Análise da prescrição de medicamentos de pacientes hipertensos atendidos pelo SUS da rede municipal de saúde de Rincão - SP

• Autor(a) principal: Veronez, Leticia Lopes
• Data de Publicação: 2008
• Outros Autores: Simões, M. J S [UNESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/433; http://hdl.handle.net/11449/70613
• topic: Arterial hypertension; Drug interaction; Drug prescription; Pharmacoepidemiology; SUS; amlodipine; antihypertensive agent; atenolol; captopril; carbamazepine; cimetidine; digoxin; enalapril; furosemide; glibenclamide; hydrochlorothiazide; insulin; methyldopa; nifedipine; prednisone; propranolol; spironolactone; adult; aged; antihypertensive therapy; Brazil; data analysis; diabetes mellitus; drug use; female; health care; health center; human; hypertension; lifestyle; major clinical study; male; medical record; monotherapy; national health service; obesity; pharmacy; physician; prescription; smoking

The purpose of this study was to identify the drugs most often prescribed for hypertension at the Municipal Health Care Center of the town of Rincäo, State of São Paulo, Brazil, and the principal interactions arising from their association with other drugs, both anti-hypertensives and those in other classes. The study included 725 hypertensive patients registered at this health care center who were regularly seen by a physician every three months. Data were collected on age, sex, occurrence of diabetes, smoking, sedentary lifestyle and overweight, to obtain a profile of the hypertensive population of the area. Control records of all patients were available at the pharmacy in the health care center, where patients obtained their drugs once a month. Of the 725 patients, 38% were male and 62% female. Most (57%) were between 50 and 70 years of age, 21% used tobacco and 43% led a sedentary lifestyle. Single-drug therapy accounted for 33% of the prescriptions, multidrug therapy for 66%. In addition to anti-hypertensives, 50% of the patients took drugs of other therapeutic classes. Of those receiving multidrug therapy, 34% used three or more anti-hypertensives and 66% used only two of these drugs. Drug interactions were detected in as many as 47% of the prescriptions. Captopril was the drug that showed most interactions with others (54%), followed by hydrochlorothiazide (27%), furosemide (14%), propanolol (4%), and nifedipine (1%). The analysis revealed that drug consumption by the patients investigated is high, with a concomitantly high number of episodes of drug interaction.