Expresión de la ciclooxigenasa-2 en los carcinomas mamarios caninos primarios metastásicos y no metastásicos

Detalhes bibliográficos
Autor(a) principal: De Nardi, A. B. [UNESP]
Data de Publicação: 2013
Outros Autores: Daleck, C. R. [UNESP], Amorin, R. L. [UNESP], Huppes, R. R. [UNESP], Uscategui, R. A.R. [UNESP], Rodaski, S., Calderon, C., Neto, R. T. [UNESP]
Tipo de documento: Artigo
Idioma: spa
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.4067/S0301-732X2013000300012
http://hdl.handle.net/11449/227529
Resumo: The aim of this study was to detect the expression of ciclooxigenase-2 (COX-2) in metastatic primary carcinoma and non metastatic carcinoma, taking into consideration the relation between COX-2 and the progression of cancer. Evaluation of the COX-2 expression was achieved by immunohistochemistry analysis, using the primary polyclonal antibody anti-PGHS-2, clone PG 27, (Oxford Biomedical Research). The number of marked cells by the COX-2 antibody was higher (P > 0.001) in the metastatic primary carcinoma (81.25%) than non-metastatic (60.3%). There was a positive correlation between the number of labeled cells.
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spelling Expresión de la ciclooxigenasa-2 en los carcinomas mamarios caninos primarios metastásicos y no metastásicosCyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomasCancerCiclooxigenase-2DogsMammary neoplasmThe aim of this study was to detect the expression of ciclooxigenase-2 (COX-2) in metastatic primary carcinoma and non metastatic carcinoma, taking into consideration the relation between COX-2 and the progression of cancer. Evaluation of the COX-2 expression was achieved by immunohistochemistry analysis, using the primary polyclonal antibody anti-PGHS-2, clone PG 27, (Oxford Biomedical Research). The number of marked cells by the COX-2 antibody was higher (P > 0.001) in the metastatic primary carcinoma (81.25%) than non-metastatic (60.3%). There was a positive correlation between the number of labeled cells.Departamento de Clínica y Cirugía Veterinaria Universidad Estadual Paulista Campus de Jaboticabal, Paulo Donato Castellane, s/no, Jaboticabal, San PauloDepartamento de Clínica Veterinaria Universidad Estadual Paulista Campus de Botucatu, São PauloDoctorando del Programa de Clínica Veterinaria Universidad Estadual Paulista Campus Botucatu, São PauloDoctorando del Programa de Cirugía Veterinaria Universidad Estadual Paulista Campus Jaboticabal, São PauloDepartamento de Medicina Veterinaria Universidad Federal de Paraná Campus Curitiba, ParanáUniversidad Estadual del Norte de Paraná, Bandeirantes, ParanáDepartamento de Clínica y Cirugía Veterinaria Universidad Estadual Paulista Campus de Jaboticabal, Paulo Donato Castellane, s/no, Jaboticabal, San PauloDepartamento de Clínica Veterinaria Universidad Estadual Paulista Campus de Botucatu, São PauloDoctorando del Programa de Clínica Veterinaria Universidad Estadual Paulista Campus Botucatu, São PauloDoctorando del Programa de Cirugía Veterinaria Universidad Estadual Paulista Campus Jaboticabal, São PauloUniversidade Estadual Paulista (UNESP)Universidad Federal de ParanáUniversidad Estadual del Norte de ParanáDe Nardi, A. B. [UNESP]Daleck, C. R. [UNESP]Amorin, R. L. [UNESP]Huppes, R. R. [UNESP]Uscategui, R. A.R. [UNESP]Rodaski, S.Calderon, C.Neto, R. T. [UNESP]2022-04-29T07:13:47Z2022-04-29T07:13:47Z2013-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article311-316http://dx.doi.org/10.4067/S0301-732X2013000300012Archivos de Medicina Veterinaria, v. 45, n. 3, p. 311-316, 2013.0717-62010301-732Xhttp://hdl.handle.net/11449/22752910.4067/S0301-732X20130003000122-s2.0-84893272184Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPspaArchivos de Medicina Veterinariainfo:eu-repo/semantics/openAccess2024-09-05T18:45:19Zoai:repositorio.unesp.br:11449/227529Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-05T18:45:19Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Expresión de la ciclooxigenasa-2 en los carcinomas mamarios caninos primarios metastásicos y no metastásicos
Cyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomas
title Expresión de la ciclooxigenasa-2 en los carcinomas mamarios caninos primarios metastásicos y no metastásicos
spellingShingle Expresión de la ciclooxigenasa-2 en los carcinomas mamarios caninos primarios metastásicos y no metastásicos
De Nardi, A. B. [UNESP]
Cancer
Ciclooxigenase-2
Dogs
Mammary neoplasm
title_short Expresión de la ciclooxigenasa-2 en los carcinomas mamarios caninos primarios metastásicos y no metastásicos
title_full Expresión de la ciclooxigenasa-2 en los carcinomas mamarios caninos primarios metastásicos y no metastásicos
title_fullStr Expresión de la ciclooxigenasa-2 en los carcinomas mamarios caninos primarios metastásicos y no metastásicos
title_full_unstemmed Expresión de la ciclooxigenasa-2 en los carcinomas mamarios caninos primarios metastásicos y no metastásicos
title_sort Expresión de la ciclooxigenasa-2 en los carcinomas mamarios caninos primarios metastásicos y no metastásicos
author De Nardi, A. B. [UNESP]
author_facet De Nardi, A. B. [UNESP]
Daleck, C. R. [UNESP]
Amorin, R. L. [UNESP]
Huppes, R. R. [UNESP]
Uscategui, R. A.R. [UNESP]
Rodaski, S.
Calderon, C.
Neto, R. T. [UNESP]
author_role author
author2 Daleck, C. R. [UNESP]
Amorin, R. L. [UNESP]
Huppes, R. R. [UNESP]
Uscategui, R. A.R. [UNESP]
Rodaski, S.
Calderon, C.
Neto, R. T. [UNESP]
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
Universidad Federal de Paraná
Universidad Estadual del Norte de Paraná
dc.contributor.author.fl_str_mv De Nardi, A. B. [UNESP]
Daleck, C. R. [UNESP]
Amorin, R. L. [UNESP]
Huppes, R. R. [UNESP]
Uscategui, R. A.R. [UNESP]
Rodaski, S.
Calderon, C.
Neto, R. T. [UNESP]
dc.subject.por.fl_str_mv Cancer
Ciclooxigenase-2
Dogs
Mammary neoplasm
topic Cancer
Ciclooxigenase-2
Dogs
Mammary neoplasm
description The aim of this study was to detect the expression of ciclooxigenase-2 (COX-2) in metastatic primary carcinoma and non metastatic carcinoma, taking into consideration the relation between COX-2 and the progression of cancer. Evaluation of the COX-2 expression was achieved by immunohistochemistry analysis, using the primary polyclonal antibody anti-PGHS-2, clone PG 27, (Oxford Biomedical Research). The number of marked cells by the COX-2 antibody was higher (P > 0.001) in the metastatic primary carcinoma (81.25%) than non-metastatic (60.3%). There was a positive correlation between the number of labeled cells.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-01
2022-04-29T07:13:47Z
2022-04-29T07:13:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.4067/S0301-732X2013000300012
Archivos de Medicina Veterinaria, v. 45, n. 3, p. 311-316, 2013.
0717-6201
0301-732X
http://hdl.handle.net/11449/227529
10.4067/S0301-732X2013000300012
2-s2.0-84893272184
url http://dx.doi.org/10.4067/S0301-732X2013000300012
http://hdl.handle.net/11449/227529
identifier_str_mv Archivos de Medicina Veterinaria, v. 45, n. 3, p. 311-316, 2013.
0717-6201
0301-732X
10.4067/S0301-732X2013000300012
2-s2.0-84893272184
dc.language.iso.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv Archivos de Medicina Veterinaria
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 311-316
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
_version_ 1826304431019261952

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