Comparison between nerve conduction study and high-resolution ultrasonography with color doppler in type 1 and type 2 leprosy reactions
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.cnp.2021.02.003 http://hdl.handle.net/11449/218865 |
Resumo: | Objective: To analyze the role of high-resolution ultrasonography with color Doppler (HRUS with CD) to diagnose inflammatory activity (IA) in nerves of leprosy patients under type 1 (RT1) and 2 (RT2) reactions compared to Nerve Conduction Studies (NCS). Methods: Leprosy patients with signs or symptoms suggestive of neuritis (RT1 and RT2) without corticosteroids use were selected. They were evaluated by NCS and subsequently by HRUS with CD. Subacute segmental demyelination and the presence of blood flow, respectively, were considered signs of IA. The two methods were compared for their ability to diagnose patients with leprosy reactions. Results: A total of 257 nerves from 35 patients were evaluated. NCS and HRUS with CD diagnosed IA in 68% and 74% of patients, respectively. When both methods were used concomitantly, the diagnosis rate was 91.4%. HRUS with CD was particular helpful when there was minimal neurophysiological compromise in NCS or when motor potentials were not detected. Conclusion: HRUS with CD was able to detect leprosy reactions, especially when combined with NCS. It was especially useful in two opposite situations: nerves with only minor changes and those without motor response in NCS. Significance: Our data shows the usefulness of HRUS and CD, similar to NCS, as a tool to diagnose leprosy reactions. (C) 2021 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. |
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Repositório Institucional da UNESP |
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2946 |
spelling |
Comparison between nerve conduction study and high-resolution ultrasonography with color doppler in type 1 and type 2 leprosy reactionsLeprosy neuropathyNerve conduction studiesHigh-resolution ultrasonography and ColorDopplerLeprosy reactionsObjective: To analyze the role of high-resolution ultrasonography with color Doppler (HRUS with CD) to diagnose inflammatory activity (IA) in nerves of leprosy patients under type 1 (RT1) and 2 (RT2) reactions compared to Nerve Conduction Studies (NCS). Methods: Leprosy patients with signs or symptoms suggestive of neuritis (RT1 and RT2) without corticosteroids use were selected. They were evaluated by NCS and subsequently by HRUS with CD. Subacute segmental demyelination and the presence of blood flow, respectively, were considered signs of IA. The two methods were compared for their ability to diagnose patients with leprosy reactions. Results: A total of 257 nerves from 35 patients were evaluated. NCS and HRUS with CD diagnosed IA in 68% and 74% of patients, respectively. When both methods were used concomitantly, the diagnosis rate was 91.4%. HRUS with CD was particular helpful when there was minimal neurophysiological compromise in NCS or when motor potentials were not detected. Conclusion: HRUS with CD was able to detect leprosy reactions, especially when combined with NCS. It was especially useful in two opposite situations: nerves with only minor changes and those without motor response in NCS. Significance: Our data shows the usefulness of HRUS and CD, similar to NCS, as a tool to diagnose leprosy reactions. (C) 2021 International Federation of Clinical Neurophysiology. Published by Elsevier B.V.Lauro Souza Lima Inst, Neurophysiol Div, Bauru, SP, BrazilElsevier B.V.Lauro Souza Lima InstUniversidade Estadual Paulista (UNESP)Akita, J.Miller, L. H. G.Mello, F. M. C.Barreto, J. A.Moreira, A. L.Salgado, M. H.Kirchner, D. R.Garbino, J. A.2022-04-28T17:30:16Z2022-04-28T17:30:16Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article97-102http://dx.doi.org/10.1016/j.cnp.2021.02.003Clinical Neurophysiology Practice. Amsterdam: Elsevier, v. 6, p. 97-102, 2021.2467-981Xhttp://hdl.handle.net/11449/21886510.1016/j.cnp.2021.02.003WOS:000704863500015Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengClinical Neurophysiology Practiceinfo:eu-repo/semantics/openAccess2024-04-25T17:40:19Zoai:repositorio.unesp.br:11449/218865Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-04-25T17:40:19Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Comparison between nerve conduction study and high-resolution ultrasonography with color doppler in type 1 and type 2 leprosy reactions |
