Reductions in the Prevalence and Incidence of Geohelminth Infections following a City-wide Sanitation Program in a Brazilian Urban Centre

Detalhes bibliográficos
Autor(a) principal: Mascarini-Serra, Luciene Maura [UNESP]
Data de Publicação: 2010
Outros Autores: Telles, Carlos A., Prado, Matildes S., Mattos, Sheila Alvim, Strina, Agostino, Alcantara-Neves, Neuza M., Barreto, Mauricio L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1371/journal.pntd.0000588
http://hdl.handle.net/11449/42379
Resumo: Objective: In the city of Salvador, a large urban centre in Northeast Brazil, a city-wide sanitation intervention started in 1997, aimed at improving the sewerage coverage of households from 26% to 80%. Our aim was to study the impact of the intervention on the prevalence and incidence of geohelminths in the school-aged population.Methods: The study comprised two comparable cohorts: the first assembled in 1997, before the intervention, and the second assembled in 2003, after the intervention. Both were sampled from 24 sentinel areas chosen to represent the different environmental conditions throughout the city. Copro-parasitological examinations were carried out on every individual from both cohorts, at baseline and nine months later. Demographic, socio-economic, and environmental data were collected using semi-structured questionnaires and environmental surveys. A hierarchical modelling approach fitting a sequence of Poisson multivariate linear models was undertaken to test the effect of the intervention variables on the prevalence and incidence rate ratios.Findings: 729 and 890 children aged 7-14 years (mean = 10.4 y, SD = 0.05 y) were analysed over the first and the second cohorts, respectively. The adjusted reductions of the prevalence and incidence rates at the second in relation to the first cohort were 27% and 34%, 25% and 32%, 33% and 26%, and 82% and 42% for geohelminths overall, Ascaris lumbricoides, Trichuris trichiura, and hookworm, respectively. Hierarchical modelling showed that a major part of each of these reductions was explained by the intervention.Conclusion: Our results show that a city-wide sanitation program may reduce significantly the prevalence and incidence of geohelminths.
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spelling Reductions in the Prevalence and Incidence of Geohelminth Infections following a City-wide Sanitation Program in a Brazilian Urban CentreObjective: In the city of Salvador, a large urban centre in Northeast Brazil, a city-wide sanitation intervention started in 1997, aimed at improving the sewerage coverage of households from 26% to 80%. Our aim was to study the impact of the intervention on the prevalence and incidence of geohelminths in the school-aged population.Methods: The study comprised two comparable cohorts: the first assembled in 1997, before the intervention, and the second assembled in 2003, after the intervention. Both were sampled from 24 sentinel areas chosen to represent the different environmental conditions throughout the city. Copro-parasitological examinations were carried out on every individual from both cohorts, at baseline and nine months later. Demographic, socio-economic, and environmental data were collected using semi-structured questionnaires and environmental surveys. A hierarchical modelling approach fitting a sequence of Poisson multivariate linear models was undertaken to test the effect of the intervention variables on the prevalence and incidence rate ratios.Findings: 729 and 890 children aged 7-14 years (mean = 10.4 y, SD = 0.05 y) were analysed over the first and the second cohorts, respectively. The adjusted reductions of the prevalence and incidence rates at the second in relation to the first cohort were 27% and 34%, 25% and 32%, 33% and 26%, and 82% and 42% for geohelminths overall, Ascaris lumbricoides, Trichuris trichiura, and hookworm, respectively. Hierarchical modelling showed that a major part of each of these reductions was explained by the intervention.Conclusion: Our results show that a city-wide sanitation program may reduce significantly the prevalence and incidence of geohelminths.Programa de Apoio aos Núcleos de Excelência (PRONEX)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)post-doctoral junior fellowshipDepartment of Infrastructure, State Government of BahiaThe Wellcome Trust, UKEstadual Univ Julio Mesquita Filho UNESP, Dept Parasitol, Inst Biociencias, São Paulo, BrazilUniversidade Federal da Bahia (UFBA), Inst Saúde Colet, Salvador, BA, BrazilEstadual Univ Feira Santana, Dept Ciencias Exatas, Salvador, BrazilUniversidade Federal da Bahia (UFBA), Inst Ciencias Saude, Salvador, BA, BrazilEstadual Univ Julio Mesquita Filho UNESP, Dept Parasitol, Inst Biociencias, São Paulo, BrazilCNPq: 661086/1998-4post-doctoral junior fellowship: 152433/2007-4The Wellcome Trust, UK: 072405/Z/03/ZPublic Library ScienceUniversidade Estadual Paulista (Unesp)Universidade Federal da Bahia (UFBA)Universidade Estadual de Feira de Santana (UEFS)Mascarini-Serra, Luciene Maura [UNESP]Telles, Carlos A.Prado, Matildes S.Mattos, Sheila AlvimStrina, AgostinoAlcantara-Neves, Neuza M.Barreto, Mauricio L.2014-05-20T15:33:59Z2014-05-20T15:33:59Z2010-02-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7application/pdfhttp://dx.doi.org/10.1371/journal.pntd.0000588Plos Neglected Tropical Diseases. San Francisco: Public Library Science, v. 4, n. 2, p. 7, 2010.1935-2727http://hdl.handle.net/11449/4237910.1371/journal.pntd.0000588WOS:000275296200002WOS000275296200002.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPLoS Neglected Tropical Diseases2,589info:eu-repo/semantics/openAccess2023-11-04T06:09:46Zoai:repositorio.unesp.br:11449/42379Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T16:53:44.849304Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Reductions in the Prevalence and Incidence of Geohelminth Infections following a City-wide Sanitation Program in a Brazilian Urban Centre
