dept Quim & Bioquim, BR-18618000 São Paulo, BrazilUNESP, Fac Med, São Paulo, BrazilUNESP, Inst Biol Sci, Dept Biostat, São Paulo, BrazilUniv Estadual Paulista, Inst Biociencias, Dept Quim & Bioquim, BR-18618000 São Paulo, BrazilUNESP, Fac Med, São Paulo, BrazilUNESP, Inst Biol Sci, Dept Biostat, São Paulo, BrazilSociedad Biolgia ChileUniversidade Estadual Paulista (Unesp)Burneiko, R. C.Diniz, Y. S.Faine, L. A.Galhardi, C. M.Padovani, C. R.Novelli, ELBCicogna, A. C.2014-05-20T15:25:47Z2014-05-20T15:25:47Z2004-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article53-59application/pdfhttp://dx.doi.org/10.4067/S0716-97602004000100006Biological Research. Santiago: Sociedad Biolgia Chile, v. 37, n. 1, p. 53-59, 2004.0716-9760http://hdl.handle.net/11449/3613710.4067/S0716-97602004000100006S0716-97602004000100006WOS:000221605400005WOS000221605400005.pdf8727897080522289Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBiological Research2.3570,654info:eu-repo/semantics/openAccess2023-12-03T06:14:16Zoai:repositorio.unesp.br:11449/36137Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T19:23:37.726817Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Impact of the training program on lipid profile and cardiac health
title Impact of the training program on lipid profile and cardiac health
spellingShingle Impact of the training program on lipid profile and cardiac health
Burneiko, R. C.
training
lipid profile
oxidative stress
heart
serum
title_short Impact of the training program on lipid profile and cardiac health
title_full Impact of the training program on lipid profile and cardiac health
title_fullStr Impact of the training program on lipid profile and cardiac health
title_full_unstemmed Impact of the training program on lipid profile and cardiac health
title_sort Impact of the training program on lipid profile and cardiac health
author Burneiko, R. C.
author_facet Burneiko, R. C.
Diniz, Y. S.
Faine, L. A.
Galhardi, C. M.
Padovani, C. R.
Novelli, ELB
Cicogna, A. C.
author_role author
author2 Diniz, Y. S.
Faine, L. A.
Galhardi, C. M.
Padovani, C. R.
Novelli, ELB
Cicogna, A. C.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Burneiko, R. C.
Diniz, Y. S.
Faine, L. A.
Galhardi, C. M.
Padovani, C. R.
Novelli, ELB
Cicogna, A. C.
dc.subject.por.fl_str_mv training
lipid profile
oxidative stress
heart
serum
topic training
lipid profile
oxidative stress
heart
serum
description The aim of this study was to investigate the effects of training programs on serum lipid profile and myocardial oxidative stress. Male Wistar rats (2 mo-old) were divided into three groups (n=8): sedentary (S), loadless trained (T) and trained-overload 2% body weight (TL). T and TL were trained through swimming for 9 weeks. T and TL rats had increased myocardial lipoperoxide (TBA) and lipid hydroperoxide (HP), whereas HP was higher in TL than in T animals. Superoxide dismutase (SOD) activities were lowest in TL. Myocardial glutathione peroxidase (GSH-Px) was lower in TL than in T and S rats. TL decreased HDL-cholesterol and increased LDL-cholesterol. The serum lactate dehydrogenase and TBA were increased, while SOD and GSH-Px activities were decreased in TL rats. Loadless training was able to improve HDL-cholesterol and to reduce LDL-cholesterol. In conclusion, the loadless training program induced beneficial effects on lipid profile, while overload training induced dyslipidemic profile that was associated with serum oxidative stress. The overload training program was deleterious relative to loadless training program, increasing myocardial oxidative stress.
publishDate 2004
dc.date.none.fl_str_mv 2004-01-01
2014-05-20T15:25:47Z
2014-05-20T15:25:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.4067/S0716-97602004000100006
Biological Research. Santiago: Sociedad Biolgia Chile, v. 37, n. 1, p. 53-59, 2004.
0716-9760
http://hdl.handle.net/11449/36137
10.4067/S0716-97602004000100006
S0716-97602004000100006
WOS:000221605400005
WOS000221605400005.pdf
8727897080522289
url http://dx.doi.org/10.4067/S0716-97602004000100006
http://hdl.handle.net/11449/36137
identifier_str_mv Biological Research. Santiago: Sociedad Biolgia Chile, v. 37, n. 1, p. 53-59, 2004.
0716-9760
10.4067/S0716-97602004000100006
S0716-97602004000100006
WOS:000221605400005
WOS000221605400005.pdf
8727897080522289
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Biological Research
2.357
0,654
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 53-59
application/pdf
dc.publisher.none.fl_str_mv Sociedad Biolgia Chile
publisher.none.fl_str_mv Sociedad Biolgia Chile
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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