title |
Comparison between nerve conduction study and high-resolution ultrasonography with color doppler in type 1 and type 2 leprosy reactions |
spellingShingle |
Comparison between nerve conduction study and high-resolution ultrasonography with color doppler in type 1 and type 2 leprosy reactions Akita, J. Leprosy neuropathy Nerve conduction studies High-resolution ultrasonography and Color Doppler Leprosy reactions |
title_short |
Comparison between nerve conduction study and high-resolution ultrasonography with color doppler in type 1 and type 2 leprosy reactions |
title_full |
Comparison between nerve conduction study and high-resolution ultrasonography with color doppler in type 1 and type 2 leprosy reactions |
title_fullStr |
Comparison between nerve conduction study and high-resolution ultrasonography with color doppler in type 1 and type 2 leprosy reactions |
title_full_unstemmed |
Comparison between nerve conduction study and high-resolution ultrasonography with color doppler in type 1 and type 2 leprosy reactions |
title_sort |
Comparison between nerve conduction study and high-resolution ultrasonography with color doppler in type 1 and type 2 leprosy reactions |
author |
Akita, J. |
author_facet |
Akita, J. Miller, L. H. G. Mello, F. M. C. Barreto, J. A. Moreira, A. L. Salgado, M. H. Kirchner, D. R. Garbino, J. A. |
author_role |
author |
author2 |
Miller, L. H. G. Mello, F. M. C. Barreto, J. A. Moreira, A. L. Salgado, M. H. Kirchner, D. R. Garbino, J. A. |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Lauro Souza Lima Inst Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Akita, J. Miller, L. H. G. Mello, F. M. C. Barreto, J. A. Moreira, A. L. Salgado, M. H. Kirchner, D. R. Garbino, J. A. |
dc.subject.por.fl_str_mv |
Leprosy neuropathy Nerve conduction studies High-resolution ultrasonography and Color Doppler Leprosy reactions |
topic |
Leprosy neuropathy Nerve conduction studies High-resolution ultrasonography and Color Doppler Leprosy reactions |
description |
Objective: To analyze the role of high-resolution ultrasonography with color Doppler (HRUS with CD) to diagnose inflammatory activity (IA) in nerves of leprosy patients under type 1 (RT1) and 2 (RT2) reactions compared to Nerve Conduction Studies (NCS). Methods: Leprosy patients with signs or symptoms suggestive of neuritis (RT1 and RT2) without corticosteroids use were selected. They were evaluated by NCS and subsequently by HRUS with CD. Subacute segmental demyelination and the presence of blood flow, respectively, were considered signs of IA. The two methods were compared for their ability to diagnose patients with leprosy reactions. Results: A total of 257 nerves from 35 patients were evaluated. NCS and HRUS with CD diagnosed IA in 68% and 74% of patients, respectively. When both methods were used concomitantly, the diagnosis rate was 91.4%. HRUS with CD was particular helpful when there was minimal neurophysiological compromise in NCS or when motor potentials were not detected. Conclusion: HRUS with CD was able to detect leprosy reactions, especially when combined with NCS. It was especially useful in two opposite situations: nerves with only minor changes and those without motor response in NCS. Significance: Our data shows the usefulness of HRUS and CD, similar to NCS, as a tool to diagnose leprosy reactions. (C) 2021 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 2022-04-28T17:30:16Z 2022-04-28T17:30:16Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.cnp.2021.02.003 Clinical Neurophysiology Practice. Amsterdam: Elsevier, v. 6, p. 97-102, 2021. 2467-981X http://hdl.handle.net/11449/218865 10.1016/j.cnp.2021.02.003 WOS:000704863500015 |
url |
http://dx.doi.org/10.1016/j.cnp.2021.02.003 http://hdl.handle.net/11449/218865 |
identifier_str_mv |
Clinical Neurophysiology Practice. Amsterdam: Elsevier, v. 6, p. 97-102, 2021. 2467-981X 10.1016/j.cnp.2021.02.003 WOS:000704863500015 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Clinical Neurophysiology Practice |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
97-102 |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1803047119275163648 |