title Reductions in the Prevalence and Incidence of Geohelminth Infections following a City-wide Sanitation Program in a Brazilian Urban Centre
spellingShingle Reductions in the Prevalence and Incidence of Geohelminth Infections following a City-wide Sanitation Program in a Brazilian Urban Centre
Mascarini-Serra, Luciene Maura [UNESP]
title_short Reductions in the Prevalence and Incidence of Geohelminth Infections following a City-wide Sanitation Program in a Brazilian Urban Centre
title_full Reductions in the Prevalence and Incidence of Geohelminth Infections following a City-wide Sanitation Program in a Brazilian Urban Centre
title_fullStr Reductions in the Prevalence and Incidence of Geohelminth Infections following a City-wide Sanitation Program in a Brazilian Urban Centre
title_full_unstemmed Reductions in the Prevalence and Incidence of Geohelminth Infections following a City-wide Sanitation Program in a Brazilian Urban Centre
title_sort Reductions in the Prevalence and Incidence of Geohelminth Infections following a City-wide Sanitation Program in a Brazilian Urban Centre
author Mascarini-Serra, Luciene Maura [UNESP]
author_facet Mascarini-Serra, Luciene Maura [UNESP]
Telles, Carlos A.
Prado, Matildes S.
Mattos, Sheila Alvim
Strina, Agostino
Alcantara-Neves, Neuza M.
Barreto, Mauricio L.
author_role author
author2 Telles, Carlos A.
Prado, Matildes S.
Mattos, Sheila Alvim
Strina, Agostino
Alcantara-Neves, Neuza M.
Barreto, Mauricio L.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade Federal da Bahia (UFBA)
Universidade Estadual de Feira de Santana (UEFS)
dc.contributor.author.fl_str_mv Mascarini-Serra, Luciene Maura [UNESP]
Telles, Carlos A.
Prado, Matildes S.
Mattos, Sheila Alvim
Strina, Agostino
Alcantara-Neves, Neuza M.
Barreto, Mauricio L.
description Objective: In the city of Salvador, a large urban centre in Northeast Brazil, a city-wide sanitation intervention started in 1997, aimed at improving the sewerage coverage of households from 26% to 80%. Our aim was to study the impact of the intervention on the prevalence and incidence of geohelminths in the school-aged population.Methods: The study comprised two comparable cohorts: the first assembled in 1997, before the intervention, and the second assembled in 2003, after the intervention. Both were sampled from 24 sentinel areas chosen to represent the different environmental conditions throughout the city. Copro-parasitological examinations were carried out on every individual from both cohorts, at baseline and nine months later. Demographic, socio-economic, and environmental data were collected using semi-structured questionnaires and environmental surveys. A hierarchical modelling approach fitting a sequence of Poisson multivariate linear models was undertaken to test the effect of the intervention variables on the prevalence and incidence rate ratios.Findings: 729 and 890 children aged 7-14 years (mean = 10.4 y, SD = 0.05 y) were analysed over the first and the second cohorts, respectively. The adjusted reductions of the prevalence and incidence rates at the second in relation to the first cohort were 27% and 34%, 25% and 32%, 33% and 26%, and 82% and 42% for geohelminths overall, Ascaris lumbricoides, Trichuris trichiura, and hookworm, respectively. Hierarchical modelling showed that a major part of each of these reductions was explained by the intervention.Conclusion: Our results show that a city-wide sanitation program may reduce significantly the prevalence and incidence of geohelminths.
publishDate 2010
dc.date.none.fl_str_mv 2010-02-01
2014-05-20T15:33:59Z
2014-05-20T15:33:59Z
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format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1371/journal.pntd.0000588
Plos Neglected Tropical Diseases. San Francisco: Public Library Science, v. 4, n. 2, p. 7, 2010.
1935-2727
http://hdl.handle.net/11449/42379
10.1371/journal.pntd.0000588
WOS:000275296200002
WOS000275296200002.pdf
url http://dx.doi.org/10.1371/journal.pntd.0000588
http://hdl.handle.net/11449/42379
identifier_str_mv Plos Neglected Tropical Diseases. San Francisco: Public Library Science, v. 4, n. 2, p. 7, 2010.
1935-2727
10.1371/journal.pntd.0000588
WOS:000275296200002
WOS000275296200002.pdf
dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv PLoS Neglected Tropical Diseases
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dc.publisher.none.fl_str_mv Public Library Science
publisher.none.fl_str_mv Public Library Science
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
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instname_str Universidade Estadual Paulista (UNESP)
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