High-performance liquid chromatography determination of praziquantel in tablets and raw materials

Detalhes bibliográficos
Autor(a) principal: Mainardes, Rubiana M. [UNESP]
Data de Publicação: 2006
Outros Autores: Cinto, Priscila O. [UNESP], Gremião, Maria P.D. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://www.latamjpharm.org/trabajos/25/4/LAJOP_25_4_2_3_PYE8T8NG83.pdf
http://hdl.handle.net/11449/69152
Resumo: A specific and sensitive high-performance liquid chromatographic method was developed for the assay of praziquantel in raw materials and tablets. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay in the wavelenght selected. The method validation yielded good results and included the range, linearity, precision, accuracy, specificity and recovery.
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spelling High-performance liquid chromatography determination of praziquantel in tablets and raw materialsHPLCPraziquantelQuality controlpraziquantelaccuracydrug formulationdrug structurehigh performance liquid chromatographytablet formulationvalidation processA specific and sensitive high-performance liquid chromatographic method was developed for the assay of praziquantel in raw materials and tablets. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay in the wavelenght selected. The method validation yielded good results and included the range, linearity, precision, accuracy, specificity and recovery.Departamento de Fármacos e Medicamentos Programa de Pós-graduação em Ciências Farmacêuticas Faculdade de Ciências Farmacêuticas - UNESP, Rod. Araraquara-Jaú, Km 1, Araraquara, Cep 14802-902, SPDepartamento de Fármacos e Medicamentos Programa de Pós-graduação em Ciências Farmacêuticas Faculdade de Ciências Farmacêuticas - UNESP, Rod. Araraquara-Jaú, Km 1, Araraquara, Cep 14802-902, SPUniversidade Estadual Paulista (Unesp)Mainardes, Rubiana M. [UNESP]Cinto, Priscila O. [UNESP]Gremião, Maria P.D. [UNESP]2014-05-27T11:22:00Z2014-05-27T11:22:00Z2006-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article567-570http://www.latamjpharm.org/trabajos/25/4/LAJOP_25_4_2_3_PYE8T8NG83.pdfActa Farmaceutica Bonaerense, v. 25, n. 4, p. 567-570, 2006.0326-2383http://hdl.handle.net/11449/691522-s2.0-33947651597Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengActa Farmaceutica Bonaerense0.4010,152info:eu-repo/semantics/openAccess2024-06-24T13:44:50Zoai:repositorio.unesp.br:11449/69152Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T13:41:22.037049Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv High-performance liquid chromatography determination of praziquantel in tablets and raw materials
title High-performance liquid chromatography determination of praziquantel in tablets and raw materials
spellingShingle High-performance liquid chromatography determination of praziquantel in tablets and raw materials
Mainardes, Rubiana M. [UNESP]
HPLC
Praziquantel
Quality control
praziquantel
accuracy
drug formulation
drug structure
high performance liquid chromatography
tablet formulation
validation process
title_short High-performance liquid chromatography determination of praziquantel in tablets and raw materials
title_full High-performance liquid chromatography determination of praziquantel in tablets and raw materials
title_fullStr High-performance liquid chromatography determination of praziquantel in tablets and raw materials
title_full_unstemmed High-performance liquid chromatography determination of praziquantel in tablets and raw materials
title_sort High-performance liquid chromatography determination of praziquantel in tablets and raw materials
author Mainardes, Rubiana M. [UNESP]
author_facet Mainardes, Rubiana M. [UNESP]
Cinto, Priscila O. [UNESP]
Gremião, Maria P.D. [UNESP]
author_role author
author2 Cinto, Priscila O. [UNESP]
Gremião, Maria P.D. [UNESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Mainardes, Rubiana M. [UNESP]
Cinto, Priscila O. [UNESP]
Gremião, Maria P.D. [UNESP]
dc.subject.por.fl_str_mv HPLC
Praziquantel
Quality control
praziquantel
accuracy
drug formulation
drug structure
high performance liquid chromatography
tablet formulation
validation process
topic HPLC
Praziquantel
Quality control
praziquantel
accuracy
drug formulation
drug structure
high performance liquid chromatography
tablet formulation
validation process
description A specific and sensitive high-performance liquid chromatographic method was developed for the assay of praziquantel in raw materials and tablets. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay in the wavelenght selected. The method validation yielded good results and included the range, linearity, precision, accuracy, specificity and recovery.
publishDate 2006
dc.date.none.fl_str_mv 2006-10-01
2014-05-27T11:22:00Z
2014-05-27T11:22:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.latamjpharm.org/trabajos/25/4/LAJOP_25_4_2_3_PYE8T8NG83.pdf
Acta Farmaceutica Bonaerense, v. 25, n. 4, p. 567-570, 2006.
0326-2383
http://hdl.handle.net/11449/69152
2-s2.0-33947651597
url http://www.latamjpharm.org/trabajos/25/4/LAJOP_25_4_2_3_PYE8T8NG83.pdf
http://hdl.handle.net/11449/69152
identifier_str_mv Acta Farmaceutica Bonaerense, v. 25, n. 4, p. 567-570, 2006.
0326-2383
2-s2.0-33947651597
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Acta Farmaceutica Bonaerense
0.401
0,152
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 567-570
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1808128265038069760

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